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Transcranial magnetic stimulation as a feasible, non-invasive, neuromodulatory intervention in fetal alcohol spectrum disorders. A very first proof of concept
CONCLUSION: FASD is a very complex disorder that is difficult to treat. In addition, comorbidities as atypical responses to pharmacotherapies are frequent. For this reason, non-invasive, innovative therapies for children with FASD have to be developed. For the first time, rTMS was shown to be safe, tolerable, and acceptable and thus well feasible in paediatric patients with FASD. Further clinical studies with larger samples are needed to identify effective stimulation protocols and to evaluate treatment response.PMID:37913649 | DOI:10.1016/j.ejpn.2023.10.004 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - November 1, 2023 Category: Neurology Authors: Anja Melder Esther Wittmann Lucia Bulubas Beate Dornheim Katharina Kerber Ulrike Vogelmann Mattia Campana Jasmin Hubert Vivien Schmidt Florian Heinen Frank Padberg Mirjam N Landgraf Source Type: research

Transcranial magnetic stimulation as a feasible, non-invasive, neuromodulatory intervention in fetal alcohol spectrum disorders. A very first proof of concept
CONCLUSION: FASD is a very complex disorder that is difficult to treat. In addition, comorbidities as atypical responses to pharmacotherapies are frequent. For this reason, non-invasive, innovative therapies for children with FASD have to be developed. For the first time, rTMS was shown to be safe, tolerable, and acceptable and thus well feasible in paediatric patients with FASD. Further clinical studies with larger samples are needed to identify effective stimulation protocols and to evaluate treatment response.PMID:37913649 | DOI:10.1016/j.ejpn.2023.10.004 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - November 1, 2023 Category: Neurology Authors: Anja Melder Esther Wittmann Lucia Bulubas Beate Dornheim Katharina Kerber Ulrike Vogelmann Mattia Campana Jasmin Hubert Vivien Schmidt Florian Heinen Frank Padberg Mirjam N Landgraf Source Type: research

Transcranial magnetic stimulation as a feasible, non-invasive, neuromodulatory intervention in fetal alcohol spectrum disorders. A very first proof of concept
CONCLUSION: FASD is a very complex disorder that is difficult to treat. In addition, comorbidities as atypical responses to pharmacotherapies are frequent. For this reason, non-invasive, innovative therapies for children with FASD have to be developed. For the first time, rTMS was shown to be safe, tolerable, and acceptable and thus well feasible in paediatric patients with FASD. Further clinical studies with larger samples are needed to identify effective stimulation protocols and to evaluate treatment response.PMID:37913649 | DOI:10.1016/j.ejpn.2023.10.004 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - November 1, 2023 Category: Neurology Authors: Anja Melder Esther Wittmann Lucia Bulubas Beate Dornheim Katharina Kerber Ulrike Vogelmann Mattia Campana Jasmin Hubert Vivien Schmidt Florian Heinen Frank Padberg Mirjam N Landgraf Source Type: research

Transcranial magnetic stimulation as a feasible, non-invasive, neuromodulatory intervention in fetal alcohol spectrum disorders. A very first proof of concept
CONCLUSION: FASD is a very complex disorder that is difficult to treat. In addition, comorbidities as atypical responses to pharmacotherapies are frequent. For this reason, non-invasive, innovative therapies for children with FASD have to be developed. For the first time, rTMS was shown to be safe, tolerable, and acceptable and thus well feasible in paediatric patients with FASD. Further clinical studies with larger samples are needed to identify effective stimulation protocols and to evaluate treatment response.PMID:37913649 | DOI:10.1016/j.ejpn.2023.10.004 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - November 1, 2023 Category: Neurology Authors: Anja Melder Esther Wittmann Lucia Bulubas Beate Dornheim Katharina Kerber Ulrike Vogelmann Mattia Campana Jasmin Hubert Vivien Schmidt Florian Heinen Frank Padberg Mirjam N Landgraf Source Type: research

Transcranial magnetic stimulation as a feasible, non-invasive, neuromodulatory intervention in fetal alcohol spectrum disorders. A very first proof of concept
CONCLUSION: FASD is a very complex disorder that is difficult to treat. In addition, comorbidities as atypical responses to pharmacotherapies are frequent. For this reason, non-invasive, innovative therapies for children with FASD have to be developed. For the first time, rTMS was shown to be safe, tolerable, and acceptable and thus well feasible in paediatric patients with FASD. Further clinical studies with larger samples are needed to identify effective stimulation protocols and to evaluate treatment response.PMID:37913649 | DOI:10.1016/j.ejpn.2023.10.004 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - November 1, 2023 Category: Neurology Authors: Anja Melder Esther Wittmann Lucia Bulubas Beate Dornheim Katharina Kerber Ulrike Vogelmann Mattia Campana Jasmin Hubert Vivien Schmidt Florian Heinen Frank Padberg Mirjam N Landgraf Source Type: research

Transcranial magnetic stimulation as a feasible, non-invasive, neuromodulatory intervention in fetal alcohol spectrum disorders. A very first proof of concept
CONCLUSION: FASD is a very complex disorder that is difficult to treat. In addition, comorbidities as atypical responses to pharmacotherapies are frequent. For this reason, non-invasive, innovative therapies for children with FASD have to be developed. For the first time, rTMS was shown to be safe, tolerable, and acceptable and thus well feasible in paediatric patients with FASD. Further clinical studies with larger samples are needed to identify effective stimulation protocols and to evaluate treatment response.PMID:37913649 | DOI:10.1016/j.ejpn.2023.10.004 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - November 1, 2023 Category: Neurology Authors: Anja Melder Esther Wittmann Lucia Bulubas Beate Dornheim Katharina Kerber Ulrike Vogelmann Mattia Campana Jasmin Hubert Vivien Schmidt Florian Heinen Frank Padberg Mirjam N Landgraf Source Type: research

Transcranial magnetic stimulation as a feasible, non-invasive, neuromodulatory intervention in fetal alcohol spectrum disorders. A very first proof of concept
CONCLUSION: FASD is a very complex disorder that is difficult to treat. In addition, comorbidities as atypical responses to pharmacotherapies are frequent. For this reason, non-invasive, innovative therapies for children with FASD have to be developed. For the first time, rTMS was shown to be safe, tolerable, and acceptable and thus well feasible in paediatric patients with FASD. Further clinical studies with larger samples are needed to identify effective stimulation protocols and to evaluate treatment response.PMID:37913649 | DOI:10.1016/j.ejpn.2023.10.004 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - November 1, 2023 Category: Neurology Authors: Anja Melder Esther Wittmann Lucia Bulubas Beate Dornheim Katharina Kerber Ulrike Vogelmann Mattia Campana Jasmin Hubert Vivien Schmidt Florian Heinen Frank Padberg Mirjam N Landgraf Source Type: research

Transcranial magnetic stimulation as a feasible, non-invasive, neuromodulatory intervention in fetal alcohol spectrum disorders. A very first proof of concept
CONCLUSION: FASD is a very complex disorder that is difficult to treat. In addition, comorbidities as atypical responses to pharmacotherapies are frequent. For this reason, non-invasive, innovative therapies for children with FASD have to be developed. For the first time, rTMS was shown to be safe, tolerable, and acceptable and thus well feasible in paediatric patients with FASD. Further clinical studies with larger samples are needed to identify effective stimulation protocols and to evaluate treatment response.PMID:37913649 | DOI:10.1016/j.ejpn.2023.10.004 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - November 1, 2023 Category: Neurology Authors: Anja Melder Esther Wittmann Lucia Bulubas Beate Dornheim Katharina Kerber Ulrike Vogelmann Mattia Campana Jasmin Hubert Vivien Schmidt Florian Heinen Frank Padberg Mirjam N Landgraf Source Type: research

Transcranial magnetic stimulation as a feasible, non-invasive, neuromodulatory intervention in fetal alcohol spectrum disorders. A very first proof of concept
CONCLUSION: FASD is a very complex disorder that is difficult to treat. In addition, comorbidities as atypical responses to pharmacotherapies are frequent. For this reason, non-invasive, innovative therapies for children with FASD have to be developed. For the first time, rTMS was shown to be safe, tolerable, and acceptable and thus well feasible in paediatric patients with FASD. Further clinical studies with larger samples are needed to identify effective stimulation protocols and to evaluate treatment response.PMID:37913649 | DOI:10.1016/j.ejpn.2023.10.004 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - November 1, 2023 Category: Neurology Authors: Anja Melder Esther Wittmann Lucia Bulubas Beate Dornheim Katharina Kerber Ulrike Vogelmann Mattia Campana Jasmin Hubert Vivien Schmidt Florian Heinen Frank Padberg Mirjam N Landgraf Source Type: research

Transcranial magnetic stimulation as a feasible, non-invasive, neuromodulatory intervention in fetal alcohol spectrum disorders. A very first proof of concept
CONCLUSION: FASD is a very complex disorder that is difficult to treat. In addition, comorbidities as atypical responses to pharmacotherapies are frequent. For this reason, non-invasive, innovative therapies for children with FASD have to be developed. For the first time, rTMS was shown to be safe, tolerable, and acceptable and thus well feasible in paediatric patients with FASD. Further clinical studies with larger samples are needed to identify effective stimulation protocols and to evaluate treatment response.PMID:37913649 | DOI:10.1016/j.ejpn.2023.10.004 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - November 1, 2023 Category: Neurology Authors: Anja Melder Esther Wittmann Lucia Bulubas Beate Dornheim Katharina Kerber Ulrike Vogelmann Mattia Campana Jasmin Hubert Vivien Schmidt Florian Heinen Frank Padberg Mirjam N Landgraf Source Type: research

Transcranial magnetic stimulation as a feasible, non-invasive, neuromodulatory intervention in fetal alcohol spectrum disorders. A very first proof of concept
CONCLUSION: FASD is a very complex disorder that is difficult to treat. In addition, comorbidities as atypical responses to pharmacotherapies are frequent. For this reason, non-invasive, innovative therapies for children with FASD have to be developed. For the first time, rTMS was shown to be safe, tolerable, and acceptable and thus well feasible in paediatric patients with FASD. Further clinical studies with larger samples are needed to identify effective stimulation protocols and to evaluate treatment response.PMID:37913649 | DOI:10.1016/j.ejpn.2023.10.004 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - November 1, 2023 Category: Neurology Authors: Anja Melder Esther Wittmann Lucia Bulubas Beate Dornheim Katharina Kerber Ulrike Vogelmann Mattia Campana Jasmin Hubert Vivien Schmidt Florian Heinen Frank Padberg Mirjam N Landgraf Source Type: research

Long-term motor development after hypothermia-treated hypoxic-ischaemic encephalopathy
CONCLUSION: Among survivors of hypothermia-treated HIE free of moderate/severe cerebral palsy, a third had MABC-2 scores indicating risk of motor difficulties at 11.1 years of age. As motor difficulties became more apparent over time, we suggest that children treated with TH due to neonatal HIE should be followed into at least middle school age.PMID:37862884 | DOI:10.1016/j.ejpn.2023.10.003 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - October 20, 2023 Category: Neurology Authors: Mimmi Eriksson Westblad Kristina L öwing Katarina Robertsson Grossmann Mats Blennow Katarina Lindstr öm Source Type: research

Long-term motor development after hypothermia-treated hypoxic-ischaemic encephalopathy
CONCLUSION: Among survivors of hypothermia-treated HIE free of moderate/severe cerebral palsy, a third had MABC-2 scores indicating risk of motor difficulties at 11.1 years of age. As motor difficulties became more apparent over time, we suggest that children treated with TH due to neonatal HIE should be followed into at least middle school age.PMID:37862884 | DOI:10.1016/j.ejpn.2023.10.003 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - October 20, 2023 Category: Neurology Authors: Mimmi Eriksson Westblad Kristina L öwing Katarina Robertsson Grossmann Mats Blennow Katarina Lindstr öm Source Type: research

Long-term motor development after hypothermia-treated hypoxic-ischaemic encephalopathy
CONCLUSION: Among survivors of hypothermia-treated HIE free of moderate/severe cerebral palsy, a third had MABC-2 scores indicating risk of motor difficulties at 11.1 years of age. As motor difficulties became more apparent over time, we suggest that children treated with TH due to neonatal HIE should be followed into at least middle school age.PMID:37862884 | DOI:10.1016/j.ejpn.2023.10.003 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - October 20, 2023 Category: Neurology Authors: Mimmi Eriksson Westblad Kristina L öwing Katarina Robertsson Grossmann Mats Blennow Katarina Lindstr öm Source Type: research

Long-term motor development after hypothermia-treated hypoxic-ischaemic encephalopathy
CONCLUSION: Among survivors of hypothermia-treated HIE free of moderate/severe cerebral palsy, a third had MABC-2 scores indicating risk of motor difficulties at 11.1 years of age. As motor difficulties became more apparent over time, we suggest that children treated with TH due to neonatal HIE should be followed into at least middle school age.PMID:37862884 | DOI:10.1016/j.ejpn.2023.10.003 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - October 20, 2023 Category: Neurology Authors: Mimmi Eriksson Westblad Kristina L öwing Katarina Robertsson Grossmann Mats Blennow Katarina Lindstr öm Source Type: research