Transcranial magnetic stimulation as a feasible, non-invasive, neuromodulatory intervention in fetal alcohol spectrum disorders. A very first proof of concept
CONCLUSION: FASD is a very complex disorder that is difficult to treat. In addition, comorbidities as atypical responses to pharmacotherapies are frequent. For this reason, non-invasive, innovative therapies for children with FASD have to be developed. For the first time, rTMS was shown to be safe, tolerable, and acceptable and thus well feasible in paediatric patients with FASD. Further clinical studies with larger samples are needed to identify effective stimulation protocols and to evaluate treatment response.PMID:37913649 | DOI:10.1016/j.ejpn.2023.10.004 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - November 1, 2023 Category: Neurology Authors: Anja Melder Esther Wittmann Lucia Bulubas Beate Dornheim Katharina Kerber Ulrike Vogelmann Mattia Campana Jasmin Hubert Vivien Schmidt Florian Heinen Frank Padberg Mirjam N Landgraf Source Type: research

Long-term motor development after hypothermia-treated hypoxic-ischaemic encephalopathy
CONCLUSION: Among survivors of hypothermia-treated HIE free of moderate/severe cerebral palsy, a third had MABC-2 scores indicating risk of motor difficulties at 11.1 years of age. As motor difficulties became more apparent over time, we suggest that children treated with TH due to neonatal HIE should be followed into at least middle school age.PMID:37862884 | DOI:10.1016/j.ejpn.2023.10.003 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - October 20, 2023 Category: Neurology Authors: Mimmi Eriksson Westblad Kristina L öwing Katarina Robertsson Grossmann Mats Blennow Katarina Lindstr öm Source Type: research

Long-term motor development after hypothermia-treated hypoxic-ischaemic encephalopathy
CONCLUSION: Among survivors of hypothermia-treated HIE free of moderate/severe cerebral palsy, a third had MABC-2 scores indicating risk of motor difficulties at 11.1 years of age. As motor difficulties became more apparent over time, we suggest that children treated with TH due to neonatal HIE should be followed into at least middle school age.PMID:37862884 | DOI:10.1016/j.ejpn.2023.10.003 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - October 20, 2023 Category: Neurology Authors: Mimmi Eriksson Westblad Kristina L öwing Katarina Robertsson Grossmann Mats Blennow Katarina Lindstr öm Source Type: research

Long-term motor development after hypothermia-treated hypoxic-ischaemic encephalopathy
CONCLUSION: Among survivors of hypothermia-treated HIE free of moderate/severe cerebral palsy, a third had MABC-2 scores indicating risk of motor difficulties at 11.1 years of age. As motor difficulties became more apparent over time, we suggest that children treated with TH due to neonatal HIE should be followed into at least middle school age.PMID:37862884 | DOI:10.1016/j.ejpn.2023.10.003 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - October 20, 2023 Category: Neurology Authors: Mimmi Eriksson Westblad Kristina L öwing Katarina Robertsson Grossmann Mats Blennow Katarina Lindstr öm Source Type: research

Long-term motor development after hypothermia-treated hypoxic-ischaemic encephalopathy
CONCLUSION: Among survivors of hypothermia-treated HIE free of moderate/severe cerebral palsy, a third had MABC-2 scores indicating risk of motor difficulties at 11.1 years of age. As motor difficulties became more apparent over time, we suggest that children treated with TH due to neonatal HIE should be followed into at least middle school age.PMID:37862884 | DOI:10.1016/j.ejpn.2023.10.003 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - October 20, 2023 Category: Neurology Authors: Mimmi Eriksson Westblad Kristina L öwing Katarina Robertsson Grossmann Mats Blennow Katarina Lindstr öm Source Type: research

Long-term motor development after hypothermia-treated hypoxic-ischaemic encephalopathy
CONCLUSION: Among survivors of hypothermia-treated HIE free of moderate/severe cerebral palsy, a third had MABC-2 scores indicating risk of motor difficulties at 11.1 years of age. As motor difficulties became more apparent over time, we suggest that children treated with TH due to neonatal HIE should be followed into at least middle school age.PMID:37862884 | DOI:10.1016/j.ejpn.2023.10.003 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - October 20, 2023 Category: Neurology Authors: Mimmi Eriksson Westblad Kristina L öwing Katarina Robertsson Grossmann Mats Blennow Katarina Lindstr öm Source Type: research

Long-term motor development after hypothermia-treated hypoxic-ischaemic encephalopathy
CONCLUSION: Among survivors of hypothermia-treated HIE free of moderate/severe cerebral palsy, a third had MABC-2 scores indicating risk of motor difficulties at 11.1 years of age. As motor difficulties became more apparent over time, we suggest that children treated with TH due to neonatal HIE should be followed into at least middle school age.PMID:37862884 | DOI:10.1016/j.ejpn.2023.10.003 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - October 20, 2023 Category: Neurology Authors: Mimmi Eriksson Westblad Kristina L öwing Katarina Robertsson Grossmann Mats Blennow Katarina Lindstr öm Source Type: research

Long-term motor development after hypothermia-treated hypoxic-ischaemic encephalopathy
CONCLUSION: Among survivors of hypothermia-treated HIE free of moderate/severe cerebral palsy, a third had MABC-2 scores indicating risk of motor difficulties at 11.1 years of age. As motor difficulties became more apparent over time, we suggest that children treated with TH due to neonatal HIE should be followed into at least middle school age.PMID:37862884 | DOI:10.1016/j.ejpn.2023.10.003 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - October 20, 2023 Category: Neurology Authors: Mimmi Eriksson Westblad Kristina L öwing Katarina Robertsson Grossmann Mats Blennow Katarina Lindstr öm Source Type: research

Long-term motor development after hypothermia-treated hypoxic-ischaemic encephalopathy
CONCLUSION: Among survivors of hypothermia-treated HIE free of moderate/severe cerebral palsy, a third had MABC-2 scores indicating risk of motor difficulties at 11.1 years of age. As motor difficulties became more apparent over time, we suggest that children treated with TH due to neonatal HIE should be followed into at least middle school age.PMID:37862884 | DOI:10.1016/j.ejpn.2023.10.003 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - October 20, 2023 Category: Neurology Authors: Mimmi Eriksson Westblad Kristina L öwing Katarina Robertsson Grossmann Mats Blennow Katarina Lindstr öm Source Type: research

Long-term motor development after hypothermia-treated hypoxic-ischaemic encephalopathy
CONCLUSION: Among survivors of hypothermia-treated HIE free of moderate/severe cerebral palsy, a third had MABC-2 scores indicating risk of motor difficulties at 11.1 years of age. As motor difficulties became more apparent over time, we suggest that children treated with TH due to neonatal HIE should be followed into at least middle school age.PMID:37862884 | DOI:10.1016/j.ejpn.2023.10.003 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - October 20, 2023 Category: Neurology Authors: Mimmi Eriksson Westblad Kristina L öwing Katarina Robertsson Grossmann Mats Blennow Katarina Lindstr öm Source Type: research

Trajectories of motor function in children with Duchenne muscular dystrophy: A longitudinal study on a Colombian population
Eur J Paediatr Neurol. 2023 Oct 14;47:105-109. doi: 10.1016/j.ejpn.2023.10.002. Online ahead of print.ABSTRACTDuchenne Muscular Dystrophy (DMD) is characterized by an initial increase in motor function followed by a plateau phase and then entering a phase of steady decline. However, motor evolution of DMD have not been evaluated in developing countries. Therefore, this study aims to evaluate the trajectory of motor function in a sample of Colombian children with DMD. We included 119 children with DMD aged 4.8-19.3 years (mean follow-up = 1.7 years). A linear mixed model was used with age as the time scale and adjusted for ...
Source: European Journal of Paediatric Neurology - October 19, 2023 Category: Neurology Authors: Fernando Ortiz-Corredor Andres Sandoval-Salcedo Sandra Castellar-Leones Diana Soto-Pena Edicson Ru íz-Ospina Fernando Suarez-Obando Source Type: research

Trajectories of motor function in children with Duchenne muscular dystrophy: A longitudinal study on a Colombian population
Eur J Paediatr Neurol. 2023 Oct 14;47:105-109. doi: 10.1016/j.ejpn.2023.10.002. Online ahead of print.ABSTRACTDuchenne Muscular Dystrophy (DMD) is characterized by an initial increase in motor function followed by a plateau phase and then entering a phase of steady decline. However, motor evolution of DMD have not been evaluated in developing countries. Therefore, this study aims to evaluate the trajectory of motor function in a sample of Colombian children with DMD. We included 119 children with DMD aged 4.8-19.3 years (mean follow-up = 1.7 years). A linear mixed model was used with age as the time scale and adjusted for ...
Source: European Journal of Paediatric Neurology - October 19, 2023 Category: Neurology Authors: Fernando Ortiz-Corredor Andres Sandoval-Salcedo Sandra Castellar-Leones Diana Soto-Pena Edicson Ru íz-Ospina Fernando Suarez-Obando Source Type: research

"Somewhere to turn to with my questions": A pre-post pilot of an information linker service for caregivers who have a child with a Developmental and Epileptic Encephalopathy
CONCLUSION: Our study shows that GenE Compass is feasible with the appropriate allocation of resources and highly acceptable to caregivers who have a child with a DEE.PMID:37832466 | DOI:10.1016/j.ejpn.2023.09.010 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - October 13, 2023 Category: Neurology Authors: Eden G Robertson Natalie J Roberts Fleur Le Marne Erin Beavis Rebecca Macintosh Lauren Kelada Stephanie Best Ilias Goranitis Kristine Pierce Deepak Gill Rani Sachdev Ann Bye Elizabeth E Palmer Source Type: research

"Somewhere to turn to with my questions": A pre-post pilot of an information linker service for caregivers who have a child with a Developmental and Epileptic Encephalopathy
CONCLUSION: Our study shows that GenE Compass is feasible with the appropriate allocation of resources and highly acceptable to caregivers who have a child with a DEE.PMID:37832466 | DOI:10.1016/j.ejpn.2023.09.010 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - October 13, 2023 Category: Neurology Authors: Eden G Robertson Natalie J Roberts Fleur Le Marne Erin Beavis Rebecca Macintosh Lauren Kelada Stephanie Best Ilias Goranitis Kristine Pierce Deepak Gill Rani Sachdev Ann Bye Elizabeth E Palmer Source Type: research

"Somewhere to turn to with my questions": A pre-post pilot of an information linker service for caregivers who have a child with a Developmental and Epileptic Encephalopathy
CONCLUSION: Our study shows that GenE Compass is feasible with the appropriate allocation of resources and highly acceptable to caregivers who have a child with a DEE.PMID:37832466 | DOI:10.1016/j.ejpn.2023.09.010 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - October 13, 2023 Category: Neurology Authors: Eden G Robertson Natalie J Roberts Fleur Le Marne Erin Beavis Rebecca Macintosh Lauren Kelada Stephanie Best Ilias Goranitis Kristine Pierce Deepak Gill Rani Sachdev Ann Bye Elizabeth E Palmer Source Type: research