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Knowledge, awareness, and attitudes towards epilepsy among elementary schoolteachers in the Kingdom of Bahrain
CONCLUSION: The knowledge and attitudes of schoolteachers in Bahrain towards epilepsy are relatively good but with remaining improvement potential. They do not fully grasp all seizure types nor adequate first-aid measures promoting future epilepsy educational programs.PMID:37659186 | DOI:10.1016/j.ejpn.2023.08.001 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - September 2, 2023 Category: Neurology Authors: Alaa Elmazny Salman Alzayani Mohamed Hany Shehata Rehab Magdy Source Type: research

Pediatric myasthenia gravis with a combination of AChR and RyR is associated with an earlier onset and lower CSR rate: A cohort study in southwest China
CONCLUSIONS: We summarized one of the largest cohorts of pediatric MG patients and compared the clinical phenotype of patients with antibody-negative, AChR-positive, and AChR with or without titin and RyR antibodies. The results showed that patients with AChR and RyR antibodies had a younger onset age, a higher immunosuppressant use rate and a lower CSR rate.PMID:37639776 | DOI:10.1016/j.ejpn.2023.08.002 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - August 28, 2023 Category: Neurology Authors: Jie Liu Jiannan Ma Siqi Hong Li Jiang Tianyi Li Source Type: research

Gaboxadol in angelman syndrome: A double-blind, parallel-group, randomized placebo-controlled phase 3 study
CONCLUSIONS: There was no significant difference in CGI-I-AS between gaboxadol and placebo after 12 weeks of study treatment in pediatric AS participants.CLINICALTRIALS: GOV: NCT04106557.PMID:37639777 | DOI:10.1016/j.ejpn.2023.07.008 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - August 28, 2023 Category: Neurology Authors: Christopher Keary Lynne M Bird Marie-Claire de Wit Shivkumar Hatti Gali Heimer Helen Heussler Alexander Kolevzon Adera Mathews Cesar Ochoa-Lubinoff Wen-Hann Tan Ying Yan Maxwell Adams Source Type: research

Pediatric myasthenia gravis with a combination of AChR and RyR is associated with an earlier onset and lower CSR rate: A cohort study in southwest China
CONCLUSIONS: We summarized one of the largest cohorts of pediatric MG patients and compared the clinical phenotype of patients with antibody-negative, AChR-positive, and AChR with or without titin and RyR antibodies. The results showed that patients with AChR and RyR antibodies had a younger onset age, a higher immunosuppressant use rate and a lower CSR rate.PMID:37639776 | DOI:10.1016/j.ejpn.2023.08.002 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - August 28, 2023 Category: Neurology Authors: Jie Liu Jiannan Ma Siqi Hong Li Jiang Tianyi Li Source Type: research

Gaboxadol in angelman syndrome: A double-blind, parallel-group, randomized placebo-controlled phase 3 study
CONCLUSIONS: There was no significant difference in CGI-I-AS between gaboxadol and placebo after 12 weeks of study treatment in pediatric AS participants.CLINICALTRIALS: GOV: NCT04106557.PMID:37639777 | DOI:10.1016/j.ejpn.2023.07.008 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - August 28, 2023 Category: Neurology Authors: Christopher Keary Lynne M Bird Marie-Claire de Wit Shivkumar Hatti Gali Heimer Helen Heussler Alexander Kolevzon Adera Mathews Cesar Ochoa-Lubinoff Wen-Hann Tan Ying Yan Maxwell Adams Source Type: research

Pediatric myasthenia gravis with a combination of AChR and RyR is associated with an earlier onset and lower CSR rate: A cohort study in southwest China
CONCLUSIONS: We summarized one of the largest cohorts of pediatric MG patients and compared the clinical phenotype of patients with antibody-negative, AChR-positive, and AChR with or without titin and RyR antibodies. The results showed that patients with AChR and RyR antibodies had a younger onset age, a higher immunosuppressant use rate and a lower CSR rate.PMID:37639776 | DOI:10.1016/j.ejpn.2023.08.002 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - August 28, 2023 Category: Neurology Authors: Jie Liu Jiannan Ma Siqi Hong Li Jiang Tianyi Li Source Type: research

Gaboxadol in angelman syndrome: A double-blind, parallel-group, randomized placebo-controlled phase 3 study
CONCLUSIONS: There was no significant difference in CGI-I-AS between gaboxadol and placebo after 12 weeks of study treatment in pediatric AS participants.CLINICALTRIALS: GOV: NCT04106557.PMID:37639777 | DOI:10.1016/j.ejpn.2023.07.008 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - August 28, 2023 Category: Neurology Authors: Christopher Keary Lynne M Bird Marie-Claire de Wit Shivkumar Hatti Gali Heimer Helen Heussler Alexander Kolevzon Adera Mathews Cesar Ochoa-Lubinoff Wen-Hann Tan Ying Yan Maxwell Adams Source Type: research

Pediatric myasthenia gravis with a combination of AChR and RyR is associated with an earlier onset and lower CSR rate: A cohort study in southwest China
CONCLUSIONS: We summarized one of the largest cohorts of pediatric MG patients and compared the clinical phenotype of patients with antibody-negative, AChR-positive, and AChR with or without titin and RyR antibodies. The results showed that patients with AChR and RyR antibodies had a younger onset age, a higher immunosuppressant use rate and a lower CSR rate.PMID:37639776 | DOI:10.1016/j.ejpn.2023.08.002 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - August 28, 2023 Category: Neurology Authors: Jie Liu Jiannan Ma Siqi Hong Li Jiang Tianyi Li Source Type: research

Gaboxadol in angelman syndrome: A double-blind, parallel-group, randomized placebo-controlled phase 3 study
CONCLUSIONS: There was no significant difference in CGI-I-AS between gaboxadol and placebo after 12 weeks of study treatment in pediatric AS participants.CLINICALTRIALS: GOV: NCT04106557.PMID:37639777 | DOI:10.1016/j.ejpn.2023.07.008 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - August 28, 2023 Category: Neurology Authors: Christopher Keary Lynne M Bird Marie-Claire de Wit Shivkumar Hatti Gali Heimer Helen Heussler Alexander Kolevzon Adera Mathews Cesar Ochoa-Lubinoff Wen-Hann Tan Ying Yan Maxwell Adams Source Type: research

Development and testing of methods to record and follow up spells in patients with alternating hemiplegia of childhood
CONCLUSIONS: Video-library training improved spell identification. Calendar with weekly reviews resulted in a sustained and consistent record keeping. Caregivers' e-Diary feedback was encouraging with long-term usage in many. These approaches could be helpful for AHC and, potentially, in similar disorders.PMID:37562161 | DOI:10.1016/j.ejpn.2023.07.005 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - August 10, 2023 Category: Neurology Authors: Maria K Sentmanat Maria T Papadopoulou Lyndsey Prange Carmen Fons Elisa De Grandis Aikaterini Vezyroglou April Boggs Samantha Su Marion Comajuan Jeffrey Wuchich Sigur ður Jóhannesson Jennifer Anticona Huaynate Michela Stagnaro Andrey Megvinov Shital Pat Source Type: research

Development and testing of methods to record and follow up spells in patients with alternating hemiplegia of childhood
CONCLUSIONS: Video-library training improved spell identification. Calendar with weekly reviews resulted in a sustained and consistent record keeping. Caregivers' e-Diary feedback was encouraging with long-term usage in many. These approaches could be helpful for AHC and, potentially, in similar disorders.PMID:37562161 | DOI:10.1016/j.ejpn.2023.07.005 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - August 10, 2023 Category: Neurology Authors: Maria K Sentmanat Maria T Papadopoulou Lyndsey Prange Carmen Fons Elisa De Grandis Aikaterini Vezyroglou April Boggs Samantha Su Marion Comajuan Jeffrey Wuchich Sigur ður Jóhannesson Jennifer Anticona Huaynate Michela Stagnaro Andrey Megvinov Shital Pat Source Type: research

Development and testing of methods to record and follow up spells in patients with alternating hemiplegia of childhood
CONCLUSIONS: Video-library training improved spell identification. Calendar with weekly reviews resulted in a sustained and consistent record keeping. Caregivers' e-Diary feedback was encouraging with long-term usage in many. These approaches could be helpful for AHC and, potentially, in similar disorders.PMID:37562161 | DOI:10.1016/j.ejpn.2023.07.005 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - August 10, 2023 Category: Neurology Authors: Maria K Sentmanat Maria T Papadopoulou Lyndsey Prange Carmen Fons Elisa De Grandis Aikaterini Vezyroglou April Boggs Samantha Su Marion Comajuan Jeffrey Wuchich Sigur ður Jóhannesson Jennifer Anticona Huaynate Michela Stagnaro Andrey Megvinov Shital Pat Source Type: research

Development and testing of methods to record and follow up spells in patients with alternating hemiplegia of childhood
CONCLUSIONS: Video-library training improved spell identification. Calendar with weekly reviews resulted in a sustained and consistent record keeping. Caregivers' e-Diary feedback was encouraging with long-term usage in many. These approaches could be helpful for AHC and, potentially, in similar disorders.PMID:37562161 | DOI:10.1016/j.ejpn.2023.07.005 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - August 10, 2023 Category: Neurology Authors: Maria K Sentmanat Maria T Papadopoulou Lyndsey Prange Carmen Fons Elisa De Grandis Aikaterini Vezyroglou April Boggs Samantha Su Marion Comajuan Jeffrey Wuchich Sigur ður Jóhannesson Jennifer Anticona Huaynate Michela Stagnaro Andrey Megvinov Shital Pat Source Type: research

Development and testing of methods to record and follow up spells in patients with alternating hemiplegia of childhood
CONCLUSIONS: Video-library training improved spell identification. Calendar with weekly reviews resulted in a sustained and consistent record keeping. Caregivers' e-Diary feedback was encouraging with long-term usage in many. These approaches could be helpful for AHC and, potentially, in similar disorders.PMID:37562161 | DOI:10.1016/j.ejpn.2023.07.005 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - August 10, 2023 Category: Neurology Authors: Maria K Sentmanat Maria T Papadopoulou Lyndsey Prange Carmen Fons Elisa De Grandis Aikaterini Vezyroglou April Boggs Samantha Su Marion Comajuan Jeffrey Wuchich Sigur ður Jóhannesson Jennifer Anticona Huaynate Michela Stagnaro Andrey Megvinov Shital Pat Source Type: research

Development and testing of methods to record and follow up spells in patients with alternating hemiplegia of childhood
CONCLUSIONS: Video-library training improved spell identification. Calendar with weekly reviews resulted in a sustained and consistent record keeping. Caregivers' e-Diary feedback was encouraging with long-term usage in many. These approaches could be helpful for AHC and, potentially, in similar disorders.PMID:37562161 | DOI:10.1016/j.ejpn.2023.07.005 (Source: European Journal of Paediatric Neurology)
Source: European Journal of Paediatric Neurology - August 10, 2023 Category: Neurology Authors: Maria K Sentmanat Maria T Papadopoulou Lyndsey Prange Carmen Fons Elisa De Grandis Aikaterini Vezyroglou April Boggs Samantha Su Marion Comajuan Jeffrey Wuchich Sigur ður Jóhannesson Jennifer Anticona Huaynate Michela Stagnaro Andrey Megvinov Shital Pat Source Type: research