Adrenal venous sampling criteria for chemiluminescent enzyme immunoassay as a preferable alternative to radioimmunoassay in primary aldosteronism
This study examined PAC conversion in adrenal venous sampling (AVS) and AVS criteria when measured using chemiluminescent enzyme immunoassay (CLEIA). PAC of 415 adrenal venous blood samples from AVS (including segmental AVS) of 63 patients with primary aldosteronism was measured using RIA (Spac-S aldosterone kit; Fujirebio Inc.) and CLEIA (Lumipulse Presto Aldosterone; Fujirebio Inc.). PAC of 70 AVS samples was also measured using liquid chromatography-mass spectrometry (LC-MS/MS, ASKA Pharma Medical Co., Ltd.). PAC conversion formulas were determined for each AVS sample assay. PAC measured using CLEIA was significantly co...
Source: Endocrine Journal - February 28, 2024 Category: Endocrinology Authors: Kazuki Nakai Yuya Tsurutani Koki Irie Kyoko Teruyama Sachiko Suematsu Seishi Matsui Kohzoh Makita Jun Saito Masao Omura Tetsuo Nishikawa Source Type: research
Expression of SMADs in orthotopic human endometrium, ovarian endometriosis, and endometriotic lesions in a murine model
In conclusion, these results suggest that activin A activates the SMAD signaling pathway and promotes the development of endometriotic lesions, thus identifying SMAD7 as a potential therapeutic target for endometriosis.PMID:38417880 | DOI:10.1507/endocrj.EJ23-0486 (Source: Endocrine Journal)
Source: Endocrine Journal - February 28, 2024 Category: Endocrinology Authors: Yuri Kadota Takeshi Kato Kana Kasai Takako Kawakita Misaki Murayama Akari Shinya Hikari Sasada Sachiko Katayama Mari Nii Shota Yamamoto Hiroki Noguchi Kou Tamura Hidenori Aoki Miyu Taniguchi Tomotaka Nakagawa Takashi Kaji Masato Nishimura Riyo Kinouchi Ka Source Type: research
My career in endocrinology and outstanding neuroendocrinologists we collaborated
Endocr J. 2024;71(2):83-88. doi: 10.1507/endocrj.EJ20230816.NO ABSTRACTPMID:38417871 | DOI:10.1507/endocrj.EJ20230816 (Source: Endocrine Journal)
Source: Endocrine Journal - February 28, 2024 Category: Endocrinology Authors: Kozo Hashimoto Source Type: research
Adrenal venous sampling criteria for chemiluminescent enzyme immunoassay as a preferable alternative to radioimmunoassay in primary aldosteronism
This study examined PAC conversion in adrenal venous sampling (AVS) and AVS criteria when measured using chemiluminescent enzyme immunoassay (CLEIA). PAC of 415 adrenal venous blood samples from AVS (including segmental AVS) of 63 patients with primary aldosteronism was measured using RIA (Spac-S aldosterone kit; Fujirebio Inc.) and CLEIA (Lumipulse Presto Aldosterone; Fujirebio Inc.). PAC of 70 AVS samples was also measured using liquid chromatography-mass spectrometry (LC-MS/MS, ASKA Pharma Medical Co., Ltd.). PAC conversion formulas were determined for each AVS sample assay. PAC measured using CLEIA was significantly co...
Source: Endocrine Journal - February 28, 2024 Category: Endocrinology Authors: Kazuki Nakai Yuya Tsurutani Koki Irie Kyoko Teruyama Sachiko Suematsu Seishi Matsui Kohzoh Makita Jun Saito Masao Omura Tetsuo Nishikawa Source Type: research
Expression of SMADs in orthotopic human endometrium, ovarian endometriosis, and endometriotic lesions in a murine model
In conclusion, these results suggest that activin A activates the SMAD signaling pathway and promotes the development of endometriotic lesions, thus identifying SMAD7 as a potential therapeutic target for endometriosis.PMID:38417880 | DOI:10.1507/endocrj.EJ23-0486 (Source: Endocrine Journal)
Source: Endocrine Journal - February 28, 2024 Category: Endocrinology Authors: Yuri Kadota Takeshi Kato Kana Kasai Takako Kawakita Misaki Murayama Akari Shinya Hikari Sasada Sachiko Katayama Mari Nii Shota Yamamoto Hiroki Noguchi Kou Tamura Hidenori Aoki Miyu Taniguchi Tomotaka Nakagawa Takashi Kaji Masato Nishimura Riyo Kinouchi Ka Source Type: research
Positive association between the proinsulin-to-C-peptide ratio and prolonged hyperglycemic time in type 2 diabetes
Endocr J. 2024 Feb 23. doi: 10.1507/endocrj.EJ23-0525. Online ahead of print.ABSTRACTThe proinsulin-to-C-peptide (PI:C) ratio is an index applied during the early stage of pancreatic β-cell dysfunction. The aim of this study was to identify the characteristics associated with the PI:C ratio to discuss pancreatic β-cell dysfunction progression during the natural course of type 2 diabetes and its relationship with glycemic management. This multicenter, prospective observational study included 272 outpatients with type 2 diabetes. Continuous glucose monitoring was performed and fasting blood samples were collected and analy...
Source: Endocrine Journal - February 25, 2024 Category: Endocrinology Authors: Aika Miya Akinobu Nakamura Hiroshi Nomoto Hiraku Kameda Tatsuya Atsumi Source Type: research
Prevalence of thyroid diffuse goiter and its association with body mass index and the presence of cysts and nodules in children and adolescents: the Fukushima Health Management Survey
Endocr J. 2024 Feb 16. doi: 10.1507/endocrj.EJ23-0609. Online ahead of print.ABSTRACTThe main cause of diffuse thyroid goiter is autoimmune chronic thyroiditis, otherwise known as Hashimoto's thyroiditis. Thyroid hormones play pivotal roles in growth and development during childhood. However, the prevalence of diffuse goiter and the relationships between diffuse goiter, thyroid volume, cysts and nodules, and anthropometric measurements in children are not well known. Among 789,459 participants who participated in thyroid ultrasound examinations, 320,206 participants (male: 161,728; female: 158,478) aged 1-23 years were ana...
Source: Endocrine Journal - February 18, 2024 Category: Endocrinology Authors: Nana Nakahata Mahiro Asano Norikazu Abe Haruka Ejiri Hisashi Ota Satoshi Suzuki Ayako Sato Rina Tazaki Natsuki Nagamine Chisato Takahashi Yukie Yamaya Manabu Iwadate Takashi Matsuzuka Tetsuya Ohira Seiji Yasumura Satoru Suzuki Fumihiko Furuya Hiroki Shimu Source Type: research
Lipopolysaccharide inhibits osteoblast formation and receptor activator of nuclear factor- κB ligand degradation via autophagy inhibition
In conclusion, LPS can inhibit autophagy in osteoblast precursors, thereby inhibiting osteoblast formation and RANKL autophagic degradation.PMID:38355125 | DOI:10.1507/endocrj.EJ23-0484 (Source: Endocrine Journal)
Source: Endocrine Journal - February 14, 2024 Category: Endocrinology Authors: Huaizhi Zhang Jianhua Lin Xu Chen Jianhui Dai Haibin Lin Source Type: research
