Essay: Endocrinology and my research life
Endocr J. 2023;70(11):1029-1034. doi: 10.1507/endocrj.EJ20230622.NO ABSTRACTPMID:38030234 | DOI:10.1507/endocrj.EJ20230622 (Source: Endocrine Journal)
Source: Endocrine Journal - November 29, 2023 Category: Endocrinology Authors: Toshio Ogihara Source Type: research

Correlation between plasma glutamate and adiponectin in patients with type 2 diabetes
Endocr J. 2023 Nov 28. doi: 10.1507/endocrj.EJ23-0506. Online ahead of print.ABSTRACTVisceral fat accumulation is a major determinant of type 2 diabetes mellitus and cardiovascular diseases. Recent studies have reported that glutamate is the most elevated amino acid in the plasma amino acid profile in patients with obesity and/or visceral fat accumulation. Here, we show the relationship between plasma glutamate and the clinical features of patients with type 2 diabetes. The study subjects were 62 (28 men and 34 women) Japanese patients with type 2 diabetes. Blood profiles, including glutamate and adiponectin (APN) levels a...
Source: Endocrine Journal - November 29, 2023 Category: Endocrinology Authors: Hirofumi Nagao Hitoshi Nishizawa Shiro Fukuda Yuya Fujishima Shunbun Kita Norikazu Maeda Takeshi Bamba Eiichiro Fukusaki Iichiro Shimomura Source Type: research

Analysis of five cases showing false-high Hemoglobin A1c due to reduced catalase activity
Endocr J. 2023 Nov 28. doi: 10.1507/endocrj.EJ23-0212. Online ahead of print.ABSTRACTWe encountered five cases that exhibited false-high Hemoglobin A1c (HbA1c) levels when samples were examined using the enzyme-based NORUDIA N HbA1c kit. HbA1c levels were higher than those obtained using other methods, such as HPLC, immune-based methods, and other enzyme-based kits. This kit produced inaccurate results for HbA1c when residual peroxides were present in samples. The addition of peroxidase solution restored false-high HbA1c levels in the five cases, indicating that reduced catalase activity was responsible for these values be...
Source: Endocrine Journal - November 29, 2023 Category: Endocrinology Authors: Kenji Hara Atsushi Ujiie Shiori Suzuki Takenori Okumura Mio Kubo Hiroyuki Shinozaki Mototaka Yamauchi Takafumi Tsuchiya Kohzo Takebayashi Nobuyuki Shimozawa Masafumi Koga Koshi Hashimoto Source Type: research

Essay: Endocrinology and my research life
Endocr J. 2023;70(11):1029-1034. doi: 10.1507/endocrj.EJ20230622.NO ABSTRACTPMID:38030234 | DOI:10.1507/endocrj.EJ20230622 (Source: Endocrine Journal)
Source: Endocrine Journal - November 29, 2023 Category: Endocrinology Authors: Toshio Ogihara Source Type: research

Correlation between plasma glutamate and adiponectin in patients with type 2 diabetes
Endocr J. 2023 Nov 28. doi: 10.1507/endocrj.EJ23-0506. Online ahead of print.ABSTRACTVisceral fat accumulation is a major determinant of type 2 diabetes mellitus and cardiovascular diseases. Recent studies have reported that glutamate is the most elevated amino acid in the plasma amino acid profile in patients with obesity and/or visceral fat accumulation. Here, we show the relationship between plasma glutamate and the clinical features of patients with type 2 diabetes. The study subjects were 62 (28 men and 34 women) Japanese patients with type 2 diabetes. Blood profiles, including glutamate and adiponectin (APN) levels a...
Source: Endocrine Journal - November 29, 2023 Category: Endocrinology Authors: Hirofumi Nagao Hitoshi Nishizawa Shiro Fukuda Yuya Fujishima Shunbun Kita Norikazu Maeda Takeshi Bamba Eiichiro Fukusaki Iichiro Shimomura Source Type: research

Analysis of five cases showing false-high Hemoglobin A1c due to reduced catalase activity
Endocr J. 2023 Nov 28. doi: 10.1507/endocrj.EJ23-0212. Online ahead of print.ABSTRACTWe encountered five cases that exhibited false-high Hemoglobin A1c (HbA1c) levels when samples were examined using the enzyme-based NORUDIA N HbA1c kit. HbA1c levels were higher than those obtained using other methods, such as HPLC, immune-based methods, and other enzyme-based kits. This kit produced inaccurate results for HbA1c when residual peroxides were present in samples. The addition of peroxidase solution restored false-high HbA1c levels in the five cases, indicating that reduced catalase activity was responsible for these values be...
Source: Endocrine Journal - November 29, 2023 Category: Endocrinology Authors: Kenji Hara Atsushi Ujiie Shiori Suzuki Takenori Okumura Mio Kubo Hiroyuki Shinozaki Mototaka Yamauchi Takafumi Tsuchiya Kohzo Takebayashi Nobuyuki Shimozawa Masafumi Koga Koshi Hashimoto Source Type: research

Essay: Endocrinology and my research life
Endocr J. 2023;70(11):1029-1034. doi: 10.1507/endocrj.EJ20230622.NO ABSTRACTPMID:38030234 | DOI:10.1507/endocrj.EJ20230622 (Source: Endocrine Journal)
Source: Endocrine Journal - November 29, 2023 Category: Endocrinology Authors: Toshio Ogihara Source Type: research

Correlation between plasma glutamate and adiponectin in patients with type 2 diabetes
Endocr J. 2023 Nov 28. doi: 10.1507/endocrj.EJ23-0506. Online ahead of print.ABSTRACTVisceral fat accumulation is a major determinant of type 2 diabetes mellitus and cardiovascular diseases. Recent studies have reported that glutamate is the most elevated amino acid in the plasma amino acid profile in patients with obesity and/or visceral fat accumulation. Here, we show the relationship between plasma glutamate and the clinical features of patients with type 2 diabetes. The study subjects were 62 (28 men and 34 women) Japanese patients with type 2 diabetes. Blood profiles, including glutamate and adiponectin (APN) levels a...
Source: Endocrine Journal - November 29, 2023 Category: Endocrinology Authors: Hirofumi Nagao Hitoshi Nishizawa Shiro Fukuda Yuya Fujishima Shunbun Kita Norikazu Maeda Takeshi Bamba Eiichiro Fukusaki Iichiro Shimomura Source Type: research

Analysis of five cases showing false-high Hemoglobin A1c due to reduced catalase activity
Endocr J. 2023 Nov 28. doi: 10.1507/endocrj.EJ23-0212. Online ahead of print.ABSTRACTWe encountered five cases that exhibited false-high Hemoglobin A1c (HbA1c) levels when samples were examined using the enzyme-based NORUDIA N HbA1c kit. HbA1c levels were higher than those obtained using other methods, such as HPLC, immune-based methods, and other enzyme-based kits. This kit produced inaccurate results for HbA1c when residual peroxides were present in samples. The addition of peroxidase solution restored false-high HbA1c levels in the five cases, indicating that reduced catalase activity was responsible for these values be...
Source: Endocrine Journal - November 29, 2023 Category: Endocrinology Authors: Kenji Hara Atsushi Ujiie Shiori Suzuki Takenori Okumura Mio Kubo Hiroyuki Shinozaki Mototaka Yamauchi Takafumi Tsuchiya Kohzo Takebayashi Nobuyuki Shimozawa Masafumi Koga Koshi Hashimoto Source Type: research

Essay: Endocrinology and my research life
Endocr J. 2023;70(11):1029-1034. doi: 10.1507/endocrj.EJ20230622.NO ABSTRACTPMID:38030234 | DOI:10.1507/endocrj.EJ20230622 (Source: Endocrine Journal)
Source: Endocrine Journal - November 29, 2023 Category: Endocrinology Authors: Toshio Ogihara Source Type: research

Correlation between plasma glutamate and adiponectin in patients with type 2 diabetes
Endocr J. 2023 Nov 28. doi: 10.1507/endocrj.EJ23-0506. Online ahead of print.ABSTRACTVisceral fat accumulation is a major determinant of type 2 diabetes mellitus and cardiovascular diseases. Recent studies have reported that glutamate is the most elevated amino acid in the plasma amino acid profile in patients with obesity and/or visceral fat accumulation. Here, we show the relationship between plasma glutamate and the clinical features of patients with type 2 diabetes. The study subjects were 62 (28 men and 34 women) Japanese patients with type 2 diabetes. Blood profiles, including glutamate and adiponectin (APN) levels a...
Source: Endocrine Journal - November 29, 2023 Category: Endocrinology Authors: Hirofumi Nagao Hitoshi Nishizawa Shiro Fukuda Yuya Fujishima Shunbun Kita Norikazu Maeda Takeshi Bamba Eiichiro Fukusaki Iichiro Shimomura Source Type: research

Analysis of five cases showing false-high Hemoglobin A1c due to reduced catalase activity
Endocr J. 2023 Nov 28. doi: 10.1507/endocrj.EJ23-0212. Online ahead of print.ABSTRACTWe encountered five cases that exhibited false-high Hemoglobin A1c (HbA1c) levels when samples were examined using the enzyme-based NORUDIA N HbA1c kit. HbA1c levels were higher than those obtained using other methods, such as HPLC, immune-based methods, and other enzyme-based kits. This kit produced inaccurate results for HbA1c when residual peroxides were present in samples. The addition of peroxidase solution restored false-high HbA1c levels in the five cases, indicating that reduced catalase activity was responsible for these values be...
Source: Endocrine Journal - November 29, 2023 Category: Endocrinology Authors: Kenji Hara Atsushi Ujiie Shiori Suzuki Takenori Okumura Mio Kubo Hiroyuki Shinozaki Mototaka Yamauchi Takafumi Tsuchiya Kohzo Takebayashi Nobuyuki Shimozawa Masafumi Koga Koshi Hashimoto Source Type: research