Lung adenocarcinoma metastasis within a pituitary neuroendocrine tumor: a case report with review of literature
Endocr J. 2023 Dec 29. doi: 10.1507/endocrj.EJ23-0372. Online ahead of print.ABSTRACTCollision tumors involving the metastasis of malignant neoplasms to pituitary neuroendocrine tumors (PitNETs) are extremely rare. We herein report a case involving a patient with lung adenocarcinoma metastasis within a PitNET who exhibited relatively rapid progression of neurological symptoms. A 75-year-old man who underwent tumor resection 36 and 18 years prior to presentation for bladder and colon cancer, respectively, without recurrence presented with bitemporal hemianopsia, ptosis, and diplopia of the right eye. Subsequent magnetic res...
Source: Endocrine Journal - January 3, 2024 Category: Endocrinology Authors: Koji Suzuki Shigeyuki Tahara Yujiro Hattori Shinichiro Teramoto Eitaro Ishisaka Chie Inomoto Robert Yoshiyuki Osamura Akio Morita Yasuo Murai Source Type: research
Reminiscences of my life as an endocrine researcher
Endocr J. 2023;70(12):1109-1111. doi: 10.1507/endocrj.EJ20230627.NO ABSTRACTPMID:38171802 | DOI:10.1507/endocrj.EJ20230627 (Source: Endocrine Journal)
Source: Endocrine Journal - January 3, 2024 Category: Endocrinology Authors: Toshihiro Suda Source Type: research
Erratum
Endocr J. 2023;70(12):1207. doi: 10.1507/endocrj.EJ70-12_Erratum.NO ABSTRACTPMID:38171803 | DOI:10.1507/endocrj.EJ70-12_Erratum (Source: Endocrine Journal)
Source: Endocrine Journal - January 3, 2024 Category: Endocrinology Source Type: research
Effects of laparoscopic sleeve gastrectomy on nonalcoholic fatty liver disease and TGF- β signaling pathway
This study enrolled 36 severely obese patients who underwent LSG at our hospital from January 2020 to April 2022. As a pilot study, proteomic analysis was conducted on six patients using serum collected before and at 6 months after LSG, and significantly fluctuating proteins were extracted. Subsequently, verification by enzyme-linked immunosorbent assay (ELISA) using collected serum was performed on the remaining 30 patients. The mean weight of enrolled patients was 118.5 kg. Proteomic analysis identified 1,912 proteins, many of which were related to the TGF-β signaling pathway. Among these proteins, we focused on five TG...
Source: Endocrine Journal - January 3, 2024 Category: Endocrinology Authors: Hideki Kumagai Akira Sasaki Akira Umemura Keisuke Kakisaka Takeshi Iwaya Satoshi S Nishizuka Source Type: research
Inhibitory effects of estetrol on the invasion and migration of immortalized human endometrial stromal cells
Endocr J. 2023 Dec 28. doi: 10.1507/endocrj.EJ23-0397. Online ahead of print.ABSTRACTEndometriosis, a common gynecological disorder characterized by the growth of endometrial gland and stroma outside the uterus, causes several symptoms such as dysmenorrhea, hypermenorrhea, and chronic abdominal pain. 17β estradiol (E2) stimulates the growth of endometriotic lesions. Although estetrol (E4), produced by human fetal liver, is also a natural estrogen, it may have the opposite effects on endometriotic cells. We investigated different effects of E4 and E2 on the invasion and migration of immortalized human endometrial stromal c...
Source: Endocrine Journal - January 3, 2024 Category: Endocrinology Authors: Akihiko Wakatsuki Yinzhi Lin Shiori Kojima Hiroshi Matsushita Kosei Takeuchi Kazuo Umezawa Source Type: research
Lung adenocarcinoma metastasis within a pituitary neuroendocrine tumor: a case report with review of literature
Endocr J. 2023 Dec 29. doi: 10.1507/endocrj.EJ23-0372. Online ahead of print.ABSTRACTCollision tumors involving the metastasis of malignant neoplasms to pituitary neuroendocrine tumors (PitNETs) are extremely rare. We herein report a case involving a patient with lung adenocarcinoma metastasis within a PitNET who exhibited relatively rapid progression of neurological symptoms. A 75-year-old man who underwent tumor resection 36 and 18 years prior to presentation for bladder and colon cancer, respectively, without recurrence presented with bitemporal hemianopsia, ptosis, and diplopia of the right eye. Subsequent magnetic res...
Source: Endocrine Journal - January 3, 2024 Category: Endocrinology Authors: Koji Suzuki Shigeyuki Tahara Yujiro Hattori Shinichiro Teramoto Eitaro Ishisaka Chie Inomoto Robert Yoshiyuki Osamura Akio Morita Yasuo Murai Source Type: research
Reminiscences of my life as an endocrine researcher
Endocr J. 2023;70(12):1109-1111. doi: 10.1507/endocrj.EJ20230627.NO ABSTRACTPMID:38171802 | DOI:10.1507/endocrj.EJ20230627 (Source: Endocrine Journal)
Source: Endocrine Journal - January 3, 2024 Category: Endocrinology Authors: Toshihiro Suda Source Type: research
Erratum
Endocr J. 2023;70(12):1207. doi: 10.1507/endocrj.EJ70-12_Erratum.NO ABSTRACTPMID:38171803 | DOI:10.1507/endocrj.EJ70-12_Erratum (Source: Endocrine Journal)
Source: Endocrine Journal - January 3, 2024 Category: Endocrinology Source Type: research
Effects of laparoscopic sleeve gastrectomy on nonalcoholic fatty liver disease and TGF- β signaling pathway
This study enrolled 36 severely obese patients who underwent LSG at our hospital from January 2020 to April 2022. As a pilot study, proteomic analysis was conducted on six patients using serum collected before and at 6 months after LSG, and significantly fluctuating proteins were extracted. Subsequently, verification by enzyme-linked immunosorbent assay (ELISA) using collected serum was performed on the remaining 30 patients. The mean weight of enrolled patients was 118.5 kg. Proteomic analysis identified 1,912 proteins, many of which were related to the TGF-β signaling pathway. Among these proteins, we focused on five TG...
Source: Endocrine Journal - January 3, 2024 Category: Endocrinology Authors: Hideki Kumagai Akira Sasaki Akira Umemura Keisuke Kakisaka Takeshi Iwaya Satoshi S Nishizuka Source Type: research
Inhibitory effects of estetrol on the invasion and migration of immortalized human endometrial stromal cells
Endocr J. 2023 Dec 28. doi: 10.1507/endocrj.EJ23-0397. Online ahead of print.ABSTRACTEndometriosis, a common gynecological disorder characterized by the growth of endometrial gland and stroma outside the uterus, causes several symptoms such as dysmenorrhea, hypermenorrhea, and chronic abdominal pain. 17β estradiol (E2) stimulates the growth of endometriotic lesions. Although estetrol (E4), produced by human fetal liver, is also a natural estrogen, it may have the opposite effects on endometriotic cells. We investigated different effects of E4 and E2 on the invasion and migration of immortalized human endometrial stromal c...
Source: Endocrine Journal - January 3, 2024 Category: Endocrinology Authors: Akihiko Wakatsuki Yinzhi Lin Shiori Kojima Hiroshi Matsushita Kosei Takeuchi Kazuo Umezawa Source Type: research
Encapsulated human islets in alginate fiber maintain long-term functionality
Endocr J. 2023 Dec 22. doi: 10.1507/endocrj.EJ23-0474. Online ahead of print.ABSTRACTMaintenance of islet function after in vitro culture is crucial for both transplantation and research. Here we evaluated the effects of encapsulation in alginate fiber on the function of human islets which were distributed by the Alberta Islet Distribution Program. Encapsulated human islets from 15 deceased donors were cultured under 5.5 or 25 mM glucose conditions in vitro. The amounts of C-peptide and glucagon secreted from encapsulated islets into the culture media were measured periodically, and immunohistochemical studies were perform...
Source: Endocrine Journal - December 24, 2023 Category: Endocrinology Authors: Junko Nishida Takahiro Tsuno Shigeharu G Yabe Tatsuya Kin Satsuki Fukuda Fujie Takeda Jun Shirakawa Hitoshi Okochi Source Type: research
Epigenetic alterations of 11beta-hydroxysteroid dehydrogenase 1 gene in the adipose tissue of patients with primary aldosteronism
We examined the mRNA level and methylation status of the HSD11B1 promoter region in the adipose tissue of patients with primary aldosteronism (PA). We compared 10 tissue specimens from patients with PA caused by aldosterone-producing adenoma (APA) with 8 adipose tissue specimens from patients with subclinical Cushing's syndrome (SCS) caused by cortisol-producing adenomas, 4 tissue specimens from patients with Cushing's adenoma (Cu), or 7 tissue specimens from patients with non-functioning adrenal adenoma (NFA). PA, SCS, and Cu were diagnosed according to the guideline of the Japan Endocrine Society. The mRNA level of HSD11...
Source: Endocrine Journal - December 24, 2023 Category: Endocrinology Authors: Yoshimichi Takeda Masashi Demura Mitsuhiro Kometani Shigehiro Karashima Daisuke Aono Seigo Konishi Shin-Ichi Horike Makiko Meguro-Horike Takashi Yoneda Yoshiyu Takeda Source Type: research
Encapsulated human islets in alginate fiber maintain long-term functionality
Endocr J. 2023 Dec 22. doi: 10.1507/endocrj.EJ23-0474. Online ahead of print.ABSTRACTMaintenance of islet function after in vitro culture is crucial for both transplantation and research. Here we evaluated the effects of encapsulation in alginate fiber on the function of human islets which were distributed by the Alberta Islet Distribution Program. Encapsulated human islets from 15 deceased donors were cultured under 5.5 or 25 mM glucose conditions in vitro. The amounts of C-peptide and glucagon secreted from encapsulated islets into the culture media were measured periodically, and immunohistochemical studies were perform...
Source: Endocrine Journal - December 24, 2023 Category: Endocrinology Authors: Junko Nishida Takahiro Tsuno Shigeharu G Yabe Tatsuya Kin Satsuki Fukuda Fujie Takeda Jun Shirakawa Hitoshi Okochi Source Type: research
Epigenetic alterations of 11beta-hydroxysteroid dehydrogenase 1 gene in the adipose tissue of patients with primary aldosteronism
We examined the mRNA level and methylation status of the HSD11B1 promoter region in the adipose tissue of patients with primary aldosteronism (PA). We compared 10 tissue specimens from patients with PA caused by aldosterone-producing adenoma (APA) with 8 adipose tissue specimens from patients with subclinical Cushing's syndrome (SCS) caused by cortisol-producing adenomas, 4 tissue specimens from patients with Cushing's adenoma (Cu), or 7 tissue specimens from patients with non-functioning adrenal adenoma (NFA). PA, SCS, and Cu were diagnosed according to the guideline of the Japan Endocrine Society. The mRNA level of HSD11...
Source: Endocrine Journal - December 24, 2023 Category: Endocrinology Authors: Yoshimichi Takeda Masashi Demura Mitsuhiro Kometani Shigehiro Karashima Daisuke Aono Seigo Konishi Shin-Ichi Horike Makiko Meguro-Horike Takashi Yoneda Yoshiyu Takeda Source Type: research
Encapsulated human islets in alginate fiber maintain long-term functionality
Endocr J. 2023 Dec 22. doi: 10.1507/endocrj.EJ23-0474. Online ahead of print.ABSTRACTMaintenance of islet function after in vitro culture is crucial for both transplantation and research. Here we evaluated the effects of encapsulation in alginate fiber on the function of human islets which were distributed by the Alberta Islet Distribution Program. Encapsulated human islets from 15 deceased donors were cultured under 5.5 or 25 mM glucose conditions in vitro. The amounts of C-peptide and glucagon secreted from encapsulated islets into the culture media were measured periodically, and immunohistochemical studies were perform...
Source: Endocrine Journal - December 24, 2023 Category: Endocrinology Authors: Junko Nishida Takahiro Tsuno Shigeharu G Yabe Tatsuya Kin Satsuki Fukuda Fujie Takeda Jun Shirakawa Hitoshi Okochi Source Type: research
