Letter to the Editor Regarding: Spesolimab Efficacy and Safety in Patients with Moderate-to-Severe Palmoplantar Pustulosis: A Multicentre, Double-Blind, Randomised, Placebo-Controlled, Phase IIb, Dose-Finding Study
(Source: Dermatology and Therapy)
Source: Dermatology and Therapy - April 9, 2024 Category: Dermatology Source Type: research
Publisher Correction to: Real-World Effectiveness of Dupilumab in Adult and Adolescent Patients with Atopic Dermatitis: 2-Year Interim Data from the PROSE Registry
(Source: Dermatology and Therapy)
Source: Dermatology and Therapy - April 9, 2024 Category: Dermatology Source Type: research
Psoriasis and Molecular Target Therapies: Evidence of Efficacy in Preventing Cardiovascular Comorbidities
AbstractPsoriasis is now considered a systemic disease, and several comorbidities have been described such as cardiovascular diseases, neurologic and psychiatric disorders, chronic inflammatory bowel disease, psoriatic arthritis, etc. Regarding cardiovascular comorbidities, major adverse cardiovascular events have been reported in psoriasis patients by multiple epidemiologic studies. Moreover, smoking, obesity, metabolic syndrome, hypertension, dyslipidemia, diabetes and reduced physical activity are associated with psoriasis, increasing cardiovascular risk. Consequently, several aspects should be considered when making th...
Source: Dermatology and Therapy - April 9, 2024 Category: Dermatology Source Type: research
Clinical Characteristics and Therapeutic Aspects of Blaschko Linear Psoriasis
ConclusionThis study analyzed the clinical characteristics and therapeutic aspects of BLP. Compared with published studies, we have new findings, such as gender bias. Besides traditional antipsoriatic treatment, a personalized selection of biologics may also be a promising choice. Dermatologists should recognize and understand the significance of this disease, and provide patients with appropriate psychological counseling and clinical treatments. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - April 5, 2024 Category: Dermatology Source Type: research
Response to: Letter to Editor Regarding “Spesolimab Efficacy and Safety in Patients with Moderate-to-Severe Palmoplantar Pustulosis: A Multicentre, Double-Blind, Randomised, Placebo-Controlled, Phase IIb, Dose-Finding Study”
(Source: Dermatology and Therapy)
Source: Dermatology and Therapy - April 5, 2024 Category: Dermatology Source Type: research
Clinical Characteristics and Therapeutic Aspects of Blaschko Linear Psoriasis
ConclusionThis study analyzed the clinical characteristics and therapeutic aspects of BLP. Compared with published studies, we have new findings, such as gender bias. Besides traditional antipsoriatic treatment, a personalized selection of biologics may also be a promising choice. Dermatologists should recognize and understand the significance of this disease, and provide patients with appropriate psychological counseling and clinical treatments. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - April 5, 2024 Category: Dermatology Source Type: research
Response to: Letter to Editor Regarding “Spesolimab Efficacy and Safety in Patients with Moderate-to-Severe Palmoplantar Pustulosis: A Multicentre, Double-Blind, Randomised, Placebo-Controlled, Phase IIb, Dose-Finding Study”
(Source: Dermatology and Therapy)
Source: Dermatology and Therapy - April 5, 2024 Category: Dermatology Source Type: research
Improvements in Psoriasis-Related Work Productivity with Tildrakizumab: Results from a Phase 4 Real-World Study in Patients with Moderate-to-Severe Plaque Psoriasis
ConclusionTildrakizumab treatment mitigated work productivity loss due to psoriasis as measured by the presenteeism, total activity impairment, and total work productivity impairment domains of the WPAI:PSO.Trial RegistrationClinicalTrials.gov identifier, NCT03718299. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - April 4, 2024 Category: Dermatology Source Type: research
Acute Systemic Toxicity Caused by Topical Application of EMLA Cream on a Leg Ulcer: Case Report and Review of Literature
ConclusionEMLA cream may cause severe systemic toxicity even in adults under certain conditions, for example, when applied on damaged skin or in extensive amounts. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - April 3, 2024 Category: Dermatology Source Type: research
Utilising SNP Association Analysis as a Prospective Approach for Personalising Androgenetic Alopecia Treatment
ConclusionsThe study establishes a preliminary association between eight specific SNPs and AGA. These genetic markers offer insights into the variability of therapeutic responses, thus underlining the importance of personalised treatment approaches. Our findings show the potential for more targeted research to understand these SNPs ’ and further roles in AGA pathophysiology and in modulating treatment response. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - March 31, 2024 Category: Dermatology Source Type: research
Maintenance of Investigator ’s Static Global Assessment Response with Once-Daily Crisaborole in Participants with Mild to Moderate Atopic Dermatitis
ConclusionsAdult and pediatric participants with mild to moderate AD at baseline who had achieved responder criteria (treatment success) with crisaborole BID during the run-in period maintained response per ISGA with crisaborole QD during the double-blind maintenance period through week 52.Trial RegistrationClinicalTrials.gov: NCT04040192. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - March 28, 2024 Category: Dermatology Source Type: research
