Application and Comparison of Dermoscopy and Reflectance Confocal Microscopy in the Target Treatment of Genital Lichen Sclerosus: A Single-Arm Prospective Study
ConclusionBoth dermoscopy and RCM can be useful and non-invasive adjuvant tools for the evaluation and therapeutic monitoring of GLS. We recommended white structureless areas under dermoscopy and inflammatory cells count under RCM as variables for dermatologic imaging evaluation for GLS. Baricitinib is effective and safe for GLS, while randomized controlled trials are warranted. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - October 15, 2023 Category: Dermatology Source Type: research
Trifarotene Reduces Risk for Atrophic Acne Scars: Results from A Phase 4 Controlled Study
ConclusionsTrifarotene was effective and well tolerated in treating moderate-to-severe facial acne and reducing atrophic acne scars, with reduction of total atrophic scar count as early as week 2.Trial RegistrationClinicaltrials.gov NCT04856904. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - October 15, 2023 Category: Dermatology Source Type: research
Application and Comparison of Dermoscopy and Reflectance Confocal Microscopy in the Target Treatment of Genital Lichen Sclerosus: A Single-Arm Prospective Study
ConclusionBoth dermoscopy and RCM can be useful and non-invasive adjuvant tools for the evaluation and therapeutic monitoring of GLS. We recommended white structureless areas under dermoscopy and inflammatory cells count under RCM as variables for dermatologic imaging evaluation for GLS. Baricitinib is effective and safe for GLS, while randomized controlled trials are warranted. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - October 15, 2023 Category: Dermatology Source Type: research
Trifarotene Reduces Risk for Atrophic Acne Scars: Results from A Phase 4 Controlled Study
ConclusionsTrifarotene was effective and well tolerated in treating moderate-to-severe facial acne and reducing atrophic acne scars, with reduction of total atrophic scar count as early as week 2.Trial RegistrationClinicaltrials.gov NCT04856904. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - October 15, 2023 Category: Dermatology Source Type: research
Efficacy of Av ène Hydrotherapy on Chronic Pruritus in Patients with Plaque Psoriasis
ConclusionsThese findings demonstrated an immediate and long-lasting improvement of pruritus in patients with psoriasis who underwent Av ène thermal spring water hydrotherapy, indicating that this would be a good complementary therapy in the management of this disease.Trial RegistrationNCT03023254. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - October 14, 2023 Category: Dermatology Source Type: research
Microneedling with a Novel, n-3-PUFA-Rich Formulation Accelerates Inflammation Resolution to Improve Skin Recovery Outcomes in Adults with Healthy Skin
ConclusionThese data provide new evidence for the role of a novel multiple-active-ingredient formulation for improving skin outcomes up to 28 days following microneedling in adults with healthy skin when compared with a hyaluronic acid serum. The n-3 PUFA content of this formulation may drive accelerated inflammation resolution and wound healing alongside the complementary action of the other active ingredients, leading to the observed improvements in erythema, luminosity and skin texture. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - October 14, 2023 Category: Dermatology Source Type: research
Efficacy of Av ène Hydrotherapy on Chronic Pruritus in Patients with Plaque Psoriasis
ConclusionsThese findings demonstrated an immediate and long-lasting improvement of pruritus in patients with psoriasis who underwent Av ène thermal spring water hydrotherapy, indicating that this would be a good complementary therapy in the management of this disease.Trial RegistrationNCT03023254. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - October 14, 2023 Category: Dermatology Source Type: research
Microneedling with a Novel, n-3-PUFA-Rich Formulation Accelerates Inflammation Resolution to Improve Skin Recovery Outcomes in Adults with Healthy Skin
ConclusionThese data provide new evidence for the role of a novel multiple-active-ingredient formulation for improving skin outcomes up to 28 days following microneedling in adults with healthy skin when compared with a hyaluronic acid serum. The n-3 PUFA content of this formulation may drive accelerated inflammation resolution and wound healing alongside the complementary action of the other active ingredients, leading to the observed improvements in erythema, luminosity and skin texture. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - October 14, 2023 Category: Dermatology Source Type: research
Management of Pediatric Psoriasis: A U.S. Survey Based on Visits from the National Ambulatory Medical Care Survey (NAMCS)
ConclusionUse of off-label treatments was common for pediatric psoriasis. Most children with psoriasis were treated with topicals, of which tacrolimus, an unapproved treatment, was the most common. The frequent use of tacrolimus could indicate an avoidance of corticosteroids in children. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - October 13, 2023 Category: Dermatology Source Type: research
Treatments for Moderate-to-Severe Alopecia Areata: A Systematic Narrative Review
AbstractTreatments for alopecia areata (AA) have traditionally been prescribed off-label, and there has been no universal agreement on how to best manage the condition. Baricitinib is the first oral selective Janus kinase (JAK) inhibitor approved for the treatment of adults with severe AA. As a better understanding of the evidence supporting the management of AA in clinical practice is needed, we conducted a systematic literature review and subsequent narrative review to describe available evidence pertaining to the efficacy and tolerability of treatments currently recommended for adults with moderate-to-severe forms of AA...
Source: Dermatology and Therapy - October 13, 2023 Category: Dermatology Source Type: research
The Changing Tasks of Medicine and Dermatology in the Twenty-First Century: The Need for Improved Information Capture Tools and Processes
AbstractThe delivery of dermatology services has undergone dramatic changes in the past century. The goals and timelines of care have evolved as have the diagnostic and therapeutic tools, resulting in the need to capture and manage information differently, both qualitatively and quantitatively. The predominant and basic office-based ambulatory care model has remained relatively unchanged. Patients and providers interact with minimal pre-visit preparation using the “agenda-less” meeting model. This care model is ill-suited to manage the vastly expanded data capture and processing requirement of twenty-first century derm...
Source: Dermatology and Therapy - October 13, 2023 Category: Dermatology Source Type: research
Management of Pediatric Psoriasis: A U.S. Survey Based on Visits from the National Ambulatory Medical Care Survey (NAMCS)
ConclusionUse of off-label treatments was common for pediatric psoriasis. Most children with psoriasis were treated with topicals, of which tacrolimus, an unapproved treatment, was the most common. The frequent use of tacrolimus could indicate an avoidance of corticosteroids in children. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - October 13, 2023 Category: Dermatology Source Type: research
Treatments for Moderate-to-Severe Alopecia Areata: A Systematic Narrative Review
AbstractTreatments for alopecia areata (AA) have traditionally been prescribed off-label, and there has been no universal agreement on how to best manage the condition. Baricitinib is the first oral selective Janus kinase (JAK) inhibitor approved for the treatment of adults with severe AA. As a better understanding of the evidence supporting the management of AA in clinical practice is needed, we conducted a systematic literature review and subsequent narrative review to describe available evidence pertaining to the efficacy and tolerability of treatments currently recommended for adults with moderate-to-severe forms of AA...
Source: Dermatology and Therapy - October 13, 2023 Category: Dermatology Source Type: research
The Changing Tasks of Medicine and Dermatology in the Twenty-First Century: The Need for Improved Information Capture Tools and Processes
AbstractThe delivery of dermatology services has undergone dramatic changes in the past century. The goals and timelines of care have evolved as have the diagnostic and therapeutic tools, resulting in the need to capture and manage information differently, both qualitatively and quantitatively. The predominant and basic office-based ambulatory care model has remained relatively unchanged. Patients and providers interact with minimal pre-visit preparation using the “agenda-less” meeting model. This care model is ill-suited to manage the vastly expanded data capture and processing requirement of twenty-first century derm...
Source: Dermatology and Therapy - October 13, 2023 Category: Dermatology Source Type: research
