Virtual Learning Decreases the Carbon Footprint of Medical Education
ConclusionThe use of a virtual CME webinar led to a significant reduction in travel-related carbon dioxide emissions when compared to running the same program in-person event. When accounting for all passengers traveling via plane on any flight, driving to an event produced more emissions per participant than flying. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - March 26, 2024 Category: Dermatology Source Type: research
Inconsistent Associations Between Risk Factor Profiles and Adjuvant Radiation Therapy (ART) Treatment in Patients with Cutaneous Squamous Cell Carcinoma and Utility of the 40-Gene Expression Profile to Refine ART Guidance
ConclusionsART guidance is not determined by the presence of specific clinicopathologic factors, with treated and untreated patients sharing the same risk factor profiles. cSCC risk determination based on NCCN recommendations for clinical factor assessment results in inconsistent use of ART. Including tumor biology-based prognostic information from the 40-GEP refines risk and identifies patients who are most appropriate and likely to benefit from ART, and those that can consider deferring ART. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - March 23, 2024 Category: Dermatology Source Type: research
Comparing Achievement of National Psoriasis Foundation Treatment Targets among Patients with Plaque Psoriasis Treated with Ixekizumab versus Other Biologics in Clinical and Real-World Studies
ConclusionAcross both clinical studies and real-world settings, more patients treated with IXE achieved NPF target and acceptable responses at week 12 compared with those treated with other biologics.Trial RegistrationUNCOVER-2 (NCT01597245); UNCOVER-3 (NCT01646177); IXORA-R (NCT03573323); IXORA-S (NCT02561806); PSoHO (EUPAS24207). (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - March 23, 2024 Category: Dermatology Source Type: research
Inconsistent Associations Between Risk Factor Profiles and Adjuvant Radiation Therapy (ART) Treatment in Patients with Cutaneous Squamous Cell Carcinoma and Utility of the 40-Gene Expression Profile to Refine ART Guidance
ConclusionsART guidance is not determined by the presence of specific clinicopathologic factors, with treated and untreated patients sharing the same risk factor profiles. cSCC risk determination based on NCCN recommendations for clinical factor assessment results in inconsistent use of ART. Including tumor biology-based prognostic information from the 40-GEP refines risk and identifies patients who are most appropriate and likely to benefit from ART, and those that can consider deferring ART. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - March 23, 2024 Category: Dermatology Source Type: research
Comparing Achievement of National Psoriasis Foundation Treatment Targets among Patients with Plaque Psoriasis Treated with Ixekizumab versus Other Biologics in Clinical and Real-World Studies
ConclusionAcross both clinical studies and real-world settings, more patients treated with IXE achieved NPF target and acceptable responses at week 12 compared with those treated with other biologics.Trial RegistrationUNCOVER-2 (NCT01597245); UNCOVER-3 (NCT01646177); IXORA-R (NCT03573323); IXORA-S (NCT02561806); PSoHO (EUPAS24207). (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - March 23, 2024 Category: Dermatology Source Type: research
Characteristics and Management of Patients with Alopecia Areata and Selected Comorbid Conditions: Results from a Survey in Five European Countries
ConclusionThis analysis provided insights into the burden and management of AA in patients presenting with atopic, autoimmune, and psychiatric comorbid conditions in five European countries. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - March 21, 2024 Category: Dermatology Source Type: research
Management of Patients Affected by Moderate-to-Severe Atopic Dermatitis with JAK Inhibitors in Real-World Clinical Practice: An Italian Delphi Consensus
ConclusionGiven the wide use of JAKi in clinical practice, it is crucial to establish a specific follow-up for each patient ’s phenotype in order to achieve the best possible clinical outcome and minimize potential adverse events. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - March 21, 2024 Category: Dermatology Source Type: research
Characteristics and Management of Patients with Alopecia Areata and Selected Comorbid Conditions: Results from a Survey in Five European Countries
ConclusionThis analysis provided insights into the burden and management of AA in patients presenting with atopic, autoimmune, and psychiatric comorbid conditions in five European countries. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - March 21, 2024 Category: Dermatology Source Type: research
Management of Patients Affected by Moderate-to-Severe Atopic Dermatitis with JAK Inhibitors in Real-World Clinical Practice: An Italian Delphi Consensus
ConclusionGiven the wide use of JAKi in clinical practice, it is crucial to establish a specific follow-up for each patient ’s phenotype in order to achieve the best possible clinical outcome and minimize potential adverse events. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - March 21, 2024 Category: Dermatology Source Type: research
Effect of Makeup Use on Depressive Symptoms: An Open, Randomized and Controlled Trial
ConclusionThe results show that encouraging the frequent use of makeup, a practice that can be achieved by most people and which is simple and inexpensive to implement, can contribute to effective and sustainable improvement in the well-being and mental health of a significant portion of the population. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - March 21, 2024 Category: Dermatology Source Type: research
Development and Psychometric Validation of a Patient-Reported Outcome Measure to Assess the Signs and Symptoms of Chronic Hand Eczema: The Hand Eczema Symptom Diary (HESD)
ConclusionThe HESD is the first CHE-specific, patient-reported outcome measure of CHE signs/symptoms developed and validated in line with regulatory guidance. This article provides evidence of strong content validity and psychometric validity and shows improvements of ≥ 4 points on 7-day average HESD scores represent clinically meaningful, important changes.Trial RegistrationNCT03683719, NCT04871711. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - March 15, 2024 Category: Dermatology Source Type: research
Response Types and Factors Associated with Response Types to Biologic Therapies in Patients with Moderate-to-Severe Plaque Psoriasis from Two Randomized Clinical Trials
ConclusionsEarly treatment response and baseline characteristics, including smoking, psoriasis duration, and obesity, may be associated with longer-term response to biologics.Trial Registration NumbersECLIPSE: NCT03090100, VOYAGE 1: NCT02207231. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - March 15, 2024 Category: Dermatology Source Type: research
Development and Psychometric Validation of a Patient-Reported Outcome Measure to Assess the Signs and Symptoms of Chronic Hand Eczema: The Hand Eczema Symptom Diary (HESD)
ConclusionThe HESD is the first CHE-specific, patient-reported outcome measure of CHE signs/symptoms developed and validated in line with regulatory guidance. This article provides evidence of strong content validity and psychometric validity and shows improvements of ≥ 4 points on 7-day average HESD scores represent clinically meaningful, important changes.Trial RegistrationNCT03683719, NCT04871711. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - March 15, 2024 Category: Dermatology Source Type: research
Response Types and Factors Associated with Response Types to Biologic Therapies in Patients with Moderate-to-Severe Plaque Psoriasis from Two Randomized Clinical Trials
ConclusionsEarly treatment response and baseline characteristics, including smoking, psoriasis duration, and obesity, may be associated with longer-term response to biologics.Trial Registration NumbersECLIPSE: NCT03090100, VOYAGE 1: NCT02207231. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - March 15, 2024 Category: Dermatology Source Type: research
