Growth Hormone, Atherosclerosis and Peripheral Arterial Disease: Exploring the Spectrum from Acromegaly to Growth Hormone Deficiency
Curr Vasc Pharmacol. 2023 Nov 13. doi: 10.2174/0115701611269162231106042956. Online ahead of print.ABSTRACTGrowth hormone (GH) and insulin-like growth factor 1 (IGF-1) are increasingly recognised for their role in cardiovascular (CV) physiology. The GH-IGF-1 axis plays an essential role in the development of the CV system as well as in the complex molecular network that regulates cardiac and endothelial structure and function. A considerable correlation between GH levels and CV mortality exists even among individuals in the general population without a notable deviation in the GHIGF- 1 axis functioning. In addition, over t...
Source: Current Vascular Pharmacology - November 14, 2023 Category: Drugs & Pharmacology Authors: Herman R Janez A Mikhailidis Dp Poredos P Blinc A Sabovic M Bajuk Studen K Schernthaner Gh Anagnostis P Antignani Pl Jensterle M Source Type: research
Thyroid Disorders and Peripheral Arterial Disease
Curr Vasc Pharmacol. 2023 Nov 10. doi: 10.2174/0115701611271284231105063148. Online ahead of print.ABSTRACTHypothyroidism and hyperthyroidism, both overt and subclinical, are associated with increased risk of cardiovascular morbidity and mortality. The association between thyroid-stimulating hormone levels and cardiovascular risk has been demonstrated in large epidemiological studies and meta-analyses and is now considered a U-shaped curve. Several pathophysiological mechanisms linking thyroid and cardiovascular disease are known; however, specific clinical complications of peripheral arterial disease as endpoints of clini...
Source: Current Vascular Pharmacology - November 14, 2023 Category: Drugs & Pharmacology Authors: Katica Bajuk Studen Simona Gaberscek Katja Zaletel Ales Blinc Miso Sabovic Gerit-Holger Schernthaner Panagiotis Anagnostis Pier Luigi Antignani Mojca Jensterle Dimitri P Mikhailidis Pavel Poredos Source Type: research
Lanthanum Hydroxide and Chronic Kidney Disease Mineral and Bone Disorder: A Rat Model
CONCLUSION: LH can inhibit the occurrence and development of vascular calcification and bone abnormalities in AKI rats by inhibiting the NF-κB and RANKL/OPG signaling pathways.PMID:37961858 | DOI:10.2174/0115701611254269231105063028 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - November 14, 2023 Category: Drugs & Pharmacology Authors: Chao Gu Ting Zhang Yuan Gao Xiaojia Li Xiaorong Yuan Qiwen Wang Hong Liu Ruilan Han Gang Li Source Type: research
Growth Hormone, Atherosclerosis and Peripheral Arterial Disease: Exploring the Spectrum from Acromegaly to Growth Hormone Deficiency
Curr Vasc Pharmacol. 2023 Nov 13. doi: 10.2174/0115701611269162231106042956. Online ahead of print.ABSTRACTGrowth hormone (GH) and insulin-like growth factor 1 (IGF-1) are increasingly recognised for their role in cardiovascular (CV) physiology. The GH-IGF-1 axis plays an essential role in the development of the CV system as well as in the complex molecular network that regulates cardiac and endothelial structure and function. A considerable correlation between GH levels and CV mortality exists even among individuals in the general population without a notable deviation in the GHIGF- 1 axis functioning. In addition, over t...
Source: Current Vascular Pharmacology - November 14, 2023 Category: Drugs & Pharmacology Authors: Herman R Janez A Mikhailidis Dp Poredos P Blinc A Sabovic M Bajuk Studen K Schernthaner Gh Anagnostis P Antignani Pl Jensterle M Source Type: research
Thyroid Disorders and Peripheral Arterial Disease
Curr Vasc Pharmacol. 2023 Nov 10. doi: 10.2174/0115701611271284231105063148. Online ahead of print.ABSTRACTHypothyroidism and hyperthyroidism, both overt and subclinical, are associated with increased risk of cardiovascular morbidity and mortality. The association between thyroid-stimulating hormone levels and cardiovascular risk has been demonstrated in large epidemiological studies and meta-analyses and is now considered a U-shaped curve. Several pathophysiological mechanisms linking thyroid and cardiovascular disease are known; however, specific clinical complications of peripheral arterial disease as endpoints of clini...
Source: Current Vascular Pharmacology - November 14, 2023 Category: Drugs & Pharmacology Authors: Katica Bajuk Studen Simona Gaberscek Katja Zaletel Ales Blinc Miso Sabovic Gerit-Holger Schernthaner Panagiotis Anagnostis Pier Luigi Antignani Mojca Jensterle Dimitri P Mikhailidis Pavel Poredos Source Type: research
Lanthanum Hydroxide and Chronic Kidney Disease Mineral and Bone Disorder: A Rat Model
CONCLUSION: LH can inhibit the occurrence and development of vascular calcification and bone abnormalities in AKI rats by inhibiting the NF-κB and RANKL/OPG signaling pathways.PMID:37961858 | DOI:10.2174/0115701611254269231105063028 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - November 14, 2023 Category: Drugs & Pharmacology Authors: Chao Gu Ting Zhang Yuan Gao Xiaojia Li Xiaorong Yuan Qiwen Wang Hong Liu Ruilan Han Gang Li Source Type: research
Growth Hormone, Atherosclerosis and Peripheral Arterial Disease: Exploring the Spectrum from Acromegaly to Growth Hormone Deficiency
Curr Vasc Pharmacol. 2023 Nov 13. doi: 10.2174/0115701611269162231106042956. Online ahead of print.ABSTRACTGrowth hormone (GH) and insulin-like growth factor 1 (IGF-1) are increasingly recognised for their role in cardiovascular (CV) physiology. The GH-IGF-1 axis plays an essential role in the development of the CV system as well as in the complex molecular network that regulates cardiac and endothelial structure and function. A considerable correlation between GH levels and CV mortality exists even among individuals in the general population without a notable deviation in the GHIGF- 1 axis functioning. In addition, over t...
Source: Current Vascular Pharmacology - November 14, 2023 Category: Drugs & Pharmacology Authors: Herman R Janez A Mikhailidis Dp Poredos P Blinc A Sabovic M Bajuk Studen K Schernthaner Gh Anagnostis P Antignani Pl Jensterle M Source Type: research
The Fundamental Role of Medical Treatment in the Prevention of CarotidRelated Strokes: Insights from a Multispecialty Consensus Document
Curr Vasc Pharmacol. 2023 Nov 1. doi: 10.2174/0115701611282696231101072656. Online ahead of print.NO ABSTRACTPMID:37909660 | DOI:10.2174/0115701611282696231101072656 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - November 1, 2023 Category: Drugs & Pharmacology Authors: Kosmas I Paraskevas Piotr Musialek Dimitri P Mikhailidis Gregory Y H Lip Source Type: research
The Fundamental Role of Medical Treatment in the Prevention of CarotidRelated Strokes: Insights from a Multispecialty Consensus Document
Curr Vasc Pharmacol. 2023 Nov 1. doi: 10.2174/0115701611282696231101072656. Online ahead of print.NO ABSTRACTPMID:37909660 | DOI:10.2174/0115701611282696231101072656 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - November 1, 2023 Category: Drugs & Pharmacology Authors: Kosmas I Paraskevas Piotr Musialek Dimitri P Mikhailidis Gregory Y H Lip Source Type: research
The Fundamental Role of Medical Treatment in the Prevention of CarotidRelated Strokes: Insights from a Multispecialty Consensus Document
Curr Vasc Pharmacol. 2023 Nov 1. doi: 10.2174/0115701611282696231101072656. Online ahead of print.NO ABSTRACTPMID:37909660 | DOI:10.2174/0115701611282696231101072656 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - November 1, 2023 Category: Drugs & Pharmacology Authors: Kosmas I Paraskevas Piotr Musialek Dimitri P Mikhailidis Gregory Y H Lip Source Type: research
The Fundamental Role of Medical Treatment in the Prevention of CarotidRelated Strokes: Insights from a Multispecialty Consensus Document
Curr Vasc Pharmacol. 2023 Nov 1. doi: 10.2174/0115701611282696231101072656. Online ahead of print.NO ABSTRACTPMID:37909660 | DOI:10.2174/0115701611282696231101072656 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - November 1, 2023 Category: Drugs & Pharmacology Authors: Kosmas I Paraskevas Piotr Musialek Dimitri P Mikhailidis Gregory Y H Lip Source Type: research
The Fundamental Role of Medical Treatment in the Prevention of CarotidRelated Strokes: Insights from a Multispecialty Consensus Document
Curr Vasc Pharmacol. 2023 Nov 1. doi: 10.2174/0115701611282696231101072656. Online ahead of print.NO ABSTRACTPMID:37909660 | DOI:10.2174/0115701611282696231101072656 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - November 1, 2023 Category: Drugs & Pharmacology Authors: Kosmas I Paraskevas Piotr Musialek Dimitri P Mikhailidis Gregory Y H Lip Source Type: research
The Fundamental Role of Medical Treatment in the Prevention of CarotidRelated Strokes: Insights from a Multispecialty Consensus Document
Curr Vasc Pharmacol. 2023 Nov 1. doi: 10.2174/0115701611282696231101072656. Online ahead of print.NO ABSTRACTPMID:37909660 | DOI:10.2174/0115701611282696231101072656 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - November 1, 2023 Category: Drugs & Pharmacology Authors: Kosmas I Paraskevas Piotr Musialek Dimitri P Mikhailidis Gregory Y H Lip Source Type: research
The Fundamental Role of Medical Treatment in the Prevention of CarotidRelated Strokes: Insights from a Multispecialty Consensus Document
Curr Vasc Pharmacol. 2023 Nov 1. doi: 10.2174/0115701611282696231101072656. Online ahead of print.NO ABSTRACTPMID:37909660 | DOI:10.2174/0115701611282696231101072656 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - November 1, 2023 Category: Drugs & Pharmacology Authors: Kosmas I Paraskevas Piotr Musialek Dimitri P Mikhailidis Gregory Y H Lip Source Type: research
The Fundamental Role of Medical Treatment in the Prevention of CarotidRelated Strokes: Insights from a Multispecialty Consensus Document
Curr Vasc Pharmacol. 2023 Nov 1. doi: 10.2174/0115701611282696231101072656. Online ahead of print.NO ABSTRACTPMID:37909660 | DOI:10.2174/0115701611282696231101072656 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - November 1, 2023 Category: Drugs & Pharmacology Authors: Kosmas I Paraskevas Piotr Musialek Dimitri P Mikhailidis Gregory Y H Lip Source Type: research
