Diagnostic Value of Serum Galectin-3 Binding Protein Level in Patients with Pulmonary Arterial Hypertension
CONCLUSION: Serum Gal-3BP levels were increased in patients with PAH, and levels of Gal-3BP were associated with the severity of PAH. Gal-3BP might have predictive value for the diagnosis and prognosis of PAH.PMID:38038005 | DOI:10.2174/0115701611268078231010072521 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - December 1, 2023 Category: Drugs & Pharmacology Authors: Mingfei Li Wenzhi Pan Dan Tian Dandan Chen Xiaochun Zhang Yuan Zhang Shasha Chen Daxin Zhou Junbo Ge Source Type: research
Endocrine Disorders and Peripheral Arterial Disease - A Series of Reviews Cushing Syndrome-Cortisol Excess
In conclusion, CS promotes atherosclerosis, including peripheral artery disease, by causing functional and morphological deterioration of the arterial vessel wall and increasing the presence of classical risk factors of atherosclerosis.PMID:38038006 | DOI:10.2174/0115701611272145231106053914 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - December 1, 2023 Category: Drugs & Pharmacology Authors: P Poredos G H Schernthaner A Blinc D P Mikhailidis M Jensterle P Anagnostis P L Antignani K Bajuk Studen M Šabović M K Je žovnik Source Type: research
Benefits of Statins and Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK-9) Inhibitors for Patients with Peripheral Arterial Disease
Curr Vasc Pharmacol. 2023 Nov 30. doi: 10.2174/0115701611292747231129080204. Online ahead of print.NO ABSTRACTPMID:38037835 | DOI:10.2174/0115701611292747231129080204 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - December 1, 2023 Category: Drugs & Pharmacology Authors: Kosmas I Paraskevas Debabrata Mukherjee Theofanis T Papas Source Type: research
Study of Osteopontin as a Marker of Arteriovenous Shunt Stenosis in Hemodialysis Patients
CONCLUSION: OPN levels in HD patients may be useful markers for predicting and detecting AVF stenosis.PMID:38038003 | DOI:10.2174/0115701611260120231106081701 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - December 1, 2023 Category: Drugs & Pharmacology Authors: Marwa R Elbarbary Laila A Ahmed Doaa A El-Adl Alshimaa A Ezzat Sherif A Nassib Source Type: research
Evaluation of Clinical, Echocardiographic, and Therapeutic Characteristics, and Prognostic Outcomes of Coexisting Heart Failure among Patients with Atrial Fibrillation: The Jordan Atrial Fibrillation (JoFib) Study
CONCLUSION: Coexisting AF+HF was associated with a more labile and higher-risk population among Jordanian patients. Furthermore, coexisting HF independently predicted higher all-cause mortality and cardiovascular mortality. Efforts should be made to efficiently identify such cases early and treat them aggressively.PMID:38038004 | DOI:10.2174/0115701611260211231115094716 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - December 1, 2023 Category: Drugs & Pharmacology Authors: Nasr Alrabadi Mohammed Al-Nusair Farah K El-Zubi Mais Tashtoush Osama Alzoubi Sa'ed Khamis Majd M Masadeh Karem H Alzoubi Mohammed Al-Hiari Ayman Hammoudeh Source Type: research
Diagnostic Value of Serum Galectin-3 Binding Protein Level in Patients with Pulmonary Arterial Hypertension
CONCLUSION: Serum Gal-3BP levels were increased in patients with PAH, and levels of Gal-3BP were associated with the severity of PAH. Gal-3BP might have predictive value for the diagnosis and prognosis of PAH.PMID:38038005 | DOI:10.2174/0115701611268078231010072521 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - December 1, 2023 Category: Drugs & Pharmacology Authors: Mingfei Li Wenzhi Pan Dan Tian Dandan Chen Xiaochun Zhang Yuan Zhang Shasha Chen Daxin Zhou Junbo Ge Source Type: research
Endocrine Disorders and Peripheral Arterial Disease - A Series of Reviews Cushing Syndrome-Cortisol Excess
In conclusion, CS promotes atherosclerosis, including peripheral artery disease, by causing functional and morphological deterioration of the arterial vessel wall and increasing the presence of classical risk factors of atherosclerosis.PMID:38038006 | DOI:10.2174/0115701611272145231106053914 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - December 1, 2023 Category: Drugs & Pharmacology Authors: Poredos P Schernthaner Gh Blinc A Mikhailidis Dp Jensterle M Anagnostis P Antignani Pl Bajuk Studen K Šabović M Je žovnik Mk Source Type: research
Beta-blockers in Hypertensive Left Ventricular Hypertrophy and Atrial Fibrillation Prevention
CONCLUSION: BBs are recommended (as a class) for AF prevention in several contemporary guidelines for HTN. LVH regression in HTN - used as a single criterion for the choice of antihypertensive medication - does not capture this protective effect. Consequently, it is worth studying how meaningful this antiarrhythmic action (to prevent AF) of BBs is in patients with HTN LVH in addition to a RAAS blocker.PMID:38031765 | DOI:10.2174/0115701611264647231110101700 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - November 30, 2023 Category: Drugs & Pharmacology Authors: Goran Koracevic Sladjana Micic Milovan Stojanovic Marija Zdravkovic Dragan Simic Tomislav Kostic Vesna Atanaskovic Ruzica Tomasevic Jankovic Source Type: research
The Role of TRIM Proteins in Vascular Disease
Curr Vasc Pharmacol. 2023 Nov 22. doi: 10.2174/0115701611241848231114111618. Online ahead of print.ABSTRACTThere are more than 80 different tripartite motifs (TRIM) proteins within the E3 ubiquitin ligase subfamily, including proteins that regulate intracellular signaling, apoptosis, autophagy, proliferation, inflammation, and immunity through the ubiquitination of target proteins. Studies conducted in recent years have unraveled the importance of TRIM proteins in the pathophysiology of vascular diseases. In this review, we describe the effects of TRIM proteins on vascular endothelial cells, smooth muscle cells, heart, and...
Source: Current Vascular Pharmacology - November 30, 2023 Category: Drugs & Pharmacology Authors: Xinxin Chen Xiaolong Chen Source Type: research
Beta-blockers in Hypertensive Left Ventricular Hypertrophy and Atrial Fibrillation Prevention
CONCLUSION: BBs are recommended (as a class) for AF prevention in several contemporary guidelines for HTN. LVH regression in HTN - used as a single criterion for the choice of antihypertensive medication - does not capture this protective effect. Consequently, it is worth studying how meaningful this antiarrhythmic action (to prevent AF) of BBs is in patients with HTN LVH in addition to a RAAS blocker.PMID:38031765 | DOI:10.2174/0115701611264647231110101700 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - November 30, 2023 Category: Drugs & Pharmacology Authors: Goran Koracevic Sladjana Micic Milovan Stojanovic Marija Zdravkovic Dragan Simic Tomislav Kostic Vesna Atanaskovic Ruzica Tomasevic Jankovic Source Type: research
The Role of TRIM Proteins in Vascular Disease
Curr Vasc Pharmacol. 2023 Nov 22. doi: 10.2174/0115701611241848231114111618. Online ahead of print.ABSTRACTThere are more than 80 different tripartite motifs (TRIM) proteins within the E3 ubiquitin ligase subfamily, including proteins that regulate intracellular signaling, apoptosis, autophagy, proliferation, inflammation, and immunity through the ubiquitination of target proteins. Studies conducted in recent years have unraveled the importance of TRIM proteins in the pathophysiology of vascular diseases. In this review, we describe the effects of TRIM proteins on vascular endothelial cells, smooth muscle cells, heart, and...
Source: Current Vascular Pharmacology - November 30, 2023 Category: Drugs & Pharmacology Authors: Xinxin Chen Xiaolong Chen Source Type: research
P2Y12 Inhibitor or Aspirin Monotherapy in Patients with Coronary Artery Disease: is it Time for a Paradigm Shift?
Curr Vasc Pharmacol. 2023 Nov 23. doi: 10.2174/0115701611269735231106110250. Online ahead of print.NO ABSTRACTPMID:38018206 | DOI:10.2174/0115701611269735231106110250 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - November 29, 2023 Category: Drugs & Pharmacology Authors: Felice Gragnano Antonio Capolongo Paolo Calabr ò Source Type: research
Thyroid Disorders and Peripheral Arterial Disease
Curr Vasc Pharmacol. 2023 Nov 10. doi: 10.2174/0115701611271284231105063148. Online ahead of print.ABSTRACTHypothyroidism and hyperthyroidism, both overt and subclinical, are associated with increased risk of cardiovascular morbidity and mortality. The association between thyroid-stimulating hormone levels and cardiovascular risk has been demonstrated in large epidemiological studies and meta-analyses and is now considered a U-shaped curve. Several pathophysiological mechanisms linking thyroid and cardiovascular disease are known; however, specific clinical complications of peripheral arterial disease as endpoints of clini...
Source: Current Vascular Pharmacology - November 14, 2023 Category: Drugs & Pharmacology Authors: Katica Bajuk Studen Simona Gaberscek Katja Zaletel Ales Blinc Miso Sabovic Gerit-Holger Schernthaner Panagiotis Anagnostis Pier Luigi Antignani Mojca Jensterle Dimitri P Mikhailidis Pavel Poredos Source Type: research
Lanthanum Hydroxide and Chronic Kidney Disease Mineral and Bone Disorder: A Rat Model
CONCLUSION: LH can inhibit the occurrence and development of vascular calcification and bone abnormalities in AKI rats by inhibiting the NF-κB and RANKL/OPG signaling pathways.PMID:37961858 | DOI:10.2174/0115701611254269231105063028 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - November 14, 2023 Category: Drugs & Pharmacology Authors: Chao Gu Ting Zhang Yuan Gao Xiaojia Li Xiaorong Yuan Qiwen Wang Hong Liu Ruilan Han Gang Li Source Type: research
Growth Hormone, Atherosclerosis and Peripheral Arterial Disease: Exploring the Spectrum from Acromegaly to Growth Hormone Deficiency
Curr Vasc Pharmacol. 2023 Nov 13. doi: 10.2174/0115701611269162231106042956. Online ahead of print.ABSTRACTGrowth hormone (GH) and insulin-like growth factor 1 (IGF-1) are increasingly recognised for their role in cardiovascular (CV) physiology. The GH-IGF-1 axis plays an essential role in the development of the CV system as well as in the complex molecular network that regulates cardiac and endothelial structure and function. A considerable correlation between GH levels and CV mortality exists even among individuals in the general population without a notable deviation in the GHIGF- 1 axis functioning. In addition, over t...
Source: Current Vascular Pharmacology - November 14, 2023 Category: Drugs & Pharmacology Authors: Herman R Janez A Mikhailidis Dp Poredos P Blinc A Sabovic M Bajuk Studen K Schernthaner Gh Anagnostis P Antignani Pl Jensterle M Source Type: research
