Current Drug Discovery Technologies This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The Nanotech Potential of Curcumin in Pharmaceuticals: An Overview
Curr Drug Discov Technol. 2023 Jul 26. doi: 10.2174/1570163820666230726125809. Online ahead of print.ABSTRACTIt is safe to use Curcumin as a cosmetic and therapeutic ingredient in pharmaceutical products. For the uses mentioned above and for fundamental research, it is essential to obtain pure Curcumin from plant sources. There is a requirement for effective extraction and purification techniques that adhere to green chemistry standards for efficiency improvement, process safety, and environmental friendliness. Several outstanding studies have looked into the extraction and purification of Curcumin. This review thoroughly ...
Source: Current Drug Discovery Technologies - July 26, 2023 Category: Drugs & Pharmacology Authors: Sagar Pardeshi Popat Mohite Tanavirsing Rajput Abhijeet Puri Source Type: research

CBD: A Potential Lead against Hair Loss, Alopecia, and its Potential Mechanisms
CONCLUSION: The data obtained from the literature regarding CBD and hair loss provide a scientific basis for CBD use in alopecia. Additionally, a more precise and comprehensive study concerning CBD needs to be carried out at the pre-clinical and clinical levels.PMID:37475557 | DOI:10.2174/1570163820666230720153607 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - July 21, 2023 Category: Drugs & Pharmacology Authors: Pranay Wal Ankita Wal Source Type: research

Docking, Synthesis, and Evaluation of 4-hydroxy-1-phenyl-2(1H)-quinolone Derivatives as Anticancer Agents
CONCLUSION: Compound IVg showed the highest MolDock score and was also found to be most potent against both the cell line, A549, and MDA-MB.PMID:37469155 | DOI:10.2174/1570163820666230719110932 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - July 20, 2023 Category: Drugs & Pharmacology Authors: Chaitali Prabhu Tendulkar Prachita Gauns Dessai Shivlingrao MamleDesai Amrita Kadam Source Type: research

The Biogenetic Synthesis of Metallic Nanoparticles and the Role They Play in Anti-inflammatory Drug Treatment
CONCLUSION: The current research focuses on metallic nanoparticles employed as anti-inflammatory medication molecules, although nanoparticles have applications in various areas (medicine, chemical engineering, and agriculture). Nanoparticles have a large surface-to-volume ratio, which can help them to penetrate cell membranes, and because of their solid ligand-binding capabilities, nanoparticles have been used in the medical treatment of inflammatory pathologies.PMID:37464822 | DOI:10.2174/1570163820666230718123544 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - July 19, 2023 Category: Drugs & Pharmacology Authors: Meena Kurup Mohan Kumar Sambathkumar Ramanathan Margnat Chandra Source Type: research

Acute Oral Toxicity, Antioxidant Activity, and Molecular Docking Study of 2-(4-Bromo-phenoxy)-N-[6-chloro-4-(4-chlorophenyl)-3-cyano-4H-chromen-2-yl]-acetamide
CONCLUSION: This compound can be exploited as a lead molecule in further research.PMID:37464823 | DOI:10.2174/1570163820666230718145955 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - July 19, 2023 Category: Drugs & Pharmacology Authors: Divya Chauhan Anurag Agrawal Jagdish K Sahu Sushil Kumar Source Type: research

In-vitro Evaluation of Triazine Scaffold for Anticancer Drug Development: A Review
CONCLUSION: The content of the review would be helpful to update the researchers working towards the synthesis and designing of new molecules for the treatment of various types of cancer disease with the recent molecules that have been produced from the triazine scaffold. Triazine scaffolds based on 1,3,5-triazine considerably boost molecular diversity levels and enable covering chemical space in key medicinal chemistry fields.PMID:37461340 | DOI:10.2174/1570163820666230717161610 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - July 18, 2023 Category: Drugs & Pharmacology Authors: Pragya Dubey Dharam Pal Pathak Faraat Ali Garima Chauhan Vivekanandan Kalaiselvan Source Type: research

Investigating the effects and side effects of two antipsychotic drugs in the treatment of children and adolescents with Tourette syndrome: a semi-experimental research
CONCLUSION: According to the results, the two medicines, Aripiprazole and Risperidone, effectively improved the symptoms of Tourette's disorder and its overall severity. However, there were no significant statistical differences between them. Furthermore, in terms of the medical side effects, the statistical comparison between the two medicines was impossible due to the small number of complications.PMID:37303178 | DOI:10.2174/1570163820666230609095720 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - June 12, 2023 Category: Drugs & Pharmacology Authors: Atefeh Soltanifar Raheleh Lashkarnevis Maliheh Ziaee Fatemeh Moharari Roya Samadi Azadeh Soltanifar Maedeh Kamrani Source Type: research