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An Eco-friendly Strategy for the Synthesis of Spiro-benzimidazoquinazolinone and Spiro-benzothiazoloquinazolinone Derivatives using β-cyclodextrin as a Supramolecular Catalyst
CONCLUSION: The catalyst demonstrated remarkable effectiveness in producing the target compounds and conducting the reaction with different initial substances, resulting in excellent yields of the products, thereby confirming the broad applicability and versatility of this method.PMID:38151832 | DOI:10.2174/0115701638276530231220080041 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Jyoti Baranwal Swastika Singh Smriti Kushwaha Archana Jyoti Source Type: research

Biological Activities of Zinc Oxide Nanoparticles Green Synthesized Using the Aqueous Extract of Dracocephalum kotschyi Boiss
CONCLUSION: The noteworthy point is that the inhibitory rate of synthesized zinc oxide nanoparticles is higher compared to broad-spectrum antibiotics, such as chloramphenicol (MIC values 15 mg/ml). Determining the therapeutic and toxic dose of this product for humans requires further investigation and clinical trials.PMID:38151833 | DOI:10.2174/0115701638284118231220074251 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Foroogh Mirzania Iraj Salimikia Javad Ghasemian Yadegari Abdolrazagh Marzban Amirmasoud Firouzi Alireza Nazarzadeh Javid Aalaei Source Type: research

Design, Synthesis, Characterisation, and Evaluation of Substituted Quinolin-2-one Derivatives as Possible Anti-lung Cancer Agents
CONCLUSION: Compound VII a showed the highest MolDock score and was most potent against human lung cancer cell line Hop-62.PMID:38151847 | DOI:10.2174/0115701638258479231220051227 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Riya Swar Prachita Gauns Dessai Shivalingrao MamleDesai Sachin Chandavarkar Soniya Phadte B Biradar Source Type: research

An Eco-friendly Strategy for the Synthesis of Spiro-benzimidazoquinazolinone and Spiro-benzothiazoloquinazolinone Derivatives using β-cyclodextrin as a Supramolecular Catalyst
CONCLUSION: The catalyst demonstrated remarkable effectiveness in producing the target compounds and conducting the reaction with different initial substances, resulting in excellent yields of the products, thereby confirming the broad applicability and versatility of this method.PMID:38151832 | DOI:10.2174/0115701638276530231220080041 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Jyoti Baranwal Swastika Singh Smriti Kushwaha Archana Jyoti Source Type: research

Biological Activities of Zinc Oxide Nanoparticles Green Synthesized Using the Aqueous Extract of Dracocephalum kotschyi Boiss
CONCLUSION: The noteworthy point is that the inhibitory rate of synthesized zinc oxide nanoparticles is higher compared to broad-spectrum antibiotics, such as chloramphenicol (MIC values 15 mg/ml). Determining the therapeutic and toxic dose of this product for humans requires further investigation and clinical trials.PMID:38151833 | DOI:10.2174/0115701638284118231220074251 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Foroogh Mirzania Iraj Salimikia Javad Ghasemian Yadegari Abdolrazagh Marzban Amirmasoud Firouzi Alireza Nazarzadeh Javid Aalaei Source Type: research

Design, Synthesis, Characterisation, and Evaluation of Substituted Quinolin-2-one Derivatives as Possible Anti-lung Cancer Agents
CONCLUSION: Compound VII a showed the highest MolDock score and was most potent against human lung cancer cell line Hop-62.PMID:38151847 | DOI:10.2174/0115701638258479231220051227 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Riya Swar Prachita Gauns Dessai Shivalingrao MamleDesai Sachin Chandavarkar Soniya Phadte B Biradar Source Type: research

An Eco-friendly Strategy for the Synthesis of Spiro-benzimidazoquinazolinone and Spiro-benzothiazoloquinazolinone Derivatives using β-cyclodextrin as a Supramolecular Catalyst
CONCLUSION: The catalyst demonstrated remarkable effectiveness in producing the target compounds and conducting the reaction with different initial substances, resulting in excellent yields of the products, thereby confirming the broad applicability and versatility of this method.PMID:38151832 | DOI:10.2174/0115701638276530231220080041 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Jyoti Baranwal Swastika Singh Smriti Kushwaha Archana Jyoti Source Type: research

Biological Activities of Zinc Oxide Nanoparticles Green Synthesized Using the Aqueous Extract of Dracocephalum kotschyi Boiss
CONCLUSION: The noteworthy point is that the inhibitory rate of synthesized zinc oxide nanoparticles is higher compared to broad-spectrum antibiotics, such as chloramphenicol (MIC values 15 mg/ml). Determining the therapeutic and toxic dose of this product for humans requires further investigation and clinical trials.PMID:38151833 | DOI:10.2174/0115701638284118231220074251 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Foroogh Mirzania Iraj Salimikia Javad Ghasemian Yadegari Abdolrazagh Marzban Amirmasoud Firouzi Alireza Nazarzadeh Javid Aalaei Source Type: research

Design, Synthesis, Characterisation, and Evaluation of Substituted Quinolin-2-one Derivatives as Possible Anti-lung Cancer Agents
CONCLUSION: Compound VII a showed the highest MolDock score and was most potent against human lung cancer cell line Hop-62.PMID:38151847 | DOI:10.2174/0115701638258479231220051227 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Riya Swar Prachita Gauns Dessai Shivalingrao MamleDesai Sachin Chandavarkar Soniya Phadte B Biradar Source Type: research

An Eco-friendly Strategy for the Synthesis of Spiro-benzimidazoquinazolinone and Spiro-benzothiazoloquinazolinone Derivatives using β-cyclodextrin as a Supramolecular Catalyst
CONCLUSION: The catalyst demonstrated remarkable effectiveness in producing the target compounds and conducting the reaction with different initial substances, resulting in excellent yields of the products, thereby confirming the broad applicability and versatility of this method.PMID:38151832 | DOI:10.2174/0115701638276530231220080041 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Jyoti Baranwal Swastika Singh Smriti Kushwaha Archana Jyoti Source Type: research

Biological Activities of Zinc Oxide Nanoparticles Green Synthesized Using the Aqueous Extract of Dracocephalum kotschyi Boiss
CONCLUSION: The noteworthy point is that the inhibitory rate of synthesized zinc oxide nanoparticles is higher compared to broad-spectrum antibiotics, such as chloramphenicol (MIC values 15 mg/ml). Determining the therapeutic and toxic dose of this product for humans requires further investigation and clinical trials.PMID:38151833 | DOI:10.2174/0115701638284118231220074251 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Foroogh Mirzania Iraj Salimikia Javad Ghasemian Yadegari Abdolrazagh Marzban Amirmasoud Firouzi Alireza Nazarzadeh Javid Aalaei Source Type: research

Design, Synthesis, Characterisation, and Evaluation of Substituted Quinolin-2-one Derivatives as Possible Anti-lung Cancer Agents
CONCLUSION: Compound VII a showed the highest MolDock score and was most potent against human lung cancer cell line Hop-62.PMID:38151847 | DOI:10.2174/0115701638258479231220051227 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Riya Swar Prachita Gauns Dessai Shivalingrao MamleDesai Sachin Chandavarkar Soniya Phadte B Biradar Source Type: research

An Eco-friendly Strategy for the Synthesis of Spiro-benzimidazoquinazolinone and Spiro-benzothiazoloquinazolinone Derivatives using β-cyclodextrin as a Supramolecular Catalyst
CONCLUSION: The catalyst demonstrated remarkable effectiveness in producing the target compounds and conducting the reaction with different initial substances, resulting in excellent yields of the products, thereby confirming the broad applicability and versatility of this method.PMID:38151832 | DOI:10.2174/0115701638276530231220080041 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Jyoti Baranwal Swastika Singh Smriti Kushwaha Archana Jyoti Source Type: research

Biological Activities of Zinc Oxide Nanoparticles Green Synthesized Using the Aqueous Extract of Dracocephalum kotschyi Boiss
CONCLUSION: The noteworthy point is that the inhibitory rate of synthesized zinc oxide nanoparticles is higher compared to broad-spectrum antibiotics, such as chloramphenicol (MIC values 15 mg/ml). Determining the therapeutic and toxic dose of this product for humans requires further investigation and clinical trials.PMID:38151833 | DOI:10.2174/0115701638284118231220074251 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Foroogh Mirzania Iraj Salimikia Javad Ghasemian Yadegari Abdolrazagh Marzban Amirmasoud Firouzi Alireza Nazarzadeh Javid Aalaei Source Type: research

Design, Synthesis, Characterisation, and Evaluation of Substituted Quinolin-2-one Derivatives as Possible Anti-lung Cancer Agents
CONCLUSION: Compound VII a showed the highest MolDock score and was most potent against human lung cancer cell line Hop-62.PMID:38151847 | DOI:10.2174/0115701638258479231220051227 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Riya Swar Prachita Gauns Dessai Shivalingrao MamleDesai Sachin Chandavarkar Soniya Phadte B Biradar Source Type: research