Current Landscape of Various Techniques and Methods of Gene Therapy through CRISPR Cas9 along with its Pharmacological and Interventional Therapies in the Treatment of Type 2 Diabetes Mellitus
CONCLUSION: It can be concluded from the study that recent advancements in gene-editing technologies, such as CRISPR Cas9, have opened new avenues for the development of novel therapeutic approaches for T2DM. CRISPR Cas9 is a powerful tool that enables precise and targeted modifications of the genome.PMID:37867274 | DOI:10.2174/0115733998263079231011073803 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - October 23, 2023 Category: Endocrinology Authors: Pranay Wal Namra Aziz Harshit Prajapati Shashank Soni Ankita Wal Source Type: research
The Functional Role of microRNAs and mRNAs in Diabetic Kidney Disease: A Review
Curr Diabetes Rev. 2023 Oct 20. doi: 10.2174/0115733998270983231009094216. Online ahead of print.ABSTRACTDiabetes is a group of diseases marked by poor control of blood glucose levels. Diabetes mellitus (DM) occurs when pancreatic cells fail to make insulin, which is required to keep blood glucose levels stable, disorders, and so on. High glucose levels in the blood induce diabetic effects, which can cause catastrophic damage to bodily organs such as the eyes and lower extremities. Diabetes is classified into many forms, one of which is controlled by hyperglycemia or Diabetic Kidney Disease (DKD), and another that is not c...
Source: Current Diabetes Reviews - October 23, 2023 Category: Endocrinology Authors: Bhuvnesh Rai Jyotika Srivastava Pragati Saxena Source Type: research
Burden and Coping Strategies of Hypoglycemia in People with Diabetes
Curr Diabetes Rev. 2023 Oct 20. doi: 10.2174/0115733998271244231010100747. Online ahead of print.ABSTRACTHypoglycemia is a limiting adverse effect of glucose-lowering medications and particularly insulin replacement therapy. This review provides insights into the burden of hypoglycemia in the management of diabetes and outlines strategies available to reduce the risk of hypoglycemia and improve patients' well-being. People with type 1 diabetes are primarily affected by hypoglycemic episodes which are associated with direct physical harms like injuries and cardiac events as well as indirect psychosocial consequences includi...
Source: Current Diabetes Reviews - October 23, 2023 Category: Endocrinology Authors: Aris Liakos Thomas Karagiannis Ioannis Avgerinos Apostolos Tsapas Eleni Bekiari Source Type: research
Current Vaccination Practice in Diabetic (Diabetes I) Patients
Curr Diabetes Rev. 2023 Oct 6. doi: 10.2174/0115733998260361230927002739. Online ahead of print.ABSTRACTThe worldwide prevalence of diabetes, an endocrine condition, is rising quickly. The alarming rise of diabetes in recent years has emerged as a major contributor to premature death and illness among persons of working age. The potential use of immunomodulatory drugs to prevent diabetes has been a source of worry in light of recent advances in our understanding of the role of autoimmune responses in the development of diabetes. Vaccines can work in a variety of ways, including by eliminating autoreactive T-cells or by blo...
Source: Current Diabetes Reviews - October 20, 2023 Category: Endocrinology Authors: Yati Kumar Sonali Sundaram Deepika Yadav Source Type: research
Effect of the Theory-driven Educational Intervention on Self-Care Behavior and Glycosylated Hemoglobin Level in Patients with Type 2 Diabetes
CONCLUSION: Education based on the TPB was effective in improving the patients' self-care behavior and HbA1c index. Therefore, we suggest all medical centers to use the TPB as an effective and low-cost educational approach to improve diabetics' self-care behavior and health.PMID:37859319 | DOI:10.2174/0115733998253954230925050754 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - October 20, 2023 Category: Endocrinology Authors: Mojgan Pourmohammad Mina Maheri Hamid-Reza Khalkhali Fatemeh Moghaddam-Tabrizi Alireza Didarloo Source Type: research
From Gut to Glucose: A Comprehensive Review on Functional Foods and Dietary Interventions for Diabetes Management
CONCLUSION: This study has presented an exhaustive overview of dietary therapies and functional foods that have undergone extensive research to explore their potential advantages in the management of diabetes. It looks into the role of gut health in glucose regulation, discusses the impact of different dietary elements on the course of diabetes, and evaluates how well functional foods can help with glycemic control. Furthermore, it investigates the mechanistic aspects of these therapies, including their influence on insulin sensitivity, β-cell activity, and inflammation. It deliberates on the limitations and potential pro...
Source: Current Diabetes Reviews - October 20, 2023 Category: Endocrinology Authors: Nirali Patel Susha Dinesh Sameer Sharma Source Type: research
Current Vaccination Practice in Diabetic (Diabetes I) Patients
Curr Diabetes Rev. 2023 Oct 6. doi: 10.2174/0115733998260361230927002739. Online ahead of print.ABSTRACTThe worldwide prevalence of diabetes, an endocrine condition, is rising quickly. The alarming rise of diabetes in recent years has emerged as a major contributor to premature death and illness among persons of working age. The potential use of immunomodulatory drugs to prevent diabetes has been a source of worry in light of recent advances in our understanding of the role of autoimmune responses in the development of diabetes. Vaccines can work in a variety of ways, including by eliminating autoreactive T-cells or by blo...
Source: Current Diabetes Reviews - October 20, 2023 Category: Endocrinology Authors: Yati Kumar Sonali Sundaram Deepika Yadav Source Type: research
Effect of the Theory-driven Educational Intervention on Self-Care Behavior and Glycosylated Hemoglobin Level in Patients with Type 2 Diabetes
CONCLUSION: Education based on the TPB was effective in improving the patients' self-care behavior and HbA1c index. Therefore, we suggest all medical centers to use the TPB as an effective and low-cost educational approach to improve diabetics' self-care behavior and health.PMID:37859319 | DOI:10.2174/0115733998253954230925050754 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - October 20, 2023 Category: Endocrinology Authors: Mojgan Pourmohammad Mina Maheri Hamid-Reza Khalkhali Fatemeh Moghaddam-Tabrizi Alireza Didarloo Source Type: research
From Gut to Glucose: A Comprehensive Review on Functional Foods and Dietary Interventions for Diabetes Management
CONCLUSION: This study has presented an exhaustive overview of dietary therapies and functional foods that have undergone extensive research to explore their potential advantages in the management of diabetes. It looks into the role of gut health in glucose regulation, discusses the impact of different dietary elements on the course of diabetes, and evaluates how well functional foods can help with glycemic control. Furthermore, it investigates the mechanistic aspects of these therapies, including their influence on insulin sensitivity, β-cell activity, and inflammation. It deliberates on the limitations and potential pro...
Source: Current Diabetes Reviews - October 20, 2023 Category: Endocrinology Authors: Nirali Patel Susha Dinesh Sameer Sharma Source Type: research
Current Vaccination Practice in Diabetic (Diabetes I) Patients
Curr Diabetes Rev. 2023 Oct 6. doi: 10.2174/0115733998260361230927002739. Online ahead of print.ABSTRACTThe worldwide prevalence of diabetes, an endocrine condition, is rising quickly. The alarming rise of diabetes in recent years has emerged as a major contributor to premature death and illness among persons of working age. The potential use of immunomodulatory drugs to prevent diabetes has been a source of worry in light of recent advances in our understanding of the role of autoimmune responses in the development of diabetes. Vaccines can work in a variety of ways, including by eliminating autoreactive T-cells or by blo...
Source: Current Diabetes Reviews - October 20, 2023 Category: Endocrinology Authors: Yati Kumar Sonali Sundaram Deepika Yadav Source Type: research
Effect of the Theory-driven Educational Intervention on Self-Care Behavior and Glycosylated Hemoglobin Level in Patients with Type 2 Diabetes
CONCLUSION: Education based on the TPB was effective in improving the patients' self-care behavior and HbA1c index. Therefore, we suggest all medical centers to use the TPB as an effective and low-cost educational approach to improve diabetics' self-care behavior and health.PMID:37859319 | DOI:10.2174/0115733998253954230925050754 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - October 20, 2023 Category: Endocrinology Authors: Mojgan Pourmohammad Mina Maheri Hamid-Reza Khalkhali Fatemeh Moghaddam-Tabrizi Alireza Didarloo Source Type: research
From Gut to Glucose: A Comprehensive Review on Functional Foods and Dietary Interventions for Diabetes Management
CONCLUSION: This study has presented an exhaustive overview of dietary therapies and functional foods that have undergone extensive research to explore their potential advantages in the management of diabetes. It looks into the role of gut health in glucose regulation, discusses the impact of different dietary elements on the course of diabetes, and evaluates how well functional foods can help with glycemic control. Furthermore, it investigates the mechanistic aspects of these therapies, including their influence on insulin sensitivity, β-cell activity, and inflammation. It deliberates on the limitations and potential pro...
Source: Current Diabetes Reviews - October 20, 2023 Category: Endocrinology Authors: Nirali Patel Susha Dinesh Sameer Sharma Source Type: research
Current Vaccination Practice in Diabetic (Diabetes I) Patients
Curr Diabetes Rev. 2023 Oct 6. doi: 10.2174/0115733998260361230927002739. Online ahead of print.ABSTRACTThe worldwide prevalence of diabetes, an endocrine condition, is rising quickly. The alarming rise of diabetes in recent years has emerged as a major contributor to premature death and illness among persons of working age. The potential use of immunomodulatory drugs to prevent diabetes has been a source of worry in light of recent advances in our understanding of the role of autoimmune responses in the development of diabetes. Vaccines can work in a variety of ways, including by eliminating autoreactive T-cells or by blo...
Source: Current Diabetes Reviews - October 20, 2023 Category: Endocrinology Authors: Yati Kumar Sonali Sundaram Deepika Yadav Source Type: research
Effect of the Theory-driven Educational Intervention on Self-Care Behavior and Glycosylated Hemoglobin Level in Patients with Type 2 Diabetes
CONCLUSION: Education based on the TPB was effective in improving the patients' self-care behavior and HbA1c index. Therefore, we suggest all medical centers to use the TPB as an effective and low-cost educational approach to improve diabetics' self-care behavior and health.PMID:37859319 | DOI:10.2174/0115733998253954230925050754 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - October 20, 2023 Category: Endocrinology Authors: Mojgan Pourmohammad Mina Maheri Hamid-Reza Khalkhali Fatemeh Moghaddam-Tabrizi Alireza Didarloo Source Type: research
Recent Updates on Nanocarriers for Drug Delivery in Posterior Segment Diseases with Emphasis on Diabetic Retinopathy
Curr Diabetes Rev. 2023 Oct 17. doi: 10.2174/0115733998240053231009060654. Online ahead of print.ABSTRACTIn recent years, various conventional formulations have been used for the treatment and/or management of ocular medical conditions. Diabetic retinopathy, a microvascular disease of the retina, remains the leading cause of visual disability in patients with diabetes. Currently, for treating diabetic retinopathy, only intraocular, intravitreal, periocular injections, and laser photocoagulation are widely used. Frequent administration of these drugs by injections may lead to serious complications, including retinal detachm...
Source: Current Diabetes Reviews - October 19, 2023 Category: Endocrinology Authors: Ravi Parashar Amber Vyas Abhishek K Sah Narayan Hemnani Pugazhenthan Thangaraju Preeti K Suresh Source Type: research
