Effect of Novel Laser Shoe Photobiomodulation on Neuropathic Pain and Plantar Pressure Profile in Type 2 Diabetes Mellitus with Peripheral Neuropathy
CONCLUSION: We conclude that Novel laser shoe photobiomodulation using 'Laser Shoe' effectively reduces peripheral neuropathic pain. It is also effective in reducing average and maximum plantar pressure. Reduction in neuropathic pain and improvement in plantar pressure distribution can reduce further complications.PMID:38351691 | DOI:10.2174/0115733998244000231106040749 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - February 14, 2024 Category: Endocrinology Authors: G Arun Maiya Radhika Aditya Jadhav Hrishikesh Yadav K Manjunatha Hande H Harishchandra Hebbar Karthik Mohan Source Type: research

Pyrazole Scaffold: Potential PTP1B Inhibitors for Diabetes Treatment
This study aims to focus on the significance of pyrazole scaffold in medicinal chemistry, the impact of PTP1B in diabetes and the therapeutic approach of pyrazole scaffold to treat T2DM. A comprehensive analysis of the published literature in several pharmaceutical and medical databases, such as the Web of Science (WoS), PubMed, ResearchGate, ScienceDirect etc., were indeed successfully completed and classified accordingly. Results: As reviewed, the various derivatives of the pyrazole scaffold exhibited prominent PTP1B inhibitory activity. The result showed that derivatives of oxadiazole and dibenzyl amine, chloro substitu...
Source: Current Diabetes Reviews - February 14, 2024 Category: Endocrinology Authors: Kishor R Danao Vijayshri V Rokde Deweshri M Nandurkar Ujwala N Mahajan Source Type: research

Prevalence of Diabetes, Hypertension, and Obesity in Punjab: A Comparison between NFHS-4 and NFHS-5 Surveys
Curr Diabetes Rev. 2024 Feb 13. doi: 10.2174/0115733998285283240201045308. Online ahead of print.ABSTRACTDiseases that are caused by a person's everyday habits are known as lifestyle diseases. Habits that devoid people of their daily activities and direct them towards a sedentary lifestyle cause numerous health problems that can lead to non-communicable diseases. Noncommunicable diseases, or NCDs, kill more than 41 million individuals per year, accounting for 74% of all deaths worldwide. In India, 63% of all fatalities were attributed to NCDs in 2016, with 23% of those deaths being early. Compared to the current state of v...
Source: Current Diabetes Reviews - February 14, 2024 Category: Endocrinology Authors: Amandeep Kaur Ranjeet Kumar Amit Sharma Source Type: research

Effect of Novel Laser Shoe Photobiomodulation on Neuropathic Pain and Plantar Pressure Profile in Type 2 Diabetes Mellitus with Peripheral Neuropathy
CONCLUSION: We conclude that Novel laser shoe photobiomodulation using 'Laser Shoe' effectively reduces peripheral neuropathic pain. It is also effective in reducing average and maximum plantar pressure. Reduction in neuropathic pain and improvement in plantar pressure distribution can reduce further complications.PMID:38351691 | DOI:10.2174/0115733998244000231106040749 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - February 14, 2024 Category: Endocrinology Authors: G Arun Maiya Radhika Aditya Jadhav Hrishikesh Yadav K Manjunatha Hande H Harishchandra Hebbar Karthik Mohan Source Type: research

Pyrazole Scaffold: Potential PTP1B Inhibitors for Diabetes Treatment
This study aims to focus on the significance of pyrazole scaffold in medicinal chemistry, the impact of PTP1B in diabetes and the therapeutic approach of pyrazole scaffold to treat T2DM. A comprehensive analysis of the published literature in several pharmaceutical and medical databases, such as the Web of Science (WoS), PubMed, ResearchGate, ScienceDirect etc., were indeed successfully completed and classified accordingly. Results: As reviewed, the various derivatives of the pyrazole scaffold exhibited prominent PTP1B inhibitory activity. The result showed that derivatives of oxadiazole and dibenzyl amine, chloro substitu...
Source: Current Diabetes Reviews - February 14, 2024 Category: Endocrinology Authors: Kishor R Danao Vijayshri V Rokde Deweshri M Nandurkar Ujwala N Mahajan Source Type: research

Prevalence and Predictors of Diabetic Peripheral Neuropathy in Newly Diagnosed Type 2 Diabetes Mellitus Patients
CONCLUSION: The prevalence of DPN was high even in newly diagnosed T2DM and associated significantly with increasing age, HbA1C levels, TSH levels, hypertension, and reduced BMI. Earlier screening for DPN, along with aggressive control of glycemia, blood pressure, and hypothyroidism, may be beneficial.PMID:38347769 | DOI:10.2174/0115733998282818240125110248 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - February 13, 2024 Category: Endocrinology Authors: Pooja Jadhao Jayshree Swain Srijit Das Swayamsidha Mangaraj Surapaneni Lakshmi Sravya Source Type: research

Associated Factors Influencing Quality of Life and Knowledge Among Type 2 Diabetic Patients: A Cross-sectional Study
CONCLUSION: Irrespective of knowledge and educational background, the patient's age is influential in enhancing better QoL among type 2 diabetic patients.PMID:38347770 | DOI:10.2174/0115733998284163240129073837 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - February 13, 2024 Category: Endocrinology Authors: Mahmoud Alsaraireh Mahmoud Al-Kalaldeh Khaldoon Alnawafleh Doa'a Dwairej Wesam Almagharbeh Source Type: research

Unraveling the Therapeutic Potential of Muscle Strengthening Exercises for Reversing Diabetes Mellitus
CONCLUSION: Our analysis reveals promising evidence supporting the role of resistance training in diabetes mellitus reversal. Regular resistance exercise has been shown to improve glycemic control, insulin sensitivity, and muscle function in individuals with type 2 diabetes. Combining aerobic and resistance exercises appears to be more effective than single-mode training in managing blood glucose levels and enhancing overall metabolic health. However, Resistance training implementation challenges, as well as potential exercise contraindications in diabetic patients, warrant further studies.PMID:38318836 | DOI:10.2174/01157...
Source: Current Diabetes Reviews - February 6, 2024 Category: Endocrinology Authors: Haajeera Samsudeen Shree Pavithra D Krishnaveni Kandasamy Source Type: research

Diabetic Retinopathy - Pathophysiology to Treatment: A Review
This article has emphasized the molecular pathogenesis and treatment of DR.PMID:38315658 | DOI:10.2174/0115733998259940231105200251 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - February 5, 2024 Category: Endocrinology Authors: Randhir Dahiya Aditya Walia Jasleen Kaur Praveen Kumar Inderjeet Verma Nidhi Rani Source Type: research

Comparative Effectiveness of Oral Hypoglycemic Agents for Glycemic Control and Glycemic Variability in Patients with Type 2 Diabetes Mellitus: Using Flash Glucose Monitoring
CONCLUSION: The monotherapy group of SGLT2 inhibitors demonstrated glucose-lowering effects with reduced glycemic variability. Hence, optimum glycemic control is associated with decreased glycemic variability.PMID:38310479 | DOI:10.2174/0115733998267817231227102553 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - February 4, 2024 Category: Endocrinology Authors: Poongothai Venkatachalapathy Karthik Kumar Dos Alagarswamy Mohandoss Murali Munisamy Mohan Sellappan Source Type: research

Progress in Cardiac Magnetic Resonance Feature Tracking for Evaluating Myocardial Strain in Type-2 Diabetes Mellitus
Curr Diabetes Rev. 2024 Jan 16. doi: 10.2174/0115733998277127231211063107. Online ahead of print.ABSTRACTThe global prevalence of type-2 diabetes mellitus (T2DM) has caused harm to human health and economies. Cardiovascular disease is one main cause of T2DM mortality. Increased prevalence of diabetes and associated heart failure (HF) is common in older populations, so accurately evaluating heart-related injury and T2DM risk factors and conducting early intervention are important. Quantitative cardiovascular system imaging assessments, including functional imaging during cardiovascular disease treatment, are also important....
Source: Current Diabetes Reviews - February 4, 2024 Category: Endocrinology Authors: Li-Ting Shen Rui Shi Zhi-Gang Yang Yue Gao Yi-Ning Jiang Han Fang Chen-Yan Min Yuan Li Source Type: research

Association of the immunity genes with type 1 Diabetes Mellitus
Curr Diabetes Rev. 2024 Jan 8. doi: 10.2174/0115733998275617231218101116. Online ahead of print.ABSTRACTType 1 diabetes mellitus (T1D) is a complicated illness marked by the death of insulin-producing pancreatic beta cells, which ultimately leads to insulin insufficiency and hyperglycemia. T lymphocytes are considered to destroy pancreatic beta cells in the etiology of T1D as a result of hereditary and environmental factors. Although the latter factors are very important causes of T1D development, this disease is very genetically predisposed, so that there is a significant genetic component to T1D susceptibility. Among the...
Source: Current Diabetes Reviews - February 4, 2024 Category: Endocrinology Authors: Youssef Khaiz Najib Al Idrissi Mohammed Bakkali Samir Ahid Source Type: research

Glycemic Control in Patients with Type 1 Diabetes: Comparison of Holidays versus Schooldays
CONCLUSION: From the findings, it appears that children with T1D have good diabetes control during schooldays rather than during the holidays. To improve their glucose control during the holidays, these patients may also benefit from receiving greater attention and guidance.PMID:38310482 | DOI:10.2174/0115733998276061231117101716 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - February 4, 2024 Category: Endocrinology Authors: Ayman Al Hayek Asirvatham Alwin Robert Khuloud Almonea Mohamed Abdulaziz Al Dawish Source Type: research

Psychosocial Facilitators and Barriers to Type 2 Diabetes Management in Adults: A Meta-synthesis
CONCLUSION: The patients' experiences evident from this synthesis signify the crucial role of psychosocial factors in diabetes management and coping. This evidence emphasizes the need for integrated care so that psychosocial aspects are addressed by healthcare providers and behavioural health professionals, which may lead to the promotion of facilitators and the minimization of barriers.PMID:38310483 | DOI:10.2174/0115733998283436231207093250 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - February 4, 2024 Category: Endocrinology Authors: P Padma Sri Lekha E P Abdul Azeez Source Type: research

Therapeutic Interventions to Improve Static Balance in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis
CONCLUSION: There are a variety of effective training methods for improving static balance, and the choice of intervention to be applied goes beyond proven effectiveness, depending on reproducibility and/or financial cost.PMID:38310484 | DOI:10.2174/0115733998272338231213070602 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - February 4, 2024 Category: Endocrinology Authors: Ana Crisitna Marques Pedro Bruna Larysse Di ógenes Campelo Wellington Costa Souza Fernanda Mello da Silva Sous Vinicius Saura Cardoso Rebeca Barbosa da Rocha Source Type: research