The Possible Association of IL-6R Gene Polymorphisms in the Development of Diabetic Nephropathy
CONCLUSION: The results showed that the allele and genotype distribution frequencies of rs2228145 IL-6R gene polymorphism in patients with DN were significantly higher than in healthy individuals. Therefore, the presence of this polymorphism may be involved in the development of diabetic nephropathy in this population.PMID:37855360 | DOI:10.2174/0115733998245369231009111221 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - October 19, 2023 Category: Endocrinology Authors: Ebrahim Ebrat Seyyedeh Mina Hejazian Elham Ahmadian Sepideh Zununi Vahed Majid Mobasseri Mohammadreza Ardalan Source Type: research

Characteristics and biological properties of Imeglimin hydrochloride, A Novel antidiabetic agent: A systematic review
CONCLUSION: Therapeutic, pharmacological, and analytical considerations for the novel drug Imeglimin hydrochloride are discussed in this review.PMID:37855361 | DOI:10.2174/0115733998260331231009104035 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - October 19, 2023 Category: Endocrinology Authors: Jasira Sultan Nikhil Agarwal Sanjay Sharma Source Type: research

Pharmacoeconomic Aspects of Diabetes Mellitus: Outcomes and Analysis of Health Benefits Approach
Curr Diabetes Rev. 2023 Oct 11. doi: 10.2174/0115733998246567230924134603. Online ahead of print.ABSTRACTPharmacoeconomics is an important tool for investigating and restructuring healthcare policies. In India, recent statistical studies have shown that the number of diabetic patients is rapidly increasing in the rural, middle and upper-class settings. The aim of this review is to call attention towards the need to carry out pharmacoeconomic studies for diabetes mellitus and highlight the outcome of these studies on healthcare. A well-structured literature search from PubMed, Embase, Springer, ScienceDirect, and Cochrane w...
Source: Current Diabetes Reviews - October 16, 2023 Category: Endocrinology Authors: Ravinder Singh Jaura Suman Baishnab Saksham Sharma Honey Garg Thakur Gurjeet Singh Source Type: research

Analysis of Research Publications on Pharmacogenomics of Sulphonylurea - A Scientometric Study
This study analysed pharmacogenomics studies on sulfonylurea research publications using the Pubmed and Scopus databases. In the end, 65 publications from the years 2015 to 2021 were noticed. The objective of this study was to analyse these studies using scientometric tools, such as frequency counts, percentages, relative growth rates, doubling times, and collectively. A maximum of 19 (29.23%) research publications were contributed during the 2020 research period. The relative growth rate tends to decrease from 2015 to 2020 and the doubling time tends to increase and decrease after 2020. Up to 2 (3.08%) research publicatio...
Source: Current Diabetes Reviews - October 16, 2023 Category: Endocrinology Authors: Pugazhenthan Thangaraju Himanshu Nirmal Chandu Hemasri Velmurugan Pankaj Kumar Kannauje R Arun Kumar Source Type: research

An Overview of Diabetic Cardiomyopathy
Curr Diabetes Rev. 2023 Oct 12. doi: 10.2174/0115733998255538231001122639. Online ahead of print.ABSTRACTDiabetic cardiomyopathy (DCM) is a myocardial disorder that is characterised by structural and functional abnormalities of the heart muscle in the absence of hypertension, valvular heart disease, congenital heart defects, or coronary artery disease (CAD). After witnessing a particular form of cardiomyopathy in diabetic individuals, Rubler et al. came up with the moniker diabetic cardiomyopathy in 1972. Four stages of DCM are documented, and the American College of Cardiology/American Heart Association Stage and New York...
Source: Current Diabetes Reviews - October 16, 2023 Category: Endocrinology Authors: Abdul Quaiyoom Ranjeet Kumar Source Type: research