Risk Stratification in People with Diabetes for Fasting During Ramadan: Consensus from Arabic Association for the Study of Diabetes and Metabolism
CONCLUSION: Future research is warranted due to the controversial literature regarding the impact of fasting on certain comorbidities.PMID:37867270 | DOI:10.2174/0115733998249793231005105724 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - October 23, 2023 Category: Endocrinology Authors: Inass Shaltout Amr Mahmoud Abdelwahab Amr El Meligi Hany Hammad Shereen Abdelghaffar Atef Elbahry Nasser Taha Nehal Hamdy Elsaid Amr Gad Laila Hammouda Shaymaa Abdelmaboud Amin Roshdy Soliman Source Type: research

Research-based Analytical Procedures to Evaluate Diabetic Biomarkers and Related Parameters: In Vitro and In Vivo Methods
Conclusion: The development of new biomarkers is greatly facilitated by modern technology such as cell culture research, lipidomics study, microRNA biomarkers, machine learning techniques, and improved electron microscopies. These biomarkers do, however, have some usage restrictions. There is a critical need to find more accurate and sensitive biomarkers. With a few modifications, these biomarkers can be used with or even replace conventional markers of diabetes.PMID:37867271 | DOI:10.2174/0115733998252495231011182012 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - October 23, 2023 Category: Endocrinology Authors: Nadeem Rais Akash Ved Rizwan Ahmad Aashna Parveen Source Type: research

Thiazolidinedione as a Promising Medicinal Scaffold for the Treatment of Type 2 Diabetes
CONCLUSION: Thus, the potential of thiazolidinediones in terms of their chemical evolution, action on nuclear receptors, aldose reductase and free fatty acid receptor 1 is well established. The newer TZD analogues with better safety profiles and tolerability will soon be available in the market for common use without further delay.PMID:37867272 | DOI:10.2174/0115733998254798231005095627 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - October 23, 2023 Category: Endocrinology Authors: Gurvinder Singh Rajesh Kumar Desna Ds Manish Chaudhary Charanjit Kaur Navneet Khurrana Source Type: research

Hybrid CNN-LSTM for Predicting Diabetes: A Review
CONCLUSION: The CNN-LSTM model is a promising method for diabetes prediction, and compared with other deep-learning models, it is a reliable method.PMID:37867273 | DOI:10.2174/0115733998261151230925062430 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - October 23, 2023 Category: Endocrinology Authors: Soroush Soltanizadeh Seyedeh Somayeh Naghibi Source Type: research

Current Landscape of Various Techniques and Methods of Gene Therapy through CRISPR Cas9 along with its Pharmacological and Interventional Therapies in the Treatment of Type 2 Diabetes Mellitus
CONCLUSION: It can be concluded from the study that recent advancements in gene-editing technologies, such as CRISPR Cas9, have opened new avenues for the development of novel therapeutic approaches for T2DM. CRISPR Cas9 is a powerful tool that enables precise and targeted modifications of the genome.PMID:37867274 | DOI:10.2174/0115733998263079231011073803 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - October 23, 2023 Category: Endocrinology Authors: Pranay Wal Namra Aziz Harshit Prajapati Shashank Soni Ankita Wal Source Type: research

The Functional Role of microRNAs and mRNAs in Diabetic Kidney Disease: A Review
Curr Diabetes Rev. 2023 Oct 20. doi: 10.2174/0115733998270983231009094216. Online ahead of print.ABSTRACTDiabetes is a group of diseases marked by poor control of blood glucose levels. Diabetes mellitus (DM) occurs when pancreatic cells fail to make insulin, which is required to keep blood glucose levels stable, disorders, and so on. High glucose levels in the blood induce diabetic effects, which can cause catastrophic damage to bodily organs such as the eyes and lower extremities. Diabetes is classified into many forms, one of which is controlled by hyperglycemia or Diabetic Kidney Disease (DKD), and another that is not c...
Source: Current Diabetes Reviews - October 23, 2023 Category: Endocrinology Authors: Bhuvnesh Rai Jyotika Srivastava Pragati Saxena Source Type: research

Burden and Coping Strategies of Hypoglycemia in People with Diabetes
Curr Diabetes Rev. 2023 Oct 20. doi: 10.2174/0115733998271244231010100747. Online ahead of print.ABSTRACTHypoglycemia is a limiting adverse effect of glucose-lowering medications and particularly insulin replacement therapy. This review provides insights into the burden of hypoglycemia in the management of diabetes and outlines strategies available to reduce the risk of hypoglycemia and improve patients' well-being. People with type 1 diabetes are primarily affected by hypoglycemic episodes which are associated with direct physical harms like injuries and cardiac events as well as indirect psychosocial consequences includi...
Source: Current Diabetes Reviews - October 23, 2023 Category: Endocrinology Authors: Aris Liakos Thomas Karagiannis Ioannis Avgerinos Apostolos Tsapas Eleni Bekiari Source Type: research

A Review on Diabetic Retinopathy
Curr Diabetes Rev. 2023 Oct 20. doi: 10.2174/0115733998253672231011161400. Online ahead of print.ABSTRACTDiabetic retinopathy is a well-recognised microvascular complication of diabetes and is among the leading cause of blindness all over the world. Over the last decade, there have been advances in the diagnosis of diabetic retinopathy and diabetic macular edema. At the same time, newer therapies for the management of diabetic retinopathy have evolved. As a result of these advances, a decline in severe vision loss due to diabetes has been witnessed in some developing countries. However, there is a steady increase in the nu...
Source: Current Diabetes Reviews - October 23, 2023 Category: Endocrinology Authors: Vijender Kour Jayshree Swain Jaspreet Singh Hershdeep Singh Harvinder Kour Source Type: research

New Horizons in Diabetic Neuropathies: An Updated Review on their Pathology, Diagnosis, Mechanism, Screening Techniques, Pharmacological, and Future Approaches
CONCLUSION: This study highlights the probable involvement of several processes and pathways in the establishment of diabetic neuropathies and presents in-depth knowledge of new therapeutic approaches intended to stop, delay, or reverse different types of diabetic complications.PMID:37867268 | DOI:10.2174/0115733998242299231011181615 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - October 23, 2023 Category: Endocrinology Authors: Namra Aziz Biswajit Dash Pranay Wal Prachi Kumari Poonam Joshi Ankita Wal Source Type: research

Topical Anti-ulcerogenic Effect of the Beta-adrenergic Blockers on Diabetic Foot Ulcers: Recent Advances and Future Prospectives
CONCLUSION: There is a need to move forward from preclinical studies to clinical studies to analyze clinical findings to determine the effectiveness and safety of some beta-antagonists in diabetic foot ulcer treatment.PMID:37867269 | DOI:10.2174/0115733998249061231009093006 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - October 23, 2023 Category: Endocrinology Authors: Prateek Singh Shweta Sharma Pramod Kumar Sharma Aftab Alam Source Type: research

Risk Stratification in People with Diabetes for Fasting During Ramadan: Consensus from Arabic Association for the Study of Diabetes and Metabolism
CONCLUSION: Future research is warranted due to the controversial literature regarding the impact of fasting on certain comorbidities.PMID:37867270 | DOI:10.2174/0115733998249793231005105724 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - October 23, 2023 Category: Endocrinology Authors: Inass Shaltout Amr Mahmoud Abdelwahab Amr El Meligi Hany Hammad Shereen Abdelghaffar Atef Elbahry Nasser Taha Nehal Hamdy Elsaid Amr Gad Laila Hammouda Shaymaa Abdelmaboud Amin Roshdy Soliman Source Type: research

Research-based Analytical Procedures to Evaluate Diabetic Biomarkers and Related Parameters: In Vitro and In Vivo Methods
Conclusion: The development of new biomarkers is greatly facilitated by modern technology such as cell culture research, lipidomics study, microRNA biomarkers, machine learning techniques, and improved electron microscopies. These biomarkers do, however, have some usage restrictions. There is a critical need to find more accurate and sensitive biomarkers. With a few modifications, these biomarkers can be used with or even replace conventional markers of diabetes.PMID:37867271 | DOI:10.2174/0115733998252495231011182012 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - October 23, 2023 Category: Endocrinology Authors: Nadeem Rais Akash Ved Rizwan Ahmad Aashna Parveen Source Type: research

Thiazolidinedione as a Promising Medicinal Scaffold for the Treatment of Type 2 Diabetes
CONCLUSION: Thus, the potential of thiazolidinediones in terms of their chemical evolution, action on nuclear receptors, aldose reductase and free fatty acid receptor 1 is well established. The newer TZD analogues with better safety profiles and tolerability will soon be available in the market for common use without further delay.PMID:37867272 | DOI:10.2174/0115733998254798231005095627 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - October 23, 2023 Category: Endocrinology Authors: Gurvinder Singh Rajesh Kumar Desna Ds Manish Chaudhary Charanjit Kaur Navneet Khurrana Source Type: research

Hybrid CNN-LSTM for Predicting Diabetes: A Review
CONCLUSION: The CNN-LSTM model is a promising method for diabetes prediction, and compared with other deep-learning models, it is a reliable method.PMID:37867273 | DOI:10.2174/0115733998261151230925062430 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - October 23, 2023 Category: Endocrinology Authors: Soroush Soltanizadeh Seyedeh Somayeh Naghibi Source Type: research

Current Landscape of Various Techniques and Methods of Gene Therapy through CRISPR Cas9 along with its Pharmacological and Interventional Therapies in the Treatment of Type 2 Diabetes Mellitus
CONCLUSION: It can be concluded from the study that recent advancements in gene-editing technologies, such as CRISPR Cas9, have opened new avenues for the development of novel therapeutic approaches for T2DM. CRISPR Cas9 is a powerful tool that enables precise and targeted modifications of the genome.PMID:37867274 | DOI:10.2174/0115733998263079231011073803 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - October 23, 2023 Category: Endocrinology Authors: Pranay Wal Namra Aziz Harshit Prajapati Shashank Soni Ankita Wal Source Type: research