The Skin Microbiome in Atopic Dermatitis —a Potential Treatment Target?
AbstractPurpose of ReviewStaphylococcus aureus (S. aureus) frequently colonize the skin of patients with atopic dermatitis (AD). The abundance ofS. aureus increases during flares, accompanied by a reduction in bacterial diversity. This flare-associated imbalance in the cutaneous microflora (dysbiosis) correlates with disease severity. However, the causality of this association has not yet been fully established, and this review aims to further explore the relation between the skin microbiome and AD along with the clinical implications hereof.Recent FindingsRecently, it has been shown that the skin microbiome in clinically ...
Source: Current Dermatology Reports - November 8, 2018 Category: Dermatology Source Type: research
Use of Lasers in Wound Healing: How to Best Utilize Laser Technology to Prevent Scar Formation
AbstractPurpose of ReviewThe purpose of this review is to evaluate the efficacy of early intervention in wound healing on scar formation across multiple scar types and progressions. The types of scars consist of hypertrophic, atrophic, keloid, and contracture scars. The sources of scarring include inflammatory diseases (e.g., acne), surgery, burn, and trauma.Recent FindingsMinimal published research has been done regarding laser treatment in wound healing. Some studies have found promise in minor treatment of surgical wounds but few have sufficient clinical relevance. Recently, further studies have been conducted including...
Source: Current Dermatology Reports - November 5, 2018 Category: Dermatology Source Type: research
Updates on Immunotherapy for the Treatment of Skin Cancer
AbstractPurpose of ReviewSkin cancer is the most common malignancy in the USA, arising when mutated cells escape the host ’s natural immune surveillance. Immunotherapy helps boost the host’s immune system, augmenting the antitumor response. Given the ability of the immune system to evolve with a tumor’s evasive maneuvers, it is not surprising that immunotherapy has demonstrated durable clinical benefit in patient s with cancer, including certain types of skin cancers. Significant progress has been made with the recent development of immunotherapy for skin cancers.Recent FindingsHere, we review the literature on immun...
Source: Current Dermatology Reports - November 3, 2018 Category: Dermatology Source Type: research
Patient Education in Atopic Dermatitis: Why It Is Needed and How to Improve It
AbstractPurpose of ReviewDemonstrate the need and objectives of patient education in atopic dermatitis (AD), provide an overview of the most recent studies regarding patient education, and propose new approaches to improve educational programs.Recent FindingsDifferent models of patient education programs exist, and their structures depend on social and economic conditions. An active participation of patients is needed to improve new models of educational programs. Healthcare professionals who work with AD patients must have a comprehensive view of the many aspects involved in this disease, which includes psychological, env...
Source: Current Dermatology Reports - October 29, 2018 Category: Dermatology Source Type: research
Pediatric Inpatient Dermatology: New Insights on Severe Eruptions and Cutaneous Adverse Reactions
AbstractPurpose of ReviewThis manuscript reviews important advances in our understanding of severe eruptions and cutaneous adverse reactions in children.Recent FindingsThe latest research provides significant insights regarding severe cutaneous eruptions including coxsackievirus eruptions, mycoplasma-induced rash and mucositis, urticaria multiforme, erythema multiforme, and severe cutaneous adverse reactions. Recent literature expands our understanding of the incidence and cost, pathophysiology, and management considerations for pediatric patients with Stevens-Johnson syndrome and toxic epidermal necrolysis.SummaryPediatri...
Source: Current Dermatology Reports - October 25, 2018 Category: Dermatology Source Type: research
