The Hoax of Clean Beauty and Associated Allergens
AbstractPurpose of Review‘Clean beauty’ has experienced a notable surge in popularity among consumers. This movement is characterized by the replacement of ‘unsafe’ components with ‘natural’ or clean alternatives in personal care products and cosmetics. This review aims to examine the evidence and expert recomme ndations surrounding commonly implicated compounds by the clean beauty movement.Recent FindingsClean beauty products often contain potential allergens, and despite recent policy changes, there is still no standard definition of clean beauty. Recent studies demonstrated most products marketed as clean co...
Source: Current Dermatology Reports - August 15, 2023 Category: Dermatology Source Type: research
The Future of Patch Testing: Reimbursement Models, Workforce Shortages, and Negotiating in the House of Medicine
AbstractPurpose of ReviewPatch testing is critical to diagnosing allergic contact dermatitis; however, there are barriers that can prevent prompt comprehensive access, including those affecting reimbursement, insurer challenges, and workforce shortages.Recent FindingsMultiple reimbursement models exist within various practice types for patch testing. Insurer limits remain a barrier to comprehensive patch testing in many situations; however, advocacy in this area has led to some improvements. Workforce shortages, within medicine overall, as well as in dermatology and contact dermatitis specialists continue to be a concern. ...
Source: Current Dermatology Reports - August 15, 2023 Category: Dermatology Source Type: research
Recognition and Management of Necrotizing Neutrophilic Dermatoses
AbstractPurpose of ReviewNecrotizing neutrophilic dermatoses are frequently misdiagnosed as necrotizing fasciitis, resulting in inappropriate surgical intervention and amputation leading to unnecessary morbidity. This paper reviews recent literature to highlight clinical features, pearls for diagnosis, and potential treatment options.Recent FindingsNecrotizing neutrophilic dermatosis should be suspected in patients with classic cutaneous findings, presence of systemic symptoms, absence of an infectious source, and neutrophilic infiltrates on histopathology, particularly if necrotizing fasciitis is suspected but the patient...
Source: Current Dermatology Reports - August 7, 2023 Category: Dermatology Source Type: research
Correction to: Occupational Contact Dermatitis: An Individualized Approach to the Worker with Dermatitis
(Source: Current Dermatology Reports)
Source: Current Dermatology Reports - July 29, 2023 Category: Dermatology Source Type: research
Blood Flow ’s Effect on Percutaneous Absorption in Animal Models: A Systematic Review
AbstractIntroductionPercutaneous absorption is the deliverance of topically encountered molecules into the systemic circulation. This process can be harnessed therapeutically when prescribing topical medications, but is also the culprit of many toxicities. Many factors influence percutaneous absorption, an important yet understudied one being blood flow to the skin on which the chemical is applied.Purpose of ReviewThe aim of this work was to summarize the existing data investigating the relationship between blood flow and percutaneous absorption in animal models.MethodsPubMed and Embase databases were systematically search...
Source: Current Dermatology Reports - July 20, 2023 Category: Dermatology Source Type: research
Clinical Features and Management of Dermatologic Immune-Related Adverse Events for the Inpatient Dermatologist
AbstractPurpose of ReviewImmune checkpoint inhibitors (ICIs) have become a mainstay of oncologic treatment over the past decade. There are currently 11 ICIs approved by the U.S. Food and Drug Administration in the treatment of over a dozen malignancies. ICIs are associated with immune-related adverse events that can affect virtually any organ system. In some instances, these toxicities may lead to inpatient hospitalization and/or discontinuation of the ICI. This review highlights the clinical features and management of cutaneous toxicities most relevant to the inpatient dermatologist, including morbilliform eruptions, seve...
Source: Current Dermatology Reports - July 17, 2023 Category: Dermatology Source Type: research
Pruritus: An Approach to Diagnosis and Management for the Inpatient Dermatologist
AbstractPurpose of ReviewThis review provides a framework to categorize causes of pruritus that may present in the inpatient dermatology setting and highlights therapeutic options for these pruritic conditions.Recent FindingsVarious pruritogens have been implicated in dermatologic and systemic diseases, and itch characteristics may differ depending on etiology. Biologics have emerged as effective therapies for pruritus associated with dermatologic conditions. Novel treatment options for pruritus associated with systemic diseases include difelikefalin for CKD pruritus, butorphanol and ileal bile acid transporters for choles...
Source: Current Dermatology Reports - June 30, 2023 Category: Dermatology Source Type: research
Pseudomonas —Spectrum of Disease Presentations for the Inpatient Dermatologist
AbstractPurpose of ReviewPseudomonas aeruginosa-associated cutaneous dermatoses are reasons for consultation for the inpatient dermatologist. This review provides an overview of the spectrum of Pseudomonas-associated cutaneous diseases that may present in the inpatient setting along with the diagnostic work-up and clinical management.Recent FindingsPseudomonas aeruginosa infections are an ongoing healthcare concern due to its intrinsic and acquired antimicrobial resistance. The rising incidence of multi-drug resistantP. aeruginosa strains has led to the prioritization and development of effective drugs with increased effor...
Source: Current Dermatology Reports - June 9, 2023 Category: Dermatology Source Type: research
Skin Cancer, Climate Change, and Opportunities for Dermatologists
AbstractPurpose of ReviewSkin cancer is the most common cancer globally, and the incidence and prevalence of both melanoma and non-melanoma skin cancers has been increasing in recent decades, representing a rising number of disability-adjusted life years. This narrative review explores the interplay between climate change and the development of skin cancer, highlighting potential mechanistic links including increased UV radiation, tumorigenic effects of air pollutants such as phthalates and polycylic aromatic hydrocarbons stemming from anthropogenic practices, and sociobehavioral changes related to increasing ambient tempe...
Source: Current Dermatology Reports - June 7, 2023 Category: Dermatology Source Type: research
