Patch Testing and Immunosuppression: a Comprehensive Review
AbstractPurpose of ReviewTo provide an up-to-date synthesis of the literature on patch testing (PT) in patients undergoing immunosuppressive therapy or experiencing certain immunosuppressive diseases.Recent FindingsWith respect to immunosuppressive drugs, there is a risk of false-negative reactions if PT is conducted on patients taking prednisone at a dose greater than 10  mg daily. Topical corticosteroids, particularly high-potency formulations, could suppress positive reactions if applied to the test area in the days before PT. Other conventional systemic immunosuppressants have the potential to induce false-negative re...
Source: Current Dermatology Reports - October 30, 2021 Category: Dermatology Source Type: research

Social Media in Dermatology and an Overview of Popular Social Media Platforms
AbstractPurpose of ReviewSocial media provides an accessible and increasingly popular avenue for sharing healthcare information, networking, and outreach in dermatology. We provide an overview of prominent social media platforms, also known as applications or apps, as well as a discussion of their influence and implications for the field.Recent FindingsThe various collaborative features of Facebook, Twitter, Instagram, TikTok, YouTube, Snapchat, and other emerging platforms have proven appealing to organizations and users seeking dermatology-related content and medical advice. However, the potential for propagation of inac...
Source: Current Dermatology Reports - October 19, 2021 Category: Dermatology Source Type: research

Contact Dermatitis to Nail Cosmetics
AbstractPurpose of ReviewNail aesthetic procedures, particularly the fashion of nail sculpting, gel nails and long-lasting polishes, have been expanding over the last years, with an increasing number of cases of allergic contact dermatitis both in aestheticians and customers. Clinical suspicion and interpretation of nail cosmetics patch test results require a general knowledge of the main current manicure techniques and chemicals used.Recent FindingsAllergic contact dermatitis (ACD) to nail cosmetics, previously attributed mostly to tosylamide formaldehyde resin (TSFR), is now mainly caused by (meth)acrylates. In addition ...
Source: Current Dermatology Reports - October 19, 2021 Category: Dermatology Source Type: research

Management of Infectious Emergencies for the Inpatient Dermatologist
AbstractPurpose of ReviewThere are various dermatologic emergencies stemming from bacterial, viral, and fungal etiologies that can present in the inpatient setting. This review summarizes the pathogenesis and diagnosis of infections with cutaneous involvement and highlights new therapies.Recent FindingsClindamycin inhibits toxin formation and can be used as an adjunct therapy for the staphylococcal scalded syndrome. Isavuconazole therapy for mucormycosis infection is a less toxic alternative to amphotericin B.SummaryDiagnosis of these infections is primarily guided by high clinical suspicion and early recognition can preve...
Source: Current Dermatology Reports - October 6, 2021 Category: Dermatology Source Type: research

Inpatient Management of Psoriasis: A Current Perspective and Update for Clinicians
AbstractPurpose of ReviewThe purpose of this narrative review article is to describe the current literature on the psoriasis inpatient population, discuss considerations for admission, and provide updated recommendations for inpatient psoriasis workup, management, and post-discharge follow-up.Recent FindingsStudies report variable rates of psoriasis hospitalizations in the last decade even with the advent of highly efficacious outpatient therapies. Inequities in access to these therapies have resulted in disparities in the psoriasis inpatient population. Patients with severe variants of psoriasis, including generalized pus...
Source: Current Dermatology Reports - September 30, 2021 Category: Dermatology Source Type: research

Recognition and Management of Toxic Erythema of Chemotherapy for the Inpatient Dermatologist
AbstractPurpose of ReviewToxic erythema of chemotherapy is an umbrella term for several non-allergic cutaneous reactions to chemotherapeutic agents. Given the heterogenous range of presentations, we will review the differential diagnoses and treatment approaches, particularly for hospitalized patients.Recent FindingsEarly recognition, holding chemotherapy, or dose reduction and monitoring fluid balance for severely ill patients is the mainstay of treatment. Supportive care with topical steroids, emollients, and wound care have shown benefit.SummaryToxic erythema of chemotherapy can mimic several common eruptions seen in on...
Source: Current Dermatology Reports - September 30, 2021 Category: Dermatology Source Type: research

Inpatient Management of Psoriasis: A Current Perspective and Update for Clinicians
AbstractPurpose of ReviewThe purpose of this narrative review article is to describe the current literature on the psoriasis inpatient population, discuss considerations for admission, and provide updated recommendations for inpatient psoriasis workup, management, and post-discharge follow-up.Recent FindingsStudies report variable rates of psoriasis hospitalizations in the last decade even with the advent of highly efficacious outpatient therapies. Inequities in access to these therapies have resulted in disparities in the psoriasis inpatient population. Patients with severe variants of psoriasis, including generalized pus...
Source: Current Dermatology Reports - September 30, 2021 Category: Dermatology Source Type: research

Recognition and Management of Toxic Erythema of Chemotherapy for the Inpatient Dermatologist
AbstractPurpose of ReviewToxic erythema of chemotherapy is an umbrella term for several non-allergic cutaneous reactions to chemotherapeutic agents. Given the heterogenous range of presentations, we will review the differential diagnoses and treatment approaches, particularly for hospitalized patients.Recent FindingsEarly recognition, holding chemotherapy, or dose reduction and monitoring fluid balance for severely ill patients is the mainstay of treatment. Supportive care with topical steroids, emollients, and wound care have shown benefit.SummaryToxic erythema of chemotherapy can mimic several common eruptions seen in on...
Source: Current Dermatology Reports - September 30, 2021 Category: Dermatology Source Type: research

Occupational Contact Dermatitis: An Individualized Approach to the Worker with Dermatitis
AbstractPurpose of ReviewTo provide an up-to-date, customizable approach to the worker presenting with dermatitis.Recent FindingsOccupational contact dermatitis (OCD) is often a result of combined allergic, irritant, and endogenous factors. Potential causes of OCD can be categorized in 3 main groupings: workplace materials, personal protective equipment, and skin care. Although patterns of dermatitis may provide some indication of the etiological factor(s), patch testing remains essential in the diagnosis of allergic OCD. Management of OCD may require changes in workplace practices to reduce worker exposure to the causativ...
Source: Current Dermatology Reports - September 14, 2021 Category: Dermatology Source Type: research

Social Media and Ethical Challenges for the Dermatologist
AbstractPurpose of ReviewThe purpose of review is to provide guidance on the use of social media within the context of dermatology and discuss its ethical, professional, and legal implications in education, mentorship, networking, business, and clinical settings.Recent FindingsDespite its fundamental value as a means of communication and knowledge sharing, social media carries legal, ethical, and professional challenges. Healthcare providers have run into issues such as misinformation, conflicts of interest, and overstepping patient-physician boundaries when using social media. An interesting finding is that dermatologists...
Source: Current Dermatology Reports - September 13, 2021 Category: Dermatology Source Type: research