Neuroprotection of Thioredoxin1 in the brain
Curr Alzheimer Res. 2023 Aug 9. doi: 10.2174/1567205020666230809145041. Online ahead of print.ABSTRACTThioredoxin1 (Trx1) is a ubiquitous antioxidant protein that regulates the cell's redox status. Trx1's thiol redox activity protects neurons from various physiological processes that cause neuronal damage and neurodegeneration, including oxidative stress, apoptosis, and inflammation. Several studies have found that direct or indirect Trx1 regulation has neuroprotective effects in the brain, protecting against, preventing, or delaying neurodegenerative processes or brain traumas. This review focuses on the term neuroprotect...
Source: Current Alzheimer Research - August 10, 2023 Category: Neurology Authors: Roxana Noriega-Navarro Ricardo J Mart ínez-Tapia Juan L Osornio-Hern ández Lucia Landa-Navarro Luis O Xinastle-Castillo Abraham Landa Luz Navarro Source Type: research

Neural Oscillation Disorder in the Hippocampal CA1 Region of Different Alzheimer's Disease Mice
CONCLUSION: This study revealed neural network activity differences in oscillation power and cross-frequency coupling in the early stage of AD, providing a new perspective for developing biomarkers for early AD diagnosis.PMID:37559542 | DOI:10.2174/1567205020666230808122643 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - August 10, 2023 Category: Neurology Authors: Weiming Yuan Weijia Zhi Lizhen Ma Xiangjun Hu Qian Wang Yong Zou Lifeng Wang Source Type: research

Neuroprotection of Thioredoxin1 in the brain
Curr Alzheimer Res. 2023 Aug 9. doi: 10.2174/1567205020666230809145041. Online ahead of print.ABSTRACTThioredoxin1 (Trx1) is a ubiquitous antioxidant protein that regulates the cell's redox status. Trx1's thiol redox activity protects neurons from various physiological processes that cause neuronal damage and neurodegeneration, including oxidative stress, apoptosis, and inflammation. Several studies have found that direct or indirect Trx1 regulation has neuroprotective effects in the brain, protecting against, preventing, or delaying neurodegenerative processes or brain traumas. This review focuses on the term neuroprotect...
Source: Current Alzheimer Research - August 10, 2023 Category: Neurology Authors: Roxana Noriega-Navarro Ricardo J Mart ínez-Tapia Juan L Osornio-Hern ández Lucia Landa-Navarro Luis O Xinastle-Castillo Abraham Landa Luz Navarro Source Type: research

Neural Oscillation Disorder in the Hippocampal CA1 Region of Different Alzheimer's Disease Mice
CONCLUSION: This study revealed neural network activity differences in oscillation power and cross-frequency coupling in the early stage of AD, providing a new perspective for developing biomarkers for early AD diagnosis.PMID:37559542 | DOI:10.2174/1567205020666230808122643 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - August 10, 2023 Category: Neurology Authors: Weiming Yuan Weijia Zhi Lizhen Ma Xiangjun Hu Qian Wang Yong Zou Lifeng Wang Source Type: research

Neuroprotection of Thioredoxin1 in the brain
Curr Alzheimer Res. 2023 Aug 9. doi: 10.2174/1567205020666230809145041. Online ahead of print.ABSTRACTThioredoxin1 (Trx1) is a ubiquitous antioxidant protein that regulates the cell's redox status. Trx1's thiol redox activity protects neurons from various physiological processes that cause neuronal damage and neurodegeneration, including oxidative stress, apoptosis, and inflammation. Several studies have found that direct or indirect Trx1 regulation has neuroprotective effects in the brain, protecting against, preventing, or delaying neurodegenerative processes or brain traumas. This review focuses on the term neuroprotect...
Source: Current Alzheimer Research - August 10, 2023 Category: Neurology Authors: Roxana Noriega-Navarro Ricardo J Mart ínez-Tapia Juan L Osornio-Hern ández Lucia Landa-Navarro Luis O Xinastle-Castillo Abraham Landa Luz Navarro Source Type: research