Hybrid PET/MRI with Flutemetamol and FDG in Alzheimer's Disease Clinical Continuum
CONCLUSION: Integrated use of structural, metabolic, molecular (Aβ) and perfusion (CBF) parameters contribute to the discrimination of SCD, aMCI, and ADD.PMID:38050727 | DOI:10.2174/0115672050243131230925034334 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 5, 2023 Category: Neurology Authors: Lutfiye Ozlem Atay Esen Saka Umit Ozgur Akdemir Ezgi Yetim Erdem Balc ı Ethem Murat Arsava Mehmet Akif Topcuoglu Source Type: research
Hybrid PET/MRI with Flutemetamol and FDG in Alzheimer's Disease Clinical Continuum
CONCLUSION: Integrated use of structural, metabolic, molecular (Aβ) and perfusion (CBF) parameters contribute to the discrimination of SCD, aMCI, and ADD.PMID:38050727 | DOI:10.2174/0115672050243131230925034334 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 5, 2023 Category: Neurology Authors: Lutfiye Ozlem Atay Esen Saka Umit Ozgur Akdemir Ezgi Yetim Erdem Balc ı Ethem Murat Arsava Mehmet Akif Topcuoglu Source Type: research
An Online Shared Decision-making Intervention for Dementia Prevention: A Parallel-group Randomized Pilot Study
CONCLUSION: An online intervention providing psychoeducation and behavior change support was viewed positively by older adults. Results provide preliminary support for the CBSDM intervention's efficacy in promoting brain health in older adults.PMID:38047365 | DOI:10.2174/0115672050274126231120112158 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 4, 2023 Category: Neurology Authors: Raymond L Ownby Rosemary Davenport Source Type: research
Evidence of Clinical Efficacy and Pharmacological Mechanisms of Resveratrol in the Treatment of Alzheimer's Disease
CONCLUSION: While having a high safety profile, resveratrol has efficacy in AD patients to a certain extent, and more data are required to validate the efficacy of resveratrol for the treatment of AD in the future. Suppression of the PI3K signaling pathways could hold significant importance in the treatment of AD patients using resveratrol.PMID:38047366 | DOI:10.2174/0115672050272577231120060909 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 4, 2023 Category: Neurology Authors: Sian Jin Xuefeng Guan Dong-Yu Min Source Type: research
Blood Biomarkers Discriminate Cerebral Amyloid Status and Cognitive Diagnosis when Collected with ACD-A Anticoagulant
CONCLUSION: Our results suggest that the Aβ42/40 ratio is useful in discriminating clinician-rated elevated cerebral amyloid status and that NFL is useful for discriminating cognitive impairment status. These findings reinforce the growing body of evidence regarding the general utility of these biomarkers and extend their utility to plasma collected in a non-traditional anticoagulant.PMID:38047367 | DOI:10.2174/0115672050271523231111192725 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 4, 2023 Category: Neurology Authors: Zachary Green Paul Kueck Casey John Jeffrey Burns Jill Morris Source Type: research
An Online Shared Decision-making Intervention for Dementia Prevention: A Parallel-group Randomized Pilot Study
CONCLUSION: An online intervention providing psychoeducation and behavior change support was viewed positively by older adults. Results provide preliminary support for the CBSDM intervention's efficacy in promoting brain health in older adults.PMID:38047365 | DOI:10.2174/0115672050274126231120112158 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 4, 2023 Category: Neurology Authors: Raymond L Ownby Rosemary Davenport Source Type: research
Evidence of Clinical Efficacy and Pharmacological Mechanisms of Resveratrol in the Treatment of Alzheimer's Disease
CONCLUSION: While having a high safety profile, resveratrol has efficacy in AD patients to a certain extent, and more data are required to validate the efficacy of resveratrol for the treatment of AD in the future. Suppression of the PI3K signaling pathways could hold significant importance in the treatment of AD patients using resveratrol.PMID:38047366 | DOI:10.2174/0115672050272577231120060909 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 4, 2023 Category: Neurology Authors: Sian Jin Xuefeng Guan Dong-Yu Min Source Type: research
Blood Biomarkers Discriminate Cerebral Amyloid Status and Cognitive Diagnosis when Collected with ACD-A Anticoagulant
CONCLUSION: Our results suggest that the Aβ42/40 ratio is useful in discriminating clinician-rated elevated cerebral amyloid status and that NFL is useful for discriminating cognitive impairment status. These findings reinforce the growing body of evidence regarding the general utility of these biomarkers and extend their utility to plasma collected in a non-traditional anticoagulant.PMID:38047367 | DOI:10.2174/0115672050271523231111192725 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 4, 2023 Category: Neurology Authors: Zachary Green Paul Kueck Casey John Jeffrey Burns Jill Morris Source Type: research
The Association between Vitamin D Deficiency and Changes in Cognitive Functions in Chinese Older Adults: A Prospective Cohort Study
CONCLUSION: A higher frequency of VDD was associated with lower scores of FIQ, VIQ, PIQ and subtests on memory and executive function. Future randomized controlled trials are warranted to further verify the conclusions.PMID:37957919 | DOI:10.2174/0115672050266769231025060359 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - November 14, 2023 Category: Neurology Authors: Tongtong Li Chong Chen Jing Yuan Keming Zhang Meilin Zhang Huichao Zhao Xiaomin Wu Liping Zhu Guowei Huang Fei Ma Source Type: research
Neuroimaging Genetics and Network Analysis in Alzheimer's Disease Dementia
Curr Alzheimer Res. 2023 Nov 10. doi: 10.2174/0115672050265188231107072215. Online ahead of print.ABSTRACTThe issue of the genetics in brain imaging phenotypes serves as a crucial link between two distinct scientific fields: neuroimaging genetics (NG). The articles included here provide solid proof that this NG link has considerable synergy. There is a suitable collection of articles that offer a wide range of viewpoints on how genetic variations affect brain structure and function. They serve as illustrations of several study approaches used in contemporary genetics and neuroscience. Genome-wide association studies and ca...
Source: Current Alzheimer Research - November 14, 2023 Category: Neurology Authors: Seok Woo Moon Source Type: research
The Association between Vitamin D Deficiency and Changes in Cognitive Functions in Chinese Older Adults: A Prospective Cohort Study
CONCLUSION: A higher frequency of VDD was associated with lower scores of FIQ, VIQ, PIQ and subtests on memory and executive function. Future randomized controlled trials are warranted to further verify the conclusions.PMID:37957919 | DOI:10.2174/0115672050266769231025060359 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - November 14, 2023 Category: Neurology Authors: Tongtong Li Chong Chen Jing Yuan Keming Zhang Meilin Zhang Huichao Zhao Xiaomin Wu Liping Zhu Guowei Huang Fei Ma Source Type: research
Neuroimaging Genetics and Network Analysis in Alzheimer's Disease Dementia
Curr Alzheimer Res. 2023 Nov 10. doi: 10.2174/0115672050265188231107072215. Online ahead of print.ABSTRACTThe issue of the genetics in brain imaging phenotypes serves as a crucial link between two distinct scientific fields: neuroimaging genetics (NG). The articles included here provide solid proof that this NG link has considerable synergy. There is a suitable collection of articles that offer a wide range of viewpoints on how genetic variations affect brain structure and function. They serve as illustrations of several study approaches used in contemporary genetics and neuroscience. Genome-wide association studies and ca...
Source: Current Alzheimer Research - November 14, 2023 Category: Neurology Authors: Seok Woo Moon Source Type: research
The Association between Vitamin D Deficiency and Changes in Cognitive Functions in Chinese Older Adults: A Prospective Cohort Study
CONCLUSION: A higher frequency of VDD was associated with lower scores of FIQ, VIQ, PIQ and subtests on memory and executive function. Future randomized controlled trials are warranted to further verify the conclusions.PMID:37957919 | DOI:10.2174/0115672050266769231025060359 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - November 14, 2023 Category: Neurology Authors: Tongtong Li Chong Chen Jing Yuan Keming Zhang Meilin Zhang Huichao Zhao Xiaomin Wu Liping Zhu Guowei Huang Fei Ma Source Type: research
Neuroimaging Genetics and Network Analysis in Alzheimer's Disease Dementia
Curr Alzheimer Res. 2023 Nov 10. doi: 10.2174/0115672050265188231107072215. Online ahead of print.ABSTRACTThe issue of the genetics in brain imaging phenotypes serves as a crucial link between two distinct scientific fields: neuroimaging genetics (NG). The articles included here provide solid proof that this NG link has considerable synergy. There is a suitable collection of articles that offer a wide range of viewpoints on how genetic variations affect brain structure and function. They serve as illustrations of several study approaches used in contemporary genetics and neuroscience. Genome-wide association studies and ca...
Source: Current Alzheimer Research - November 14, 2023 Category: Neurology Authors: Seok Woo Moon Source Type: research
The Association between Vitamin D Deficiency and Changes in Cognitive Functions in Chinese Older Adults: A Prospective Cohort Study
CONCLUSION: A higher frequency of VDD was associated with lower scores of FIQ, VIQ, PIQ and subtests on memory and executive function. Future randomized controlled trials are warranted to further verify the conclusions.PMID:37957919 | DOI:10.2174/0115672050266769231025060359 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - November 14, 2023 Category: Neurology Authors: Tongtong Li Chong Chen Jing Yuan Keming Zhang Meilin Zhang Huichao Zhao Xiaomin Wu Liping Zhu Guowei Huang Fei Ma Source Type: research
