Uncovering the Impact of Aggrephagy in the Development of Alzheimer's Disease: Insights Into Diagnostic and Therapeutic Approaches from Machine Learning Analysis
CONCLUSION: Our findings not only contribute to a deeper understanding of the molecular mechanisms underlying AD but also offer valuable insights for drug development and clinical analysis. The limitation of our study is the limited sample size, and although AD-related genes were identified and some of the mechanisms elucidated, further experiments are needed to elucidate the more in-depth mechanisms of these characterized genes in the disease.PMID:38141185 | DOI:10.2174/0115672050280894231214063023 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 23, 2023 Category: Neurology Authors: Jiayu Xu Siqi Gou Xueyuan Huang Jieying Zhang Xuancheng Zhou Xiangjin Gong Jingwen Xiong Hao Chi Guanhu Yang Source Type: research

Uncovering the Impact of Aggrephagy in the Development of Alzheimer's Disease: Insights Into Diagnostic and Therapeutic Approaches from Machine Learning Analysis
CONCLUSION: Our findings not only contribute to a deeper understanding of the molecular mechanisms underlying AD but also offer valuable insights for drug development and clinical analysis. The limitation of our study is the limited sample size, and although AD-related genes were identified and some of the mechanisms elucidated, further experiments are needed to elucidate the more in-depth mechanisms of these characterized genes in the disease.PMID:38141185 | DOI:10.2174/0115672050280894231214063023 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 23, 2023 Category: Neurology Authors: Jiayu Xu Siqi Gou Xueyuan Huang Jieying Zhang Xuancheng Zhou Xiangjin Gong Jingwen Xiong Hao Chi Guanhu Yang Source Type: research

Uncovering the Impact of Aggrephagy in the Development of Alzheimer's Disease: Insights Into Diagnostic and Therapeutic Approaches from Machine Learning Analysis
CONCLUSION: Our findings not only contribute to a deeper understanding of the molecular mechanisms underlying AD but also offer valuable insights for drug development and clinical analysis. The limitation of our study is the limited sample size, and although AD-related genes were identified and some of the mechanisms elucidated, further experiments are needed to elucidate the more in-depth mechanisms of these characterized genes in the disease.PMID:38141185 | DOI:10.2174/0115672050280894231214063023 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 23, 2023 Category: Neurology Authors: Jiayu Xu Siqi Gou Xueyuan Huang Jieying Zhang Xuancheng Zhou Xiangjin Gong Jingwen Xiong Hao Chi Guanhu Yang Source Type: research

Hybrid PET/MRI with Flutemetamol and FDG in Alzheimer's Disease Clinical Continuum
CONCLUSION: Integrated use of structural, metabolic, molecular (Aβ) and perfusion (CBF) parameters contribute to the discrimination of SCD, aMCI, and ADD.PMID:38050727 | DOI:10.2174/0115672050243131230925034334 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 5, 2023 Category: Neurology Authors: Lutfiye Ozlem Atay Esen Saka Umit Ozgur Akdemir Ezgi Yetim Erdem Balc ı Ethem Murat Arsava Mehmet Akif Topcuoglu Source Type: research

Hybrid PET/MRI with Flutemetamol and FDG in Alzheimer's Disease Clinical Continuum
CONCLUSION: Integrated use of structural, metabolic, molecular (Aβ) and perfusion (CBF) parameters contribute to the discrimination of SCD, aMCI, and ADD.PMID:38050727 | DOI:10.2174/0115672050243131230925034334 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 5, 2023 Category: Neurology Authors: Lutfiye Ozlem Atay Esen Saka Umit Ozgur Akdemir Ezgi Yetim Erdem Balc ı Ethem Murat Arsava Mehmet Akif Topcuoglu Source Type: research

Hybrid PET/MRI with Flutemetamol and FDG in Alzheimer's Disease Clinical Continuum
CONCLUSION: Integrated use of structural, metabolic, molecular (Aβ) and perfusion (CBF) parameters contribute to the discrimination of SCD, aMCI, and ADD.PMID:38050727 | DOI:10.2174/0115672050243131230925034334 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 5, 2023 Category: Neurology Authors: Lutfiye Ozlem Atay Esen Saka Umit Ozgur Akdemir Ezgi Yetim Erdem Balc ı Ethem Murat Arsava Mehmet Akif Topcuoglu Source Type: research

Hybrid PET/MRI with Flutemetamol and FDG in Alzheimer's Disease Clinical Continuum
CONCLUSION: Integrated use of structural, metabolic, molecular (Aβ) and perfusion (CBF) parameters contribute to the discrimination of SCD, aMCI, and ADD.PMID:38050727 | DOI:10.2174/0115672050243131230925034334 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 5, 2023 Category: Neurology Authors: Lutfiye Ozlem Atay Esen Saka Umit Ozgur Akdemir Ezgi Yetim Erdem Balc ı Ethem Murat Arsava Mehmet Akif Topcuoglu Source Type: research

Hybrid PET/MRI with Flutemetamol and FDG in Alzheimer's Disease Clinical Continuum
CONCLUSION: Integrated use of structural, metabolic, molecular (Aβ) and perfusion (CBF) parameters contribute to the discrimination of SCD, aMCI, and ADD.PMID:38050727 | DOI:10.2174/0115672050243131230925034334 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 5, 2023 Category: Neurology Authors: Lutfiye Ozlem Atay Esen Saka Umit Ozgur Akdemir Ezgi Yetim Erdem Balc ı Ethem Murat Arsava Mehmet Akif Topcuoglu Source Type: research

Hybrid PET/MRI with Flutemetamol and FDG in Alzheimer's Disease Clinical Continuum
CONCLUSION: Integrated use of structural, metabolic, molecular (Aβ) and perfusion (CBF) parameters contribute to the discrimination of SCD, aMCI, and ADD.PMID:38050727 | DOI:10.2174/0115672050243131230925034334 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 5, 2023 Category: Neurology Authors: Lutfiye Ozlem Atay Esen Saka Umit Ozgur Akdemir Ezgi Yetim Erdem Balc ı Ethem Murat Arsava Mehmet Akif Topcuoglu Source Type: research

Hybrid PET/MRI with Flutemetamol and FDG in Alzheimer's Disease Clinical Continuum
CONCLUSION: Integrated use of structural, metabolic, molecular (Aβ) and perfusion (CBF) parameters contribute to the discrimination of SCD, aMCI, and ADD.PMID:38050727 | DOI:10.2174/0115672050243131230925034334 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 5, 2023 Category: Neurology Authors: Lutfiye Ozlem Atay Esen Saka Umit Ozgur Akdemir Ezgi Yetim Erdem Balc ı Ethem Murat Arsava Mehmet Akif Topcuoglu Source Type: research

Hybrid PET/MRI with Flutemetamol and FDG in Alzheimer's Disease Clinical Continuum
CONCLUSION: Integrated use of structural, metabolic, molecular (Aβ) and perfusion (CBF) parameters contribute to the discrimination of SCD, aMCI, and ADD.PMID:38050727 | DOI:10.2174/0115672050243131230925034334 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 5, 2023 Category: Neurology Authors: Lutfiye Ozlem Atay Esen Saka Umit Ozgur Akdemir Ezgi Yetim Erdem Balc ı Ethem Murat Arsava Mehmet Akif Topcuoglu Source Type: research

Hybrid PET/MRI with Flutemetamol and FDG in Alzheimer's Disease Clinical Continuum
CONCLUSION: Integrated use of structural, metabolic, molecular (Aβ) and perfusion (CBF) parameters contribute to the discrimination of SCD, aMCI, and ADD.PMID:38050727 | DOI:10.2174/0115672050243131230925034334 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 5, 2023 Category: Neurology Authors: Lutfiye Ozlem Atay Esen Saka Umit Ozgur Akdemir Ezgi Yetim Erdem Balc ı Ethem Murat Arsava Mehmet Akif Topcuoglu Source Type: research

Hybrid PET/MRI with Flutemetamol and FDG in Alzheimer's Disease Clinical Continuum
CONCLUSION: Integrated use of structural, metabolic, molecular (Aβ) and perfusion (CBF) parameters contribute to the discrimination of SCD, aMCI, and ADD.PMID:38050727 | DOI:10.2174/0115672050243131230925034334 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 5, 2023 Category: Neurology Authors: Lutfiye Ozlem Atay Esen Saka Umit Ozgur Akdemir Ezgi Yetim Erdem Balc ı Ethem Murat Arsava Mehmet Akif Topcuoglu Source Type: research

Hybrid PET/MRI with Flutemetamol and FDG in Alzheimer's Disease Clinical Continuum
CONCLUSION: Integrated use of structural, metabolic, molecular (Aβ) and perfusion (CBF) parameters contribute to the discrimination of SCD, aMCI, and ADD.PMID:38050727 | DOI:10.2174/0115672050243131230925034334 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 5, 2023 Category: Neurology Authors: Lutfiye Ozlem Atay Esen Saka Umit Ozgur Akdemir Ezgi Yetim Erdem Balc ı Ethem Murat Arsava Mehmet Akif Topcuoglu Source Type: research

Hybrid PET/MRI with Flutemetamol and FDG in Alzheimer's Disease Clinical Continuum
CONCLUSION: Integrated use of structural, metabolic, molecular (Aβ) and perfusion (CBF) parameters contribute to the discrimination of SCD, aMCI, and ADD.PMID:38050727 | DOI:10.2174/0115672050243131230925034334 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - December 5, 2023 Category: Neurology Authors: Lutfiye Ozlem Atay Esen Saka Umit Ozgur Akdemir Ezgi Yetim Erdem Balc ı Ethem Murat Arsava Mehmet Akif Topcuoglu Source Type: research