Molecular imaging of bacterial biofilms-a systematic review
Crit Rev Microbiol. 2023 Jul 15:1-22. doi: 10.1080/1040841X.2023.2223704. Online ahead of print.ABSTRACTThe formation of bacterial biofilms in the human body and on medical devices is a serious human health concern. Infections related to bacterial biofilms are often chronic and difficult to treat. Detailed information on biofilm formation and composition over time is essential for a fundamental understanding of the underlying mechanisms of biofilm formation and its response to anti-biofilm therapy. However, information on the chemical composition, structural components of biofilms, and molecular interactions regarding meta...
Source: Critical Reviews in Microbiology - July 15, 2023 Category: Microbiology Authors: S W G van Hoogstraten C Kuik J J C Arts B Cillero-Pastor Source Type: research
Are anaerobic fungi crucial hidden players of microbiomes in anoxic environment?
Crit Rev Microbiol. 2023 Jul 15:1-24. doi: 10.1080/1040841X.2023.2224425. Online ahead of print.ABSTRACTAnaerobic fungi are known to migrate and establish a 3D network of biofilms (microbiomes) and live invisible in the rumen and terrestrial subsurface, deep-sea - marine, and anoxic environment. They deserve our attention to understand anoxic fungal ecology and functions and develop new products and solutions. Such fungi activate unique genes to produce various polysaccharidases deemed essential for degrading plants' lignocellulosic materials. Nutrient release, recycling, and physical support by anaerobic fungi are crucial...
Source: Critical Reviews in Microbiology - July 15, 2023 Category: Microbiology Authors: Enamul Hoque Johannes Fritscher Source Type: research
Type IV pili are involved in phenotypes associated with < em > Clostridioides difficile < /em > pathogenesis
Crit Rev Microbiol. 2023 Jul 15:1-9. doi: 10.1080/1040841X.2023.2235002. Online ahead of print.ABSTRACTClostridioides difficile is a Gram-positive, spore-forming, rod-shaped, obligate anaerobe that is the leading cause of antibiotic-associated diarrhea. Type IV pili (T4P) are elongated appendages on the surface of C. difficile that are polymerized from many pilin proteins. T4P play an important role in C. difficile adherence and particularly in its persistence in the host intestine. Recent studies have shown that T4P promote C. difficile aggregation, surface motility, and biofilm formation, which may enhance its pathogenic...
Source: Critical Reviews in Microbiology - July 15, 2023 Category: Microbiology Authors: Zirou Ouyang Hanlin Zhao Min Zhao Yaxuan Yang Jianhong Zhao Source Type: research
Molecular imaging of bacterial biofilms-a systematic review
Crit Rev Microbiol. 2023 Jul 15:1-22. doi: 10.1080/1040841X.2023.2223704. Online ahead of print.ABSTRACTThe formation of bacterial biofilms in the human body and on medical devices is a serious human health concern. Infections related to bacterial biofilms are often chronic and difficult to treat. Detailed information on biofilm formation and composition over time is essential for a fundamental understanding of the underlying mechanisms of biofilm formation and its response to anti-biofilm therapy. However, information on the chemical composition, structural components of biofilms, and molecular interactions regarding meta...
Source: Critical Reviews in Microbiology - July 15, 2023 Category: Microbiology Authors: S W G van Hoogstraten C Kuik J J C Arts B Cillero-Pastor Source Type: research
Are anaerobic fungi crucial hidden players of microbiomes in anoxic environment?
Crit Rev Microbiol. 2023 Jul 15:1-24. doi: 10.1080/1040841X.2023.2224425. Online ahead of print.ABSTRACTAnaerobic fungi are known to migrate and establish a 3D network of biofilms (microbiomes) and live invisible in the rumen and terrestrial subsurface, deep-sea - marine, and anoxic environment. They deserve our attention to understand anoxic fungal ecology and functions and develop new products and solutions. Such fungi activate unique genes to produce various polysaccharidases deemed essential for degrading plants' lignocellulosic materials. Nutrient release, recycling, and physical support by anaerobic fungi are crucial...
Source: Critical Reviews in Microbiology - July 15, 2023 Category: Microbiology Authors: Enamul Hoque Johannes Fritscher Source Type: research
Type IV pili are involved in phenotypes associated with < em > Clostridioides difficile < /em > pathogenesis
Crit Rev Microbiol. 2023 Jul 15:1-9. doi: 10.1080/1040841X.2023.2235002. Online ahead of print.ABSTRACTClostridioides difficile is a Gram-positive, spore-forming, rod-shaped, obligate anaerobe that is the leading cause of antibiotic-associated diarrhea. Type IV pili (T4P) are elongated appendages on the surface of C. difficile that are polymerized from many pilin proteins. T4P play an important role in C. difficile adherence and particularly in its persistence in the host intestine. Recent studies have shown that T4P promote C. difficile aggregation, surface motility, and biofilm formation, which may enhance its pathogenic...
Source: Critical Reviews in Microbiology - July 15, 2023 Category: Microbiology Authors: Zirou Ouyang Hanlin Zhao Min Zhao Yaxuan Yang Jianhong Zhao Source Type: research
Molecular imaging of bacterial biofilms-a systematic review
Crit Rev Microbiol. 2023 Jul 15:1-22. doi: 10.1080/1040841X.2023.2223704. Online ahead of print.ABSTRACTThe formation of bacterial biofilms in the human body and on medical devices is a serious human health concern. Infections related to bacterial biofilms are often chronic and difficult to treat. Detailed information on biofilm formation and composition over time is essential for a fundamental understanding of the underlying mechanisms of biofilm formation and its response to anti-biofilm therapy. However, information on the chemical composition, structural components of biofilms, and molecular interactions regarding meta...
Source: Critical Reviews in Microbiology - July 15, 2023 Category: Microbiology Authors: S W G van Hoogstraten C Kuik J J C Arts B Cillero-Pastor Source Type: research
Are anaerobic fungi crucial hidden players of microbiomes in anoxic environment?
Crit Rev Microbiol. 2023 Jul 15:1-24. doi: 10.1080/1040841X.2023.2224425. Online ahead of print.ABSTRACTAnaerobic fungi are known to migrate and establish a 3D network of biofilms (microbiomes) and live invisible in the rumen and terrestrial subsurface, deep-sea - marine, and anoxic environment. They deserve our attention to understand anoxic fungal ecology and functions and develop new products and solutions. Such fungi activate unique genes to produce various polysaccharidases deemed essential for degrading plants' lignocellulosic materials. Nutrient release, recycling, and physical support by anaerobic fungi are crucial...
Source: Critical Reviews in Microbiology - July 15, 2023 Category: Microbiology Authors: Enamul Hoque Johannes Fritscher Source Type: research
Type IV pili are involved in phenotypes associated with < em > Clostridioides difficile < /em > pathogenesis
Crit Rev Microbiol. 2023 Jul 15:1-9. doi: 10.1080/1040841X.2023.2235002. Online ahead of print.ABSTRACTClostridioides difficile is a Gram-positive, spore-forming, rod-shaped, obligate anaerobe that is the leading cause of antibiotic-associated diarrhea. Type IV pili (T4P) are elongated appendages on the surface of C. difficile that are polymerized from many pilin proteins. T4P play an important role in C. difficile adherence and particularly in its persistence in the host intestine. Recent studies have shown that T4P promote C. difficile aggregation, surface motility, and biofilm formation, which may enhance its pathogenic...
Source: Critical Reviews in Microbiology - July 15, 2023 Category: Microbiology Authors: Zirou Ouyang Hanlin Zhao Min Zhao Yaxuan Yang Jianhong Zhao Source Type: research
Targeting the gut microbiota to alleviate chemotherapy-induced toxicity in cancer
Crit Rev Microbiol. 2023 Jul 13:1-17. doi: 10.1080/1040841X.2023.2233605. Online ahead of print.ABSTRACTDespite ongoing breakthroughs in novel anticancer therapies, chemotherapy remains a mainstream therapeutic modality in different types of cancer. Unfortunately, chemotherapy-related toxicity (CRT) often leads to dose limitation, and even results in treatment termination. Over the past few years, accumulating evidence has indicated that the gut microbiota is extensively engaged in various toxicities initiated by chemotherapeutic drugs, either directly or indirectly. The gut microbiota can now be targeted to reduce the tox...
Source: Critical Reviews in Microbiology - July 13, 2023 Category: Microbiology Authors: Yaning Xu Haiyan Du Yuchun Chen Chong Ma Qian Zhang Hao Li Zhiyong Xie Yanjun Hong Source Type: research
Targeting the gut microbiota to alleviate chemotherapy-induced toxicity in cancer
Crit Rev Microbiol. 2023 Jul 13:1-17. doi: 10.1080/1040841X.2023.2233605. Online ahead of print.ABSTRACTDespite ongoing breakthroughs in novel anticancer therapies, chemotherapy remains a mainstream therapeutic modality in different types of cancer. Unfortunately, chemotherapy-related toxicity (CRT) often leads to dose limitation, and even results in treatment termination. Over the past few years, accumulating evidence has indicated that the gut microbiota is extensively engaged in various toxicities initiated by chemotherapeutic drugs, either directly or indirectly. The gut microbiota can now be targeted to reduce the tox...
Source: Critical Reviews in Microbiology - July 13, 2023 Category: Microbiology Authors: Yanin Xu Haiyan Du Yuchun Chen Chong Ma Qian Zhang Hao Li Zhiyong Xie Yanjun Hong Source Type: research
Interplay between lipid metabolism, lipid droplets and RNA virus replication
Crit Rev Microbiol. 2023 Jun 22:1-25. doi: 10.1080/1040841X.2023.2224424. Online ahead of print.ABSTRACTLipids play essential roles in the cell as components of cellular membranes, signaling molecules, and energy storage sources. Lipid droplets are cellular organelles composed of neutral lipids, such as triglycerides and cholesterol esters, and are also considered as cellular energy reserves, yet new functions have been recently associated with these structures, such as regulators of oxidative stress and cellular lipotoxicity, as well as modulators of pathogen infection through immune regulation. Lipid metabolism and lipid...
Source: Critical Reviews in Microbiology - June 22, 2023 Category: Microbiology Authors: M ónica A Farías Benjam ín Diethelm-Varela Alexis M Kalergis Pablo A Gonz ález Source Type: research
Interplay between lipid metabolism, lipid droplets and RNA virus replication
Crit Rev Microbiol. 2023 Jun 22:1-25. doi: 10.1080/1040841X.2023.2224424. Online ahead of print.ABSTRACTLipids play essential roles in the cell as components of cellular membranes, signaling molecules, and energy storage sources. Lipid droplets are cellular organelles composed of neutral lipids, such as triglycerides and cholesterol esters, and are also considered as cellular energy reserves, yet new functions have been recently associated with these structures, such as regulators of oxidative stress and cellular lipotoxicity, as well as modulators of pathogen infection through immune regulation. Lipid metabolism and lipid...
Source: Critical Reviews in Microbiology - June 22, 2023 Category: Microbiology Authors: M ónica A Farías Benjam ín Diethelm-Varela Alexis M Kalergis Pablo A Gonz ález Source Type: research
Interplay between lipid metabolism, lipid droplets and RNA virus replication
Crit Rev Microbiol. 2023 Jun 22:1-25. doi: 10.1080/1040841X.2023.2224424. Online ahead of print.ABSTRACTLipids play essential roles in the cell as components of cellular membranes, signaling molecules, and energy storage sources. Lipid droplets are cellular organelles composed of neutral lipids, such as triglycerides and cholesterol esters, and are also considered as cellular energy reserves, yet new functions have been recently associated with these structures, such as regulators of oxidative stress and cellular lipotoxicity, as well as modulators of pathogen infection through immune regulation. Lipid metabolism and lipid...
Source: Critical Reviews in Microbiology - June 22, 2023 Category: Microbiology Authors: M ónica A Farías Benjam ín Diethelm-Varela Alexis M Kalergis Pablo A Gonz ález Source Type: research
Interplay between lipid metabolism, lipid droplets and RNA virus replication
Crit Rev Microbiol. 2023 Jun 22:1-25. doi: 10.1080/1040841X.2023.2224424. Online ahead of print.ABSTRACTLipids play essential roles in the cell as components of cellular membranes, signaling molecules, and energy storage sources. Lipid droplets are cellular organelles composed of neutral lipids, such as triglycerides and cholesterol esters, and are also considered as cellular energy reserves, yet new functions have been recently associated with these structures, such as regulators of oxidative stress and cellular lipotoxicity, as well as modulators of pathogen infection through immune regulation. Lipid metabolism and lipid...
Source: Critical Reviews in Microbiology - June 22, 2023 Category: Microbiology Authors: M ónica A Farías Benjam ín Diethelm-Varela Alexis M Kalergis Pablo A Gonz ález Source Type: research
