Sensitive delivery systems and novel encapsulation technologies for live biotherapeutic products and probiotics
Crit Rev Microbiol. 2023 Apr 19:1-14. doi: 10.1080/1040841X.2023.2202237. Online ahead of print.ABSTRACTLive biotherapeutic product (LBP), a type of biological product, holds promise for the prevention or treatment of metabolic disease and pathogenic infection. Probiotics are live microorganisms that improve the intestinal microbial balance and beneficially affect the health of the host when ingested in sufficient numbers. These biological products possess the advantages of inhibition of pathogens, degradation of toxins, and modulation of immunity. The application of LBP and probiotic delivery systems has attracted great i...
Source: Critical Reviews in Microbiology - April 19, 2023 Category: Microbiology Authors: Shuang Li Yi-Xuan Zhang Source Type: research
Long-Term effects of COVID-19: a review of current perspectives and mechanistic insights
Crit Rev Microbiol. 2023 Apr 19:1-14. doi: 10.1080/1040841X.2023.2190405. Online ahead of print.ABSTRACTAlthough SARS-CoV-2, responsible for COVID-19, is primarily a respiratory infection, a broad spectrum of cardiac, pulmonary, neurologic, and metabolic complications can occur. More than 50 long-term symptoms of COVID-19 have been described, and as many as 80% of patients may develop ≥1 long-term symptom. To summarize current perspectives of long-term sequelae of COVID-19, we conducted a PubMed search describing the long-term cardiovascular, pulmonary, gastrointestinal, and neurologic effects post-SARS-CoV-2 infection a...
Source: Critical Reviews in Microbiology - April 19, 2023 Category: Microbiology Authors: Christian Lenz Mary P E Slack Kimberly M Shea Ralf Ren é Reinert B ülent N Taysi David L Swerdlow Source Type: research
Sensitive delivery systems and novel encapsulation technologies for live biotherapeutic products and probiotics
Crit Rev Microbiol. 2023 Apr 19:1-14. doi: 10.1080/1040841X.2023.2202237. Online ahead of print.ABSTRACTLive biotherapeutic product (LBP), a type of biological product, holds promise for the prevention or treatment of metabolic disease and pathogenic infection. Probiotics are live microorganisms that improve the intestinal microbial balance and beneficially affect the health of the host when ingested in sufficient numbers. These biological products possess the advantages of inhibition of pathogens, degradation of toxins, and modulation of immunity. The application of LBP and probiotic delivery systems has attracted great i...
Source: Critical Reviews in Microbiology - April 19, 2023 Category: Microbiology Authors: Shuang Li Yi-Xuan Zhang Source Type: research
Long-Term effects of COVID-19: a review of current perspectives and mechanistic insights
Crit Rev Microbiol. 2023 Apr 19:1-14. doi: 10.1080/1040841X.2023.2190405. Online ahead of print.ABSTRACTAlthough SARS-CoV-2, responsible for COVID-19, is primarily a respiratory infection, a broad spectrum of cardiac, pulmonary, neurologic, and metabolic complications can occur. More than 50 long-term symptoms of COVID-19 have been described, and as many as 80% of patients may develop ≥1 long-term symptom. To summarize current perspectives of long-term sequelae of COVID-19, we conducted a PubMed search describing the long-term cardiovascular, pulmonary, gastrointestinal, and neurologic effects post-SARS-CoV-2 infection a...
Source: Critical Reviews in Microbiology - April 19, 2023 Category: Microbiology Authors: Christian Lenz Mary P E Slack Kimberly M Shea Ralf Ren é Reinert B ülent N Taysi David L Swerdlow Source Type: research
Engineered probiotics as live biotherapeutics for diagnosis and treatment of human diseases
Crit Rev Microbiol. 2023 Mar 22:1-15. doi: 10.1080/1040841X.2023.2190392. Online ahead of print.ABSTRACTThe use of probiotics to regulate the intestinal microbiota to prevent and treat a large number of disorders and diseases has been an international research hotspot. Although conventional probiotics have a certain regulatory role in nutrient metabolism, inhibiting pathogens, inducing immune regulation, and maintaining intestinal epithelial barrier function, they are unable to treat certain diseases. In recent years, aided by the continuous development of synthetic biology, engineering probiotics with desired characterist...
Source: Critical Reviews in Microbiology - March 22, 2023 Category: Microbiology Authors: Jiao Meng Shufan Liu Xin Wu Source Type: research
