Outer membrane proteins and vesicles as promising vaccine candidates against < em > Vibrio < /em > spp. infections
Crit Rev Microbiol. 2023 Jun 5:1-17. doi: 10.1080/1040841X.2023.2212072. Online ahead of print.ABSTRACTIndiscriminate use of antibiotics to treat bacterial infections has brought unmanageable antibiotic-resistant strains into existence. Vibrio spp. represents one such gram-negative enteric pathogenic group with more than 100 species, infecting humans and fish. The Vibrio spp. is demarcated into two groups, one that causes cholera and the other producing non-cholera or vibriosis infections. People who encounter contaminated water are at risk, but young children and pregnant women are the most vulnerable. Though controllable...
Source: Critical Reviews in Microbiology - June 5, 2023 Category: Microbiology Authors: Brijeshwar Singh Surbhi Jaiswal Prashant Kodgire Source Type: research
Outer membrane proteins and vesicles as promising vaccine candidates against < em > Vibrio < /em > spp. infections
Crit Rev Microbiol. 2023 Jun 5:1-17. doi: 10.1080/1040841X.2023.2212072. Online ahead of print.ABSTRACTIndiscriminate use of antibiotics to treat bacterial infections has brought unmanageable antibiotic-resistant strains into existence. Vibrio spp. represents one such gram-negative enteric pathogenic group with more than 100 species, infecting humans and fish. The Vibrio spp. is demarcated into two groups, one that causes cholera and the other producing non-cholera or vibriosis infections. People who encounter contaminated water are at risk, but young children and pregnant women are the most vulnerable. Though controllable...
Source: Critical Reviews in Microbiology - June 5, 2023 Category: Microbiology Authors: Brijeshwar Singh Surbhi Jaiswal Prashant Kodgire Source Type: research
Outer membrane proteins and vesicles as promising vaccine candidates against < em > Vibrio < /em > spp. infections
Crit Rev Microbiol. 2023 Jun 5:1-17. doi: 10.1080/1040841X.2023.2212072. Online ahead of print.ABSTRACTIndiscriminate use of antibiotics to treat bacterial infections has brought unmanageable antibiotic-resistant strains into existence. Vibrio spp. represents one such gram-negative enteric pathogenic group with more than 100 species, infecting humans and fish. The Vibrio spp. is demarcated into two groups, one that causes cholera and the other producing non-cholera or vibriosis infections. People who encounter contaminated water are at risk, but young children and pregnant women are the most vulnerable. Though controllable...
Source: Critical Reviews in Microbiology - June 5, 2023 Category: Microbiology Authors: Brijeshwar Singh Surbhi Jaiswal Prashant Kodgire Source Type: research
Outer membrane proteins and vesicles as promising vaccine candidates against < em > Vibrio < /em > spp. infections
Crit Rev Microbiol. 2023 Jun 5:1-17. doi: 10.1080/1040841X.2023.2212072. Online ahead of print.ABSTRACTIndiscriminate use of antibiotics to treat bacterial infections has brought unmanageable antibiotic-resistant strains into existence. Vibrio spp. represents one such gram-negative enteric pathogenic group with more than 100 species, infecting humans and fish. The Vibrio spp. is demarcated into two groups, one that causes cholera and the other producing non-cholera or vibriosis infections. People who encounter contaminated water are at risk, but young children and pregnant women are the most vulnerable. Though controllable...
Source: Critical Reviews in Microbiology - June 5, 2023 Category: Microbiology Authors: Brijeshwar Singh Surbhi Jaiswal Prashant Kodgire Source Type: research
Outer membrane proteins and vesicles as promising vaccine candidates against < em > Vibrio < /em > spp. infections
Crit Rev Microbiol. 2023 Jun 5:1-17. doi: 10.1080/1040841X.2023.2212072. Online ahead of print.ABSTRACTIndiscriminate use of antibiotics to treat bacterial infections has brought unmanageable antibiotic-resistant strains into existence. Vibrio spp. represents one such gram-negative enteric pathogenic group with more than 100 species, infecting humans and fish. The Vibrio spp. is demarcated into two groups, one that causes cholera and the other producing non-cholera or vibriosis infections. People who encounter contaminated water are at risk, but young children and pregnant women are the most vulnerable. Though controllable...
Source: Critical Reviews in Microbiology - June 5, 2023 Category: Microbiology Authors: Brijeshwar Singh Surbhi Jaiswal Prashant Kodgire Source Type: research
Outer membrane proteins and vesicles as promising vaccine candidates against < em > Vibrio < /em > spp. infections
Crit Rev Microbiol. 2023 Jun 5:1-17. doi: 10.1080/1040841X.2023.2212072. Online ahead of print.ABSTRACTIndiscriminate use of antibiotics to treat bacterial infections has brought unmanageable antibiotic-resistant strains into existence. Vibrio spp. represents one such gram-negative enteric pathogenic group with more than 100 species, infecting humans and fish. The Vibrio spp. is demarcated into two groups, one that causes cholera and the other producing non-cholera or vibriosis infections. People who encounter contaminated water are at risk, but young children and pregnant women are the most vulnerable. Though controllable...
Source: Critical Reviews in Microbiology - June 5, 2023 Category: Microbiology Authors: Brijeshwar Singh Surbhi Jaiswal Prashant Kodgire Source Type: research
Outer membrane proteins and vesicles as promising vaccine candidates against < em > Vibrio < /em > spp. infections
Crit Rev Microbiol. 2023 Jun 5:1-17. doi: 10.1080/1040841X.2023.2212072. Online ahead of print.ABSTRACTIndiscriminate use of antibiotics to treat bacterial infections has brought unmanageable antibiotic-resistant strains into existence. Vibrio spp. represents one such gram-negative enteric pathogenic group with more than 100 species, infecting humans and fish. The Vibrio spp. is demarcated into two groups, one that causes cholera and the other producing non-cholera or vibriosis infections. People who encounter contaminated water are at risk, but young children and pregnant women are the most vulnerable. Though controllable...
Source: Critical Reviews in Microbiology - June 5, 2023 Category: Microbiology Authors: Brijeshwar Singh Surbhi Jaiswal Prashant Kodgire Source Type: research
Applications of the phage display technology in molecular biology, biotechnology and medicine
Crit Rev Microbiol. 2023 Jun 4:1-41. doi: 10.1080/1040841X.2023.2219741. Online ahead of print.ABSTRACTThe phage display technology is based on the presentation of peptide sequences on the surface of virions of bacteriophages. Its development led to creation of sophisticated systems based on the possibility of the presentation of a huge variability of peptides, attached to one of proteins of bacteriophage capsids. The use of such systems allowed for achieving enormous advantages in the processes of selection of bioactive molecules. In fact, the phage display technology has been employed in numerous fields of biotechnology,...
Source: Critical Reviews in Microbiology - June 4, 2023 Category: Microbiology Authors: Karolina Pierzynowska Joanna Morcinek-Or łowska Lidia Gaffke Weronika Jaroszewicz Piotr M Skowron Grzegorz W ęgrzyn Source Type: research
< em > Acinetobacter baumannii < /em > subunit vaccines: recent progress and challenges
This article provides an updated review of several outer membrane proteins (Omp) that emerged as vaccine candidates with great potential, including OmpA, Omp34, Omp22 and BamA, based on their high conservancy, antigenicity, and immune protection against A. baumannii infection. However, there is still no licenced A. baumannii vaccine currently due to several practical issues that have yet to be resolved, such as inconsistencies between validation studies, antigen variability and insolubility. Moving forward, much investigation and innovation are still required to tackle these challenges for the regulatory approval of an A. ...
Source: Critical Reviews in Microbiology - May 21, 2023 Category: Microbiology Authors: Yi Teng Lau Hock Siew Tan Source Type: research
< em > Acinetobacter baumannii < /em > subunit vaccines: recent progress and challenges
This article provides an updated review of several outer membrane proteins (Omp) that emerged as vaccine candidates with great potential, including OmpA, Omp34, Omp22 and BamA, based on their high conservancy, antigenicity, and immune protection against A. baumannii infection. However, there is still no licenced A. baumannii vaccine currently due to several practical issues that have yet to be resolved, such as inconsistencies between validation studies, antigen variability and insolubility. Moving forward, much investigation and innovation are still required to tackle these challenges for the regulatory approval of an A. ...
Source: Critical Reviews in Microbiology - May 21, 2023 Category: Microbiology Authors: Yi Teng Lau Hock Siew Tan Source Type: research
< em > Acinetobacter baumannii < /em > subunit vaccines: recent progress and challenges
This article provides an updated review of several outer membrane proteins (Omp) that emerged as vaccine candidates with great potential, including OmpA, Omp34, Omp22 and BamA, based on their high conservancy, antigenicity, and immune protection against A. baumannii infection. However, there is still no licenced A. baumannii vaccine currently due to several practical issues that have yet to be resolved, such as inconsistencies between validation studies, antigen variability and insolubility. Moving forward, much investigation and innovation are still required to tackle these challenges for the regulatory approval of an A. ...
Source: Critical Reviews in Microbiology - May 21, 2023 Category: Microbiology Authors: Yi Teng Lau Hock Siew Tan Source Type: research
< em > Acinetobacter baumannii < /em > subunit vaccines: recent progress and challenges
This article provides an updated review of several outer membrane proteins (Omp) that emerged as vaccine candidates with great potential, including OmpA, Omp34, Omp22 and BamA, based on their high conservancy, antigenicity, and immune protection against A. baumannii infection. However, there is still no licenced A. baumannii vaccine currently due to several practical issues that have yet to be resolved, such as inconsistencies between validation studies, antigen variability and insolubility. Moving forward, much investigation and innovation are still required to tackle these challenges for the regulatory approval of an A. ...
Source: Critical Reviews in Microbiology - May 21, 2023 Category: Microbiology Authors: Yi Teng Lau Hock Siew Tan Source Type: research
< em > Acinetobacter baumannii < /em > subunit vaccines: recent progress and challenges
This article provides an updated review of several outer membrane proteins (Omp) that emerged as vaccine candidates with great potential, including OmpA, Omp34, Omp22 and BamA, based on their high conservancy, antigenicity, and immune protection against A. baumannii infection. However, there is still no licenced A. baumannii vaccine currently due to several practical issues that have yet to be resolved, such as inconsistencies between validation studies, antigen variability and insolubility. Moving forward, much investigation and innovation are still required to tackle these challenges for the regulatory approval of an A. ...
Source: Critical Reviews in Microbiology - May 21, 2023 Category: Microbiology Authors: Yi Teng Lau Hock Siew Tan Source Type: research
< em > Acinetobacter baumannii < /em > subunit vaccines: recent progress and challenges
This article provides an updated review of several outer membrane proteins (Omp) that emerged as vaccine candidates with great potential, including OmpA, Omp34, Omp22 and BamA, based on their high conservancy, antigenicity, and immune protection against A. baumannii infection. However, there is still no licenced A. baumannii vaccine currently due to several practical issues that have yet to be resolved, such as inconsistencies between validation studies, antigen variability and insolubility. Moving forward, much investigation and innovation are still required to tackle these challenges for the regulatory approval of an A. ...
Source: Critical Reviews in Microbiology - May 21, 2023 Category: Microbiology Authors: Yi Teng Lau Hock Siew Tan Source Type: research
< em > Acinetobacter baumannii < /em > subunit vaccines: recent progress and challenges
This article provides an updated review of several outer membrane proteins (Omp) that emerged as vaccine candidates with great potential, including OmpA, Omp34, Omp22 and BamA, based on their high conservancy, antigenicity, and immune protection against A. baumannii infection. However, there is still no licenced A. baumannii vaccine currently due to several practical issues that have yet to be resolved, such as inconsistencies between validation studies, antigen variability and insolubility. Moving forward, much investigation and innovation are still required to tackle these challenges for the regulatory approval of an A. ...
Source: Critical Reviews in Microbiology - May 21, 2023 Category: Microbiology Authors: Yi Teng Lau Hock Siew Tan Source Type: research
