The role and challenges of regulating endometrial microbiome in uterine health and diseases
Crit Rev Microbiol. 2024 Mar 15:1-18. doi: 10.1080/1040841X.2024.2320247. Online ahead of print.ABSTRACTThe uterine environment provides necessary conditions for the existence of endometrial microbiota, which in turn plays an important role in maintaining the homeostasis of the uterine environment. The endometrial microbiome is highly susceptible to external factors such as age, hormones, menstrual, pregnancy, etc. When the microbiota is imbalanced, it will further promote the occurrence of uterine diseases such as endometritis and endometrial cancer. Regulating the microbiome of the endometrium is of positive significance...
Source: Critical Reviews in Microbiology - March 15, 2024 Category: Microbiology Authors: Chongshan Yuan Kunyu Xie Lianjun Feng Shouyang Gao Lifu Cai Source Type: research
The role and challenges of regulating endometrial microbiome in uterine health and diseases
Crit Rev Microbiol. 2024 Mar 15:1-18. doi: 10.1080/1040841X.2024.2320247. Online ahead of print.ABSTRACTThe uterine environment provides necessary conditions for the existence of endometrial microbiota, which in turn plays an important role in maintaining the homeostasis of the uterine environment. The endometrial microbiome is highly susceptible to external factors such as age, hormones, menstrual, pregnancy, etc. When the microbiota is imbalanced, it will further promote the occurrence of uterine diseases such as endometritis and endometrial cancer. Regulating the microbiome of the endometrium is of positive significance...
Source: Critical Reviews in Microbiology - March 15, 2024 Category: Microbiology Authors: Chongshan Yuan Kunyu Xie Lianjun Feng Shouyang Gao Lifu Cai Source Type: research
Activation of the lysosomal damage response and selective autophagy: the coordinated actions of galectins, TRIM proteins, and CGAS-STING1 in providing immunity against < em > Mycobacterium tuberculosis < /em >
Crit Rev Microbiol. 2024 Mar 12:1-20. doi: 10.1080/1040841X.2024.2321494. Online ahead of print.ABSTRACTAutophagy is a crucial immune defense mechanism that controls the survival and pathogenesis of M. tb by maintaining cell physiology during stress and pathogen attack. The E3-Ub ligases (PRKN, SMURF1, and NEDD4) and autophagy receptors (SQSTM1, TAX1BP1, CALCOCO2, OPTN, and NBR1) play key roles in this process. Galectins (LGALSs), which bind to sugars and are involved in identifying damaged cell membranes caused by intracellular pathogens such as M. tb, are essential. These include LGALS3, LGALS8, and LGALS9, which respond...
Source: Critical Reviews in Microbiology - March 12, 2024 Category: Microbiology Authors: Asrar Ahmad Malik Mohd Shariq Javaid Ahmad Sheikh Sheeba Zarin Yashika Ahuja Haleema Fayaz Anwar Alam Nasreen Z Ehtesham Seyed E Hasnain Source Type: research
Activation of the lysosomal damage response and selective autophagy: the coordinated actions of galectins, TRIM proteins, and CGAS-STING1 in providing immunity against < em > Mycobacterium tuberculosis < /em >
Crit Rev Microbiol. 2024 Mar 12:1-20. doi: 10.1080/1040841X.2024.2321494. Online ahead of print.ABSTRACTAutophagy is a crucial immune defense mechanism that controls the survival and pathogenesis of M. tb by maintaining cell physiology during stress and pathogen attack. The E3-Ub ligases (PRKN, SMURF1, and NEDD4) and autophagy receptors (SQSTM1, TAX1BP1, CALCOCO2, OPTN, and NBR1) play key roles in this process. Galectins (LGALSs), which bind to sugars and are involved in identifying damaged cell membranes caused by intracellular pathogens such as M. tb, are essential. These include LGALS3, LGALS8, and LGALS9, which respond...
Source: Critical Reviews in Microbiology - March 12, 2024 Category: Microbiology Authors: Asrar Ahmad Malik Mohd Shariq Javaid Ahmad Sheikh Sheeba Zarin Yashika Ahuja Haleema Fayaz Anwar Alam Nasreen Z Ehtesham Seyed E Hasnain Source Type: research
Activation of the lysosomal damage response and selective autophagy: the coordinated actions of galectins, TRIM proteins, and CGAS-STING1 in providing immunity against < em > Mycobacterium tuberculosis < /em >
Crit Rev Microbiol. 2024 Mar 12:1-20. doi: 10.1080/1040841X.2024.2321494. Online ahead of print.ABSTRACTAutophagy is a crucial immune defense mechanism that controls the survival and pathogenesis of M. tb by maintaining cell physiology during stress and pathogen attack. The E3-Ub ligases (PRKN, SMURF1, and NEDD4) and autophagy receptors (SQSTM1, TAX1BP1, CALCOCO2, OPTN, and NBR1) play key roles in this process. Galectins (LGALSs), which bind to sugars and are involved in identifying damaged cell membranes caused by intracellular pathogens such as M. tb, are essential. These include LGALS3, LGALS8, and LGALS9, which respond...
Source: Critical Reviews in Microbiology - March 12, 2024 Category: Microbiology Authors: Asrar Ahmad Malik Mohd Shariq Javaid Ahmad Sheikh Sheeba Zarin Yashika Ahuja Haleema Fayaz Anwar Alam Nasreen Z Ehtesham Seyed E Hasnain Source Type: research
< em > Vibrio cholerae < /em > virulence and its suppression through the quorum-sensing system
Crit Rev Microbiol. 2024 Mar 5:1-22. doi: 10.1080/1040841X.2024.2320823. Online ahead of print.ABSTRACTVibrio cholerae is a cholera-causing pathogen known to instigate severe contagious diarrhea that affects millions globally. Survival of vibrios depend on a combination of multicellular responses and adapt to changes that prevail in the environment. This process is achieved through a strong communication at the cellular level, the process has been recognized as quorum sensing (QS). The severity of infection is highly dependent on the QS of vibrios in the gut milieu. The quorum may exist in a low/high cell density (LCD/HCD)...
Source: Critical Reviews in Microbiology - March 5, 2024 Category: Microbiology Authors: Anusree Sajeevan Thandavarayan Ramamurthy Adline Princy Solomon Source Type: research
< em > Vibrio cholerae < /em > virulence and its suppression through the quorum-sensing system
Crit Rev Microbiol. 2024 Mar 5:1-22. doi: 10.1080/1040841X.2024.2320823. Online ahead of print.ABSTRACTVibrio cholerae is a cholera-causing pathogen known to instigate severe contagious diarrhea that affects millions globally. Survival of vibrios depend on a combination of multicellular responses and adapt to changes that prevail in the environment. This process is achieved through a strong communication at the cellular level, the process has been recognized as quorum sensing (QS). The severity of infection is highly dependent on the QS of vibrios in the gut milieu. The quorum may exist in a low/high cell density (LCD/HCD)...
Source: Critical Reviews in Microbiology - March 5, 2024 Category: Microbiology Authors: Anusree Sajeevan Thandavarayan Ramamurthy Adline Princy Solomon Source Type: research
< em > Vibrio cholerae < /em > virulence and its suppression through the quorum-sensing system
Crit Rev Microbiol. 2024 Mar 5:1-22. doi: 10.1080/1040841X.2024.2320823. Online ahead of print.ABSTRACTVibrio cholerae is a cholera-causing pathogen known to instigate severe contagious diarrhea that affects millions globally. Survival of vibrios depend on a combination of multicellular responses and adapt to changes that prevail in the environment. This process is achieved through a strong communication at the cellular level, the process has been recognized as quorum sensing (QS). The severity of infection is highly dependent on the QS of vibrios in the gut milieu. The quorum may exist in a low/high cell density (LCD/HCD)...
Source: Critical Reviews in Microbiology - March 5, 2024 Category: Microbiology Authors: Anusree Sajeevan Thandavarayan Ramamurthy Adline Princy Solomon Source Type: research
< em > Vibrio cholerae < /em > virulence and its suppression through the quorum-sensing system
Crit Rev Microbiol. 2024 Mar 5:1-22. doi: 10.1080/1040841X.2024.2320823. Online ahead of print.ABSTRACTVibrio cholerae is a cholera-causing pathogen known to instigate severe contagious diarrhea that affects millions globally. Survival of vibrios depend on a combination of multicellular responses and adapt to changes that prevail in the environment. This process is achieved through a strong communication at the cellular level, the process has been recognized as quorum sensing (QS). The severity of infection is highly dependent on the QS of vibrios in the gut milieu. The quorum may exist in a low/high cell density (LCD/HCD)...
Source: Critical Reviews in Microbiology - March 5, 2024 Category: Microbiology Authors: Anusree Sajeevan Thandavarayan Ramamurthy Adline Princy Solomon Source Type: research
< em > Vibrio cholerae < /em > virulence and its suppression through the quorum-sensing system
Crit Rev Microbiol. 2024 Mar 5:1-22. doi: 10.1080/1040841X.2024.2320823. Online ahead of print.ABSTRACTVibrio cholerae is a cholera-causing pathogen known to instigate severe contagious diarrhea that affects millions globally. Survival of vibrios depend on a combination of multicellular responses and adapt to changes that prevail in the environment. This process is achieved through a strong communication at the cellular level, the process has been recognized as quorum sensing (QS). The severity of infection is highly dependent on the QS of vibrios in the gut milieu. The quorum may exist in a low/high cell density (LCD/HCD)...
Source: Critical Reviews in Microbiology - March 5, 2024 Category: Microbiology Authors: Anusree Sajeevan Thandavarayan Ramamurthy Adline Princy Solomon Source Type: research
< em > Vibrio cholerae < /em > virulence and its suppression through the quorum-sensing system
Crit Rev Microbiol. 2024 Mar 5:1-22. doi: 10.1080/1040841X.2024.2320823. Online ahead of print.ABSTRACTVibrio cholerae is a cholera-causing pathogen known to instigate severe contagious diarrhea that affects millions globally. Survival of vibrios depend on a combination of multicellular responses and adapt to changes that prevail in the environment. This process is achieved through a strong communication at the cellular level, the process has been recognized as quorum sensing (QS). The severity of infection is highly dependent on the QS of vibrios in the gut milieu. The quorum may exist in a low/high cell density (LCD/HCD)...
Source: Critical Reviews in Microbiology - March 5, 2024 Category: Microbiology Authors: Anusree Sajeevan Thandavarayan Ramamurthy Adline Princy Solomon Source Type: research
Current developments and prospects of the antibiotic delivery systems
Crit Rev Microbiol. 2024 Feb 29:1-40. doi: 10.1080/1040841X.2024.2321480. Online ahead of print.ABSTRACTAntibiotics have remained the cornerstone for the treatment of bacterial infections ever since their discovery in the twentieth century. The uproar over antibiotic resistance among bacteria arising from genome plasticity and biofilm development has rendered current antibiotic therapies ineffective, urging the development of innovative therapeutic approaches. The development of antibiotic resistance among bacteria has further heightened the clinical failure of antibiotic therapy, which is often linked to its low bioavaila...
Source: Critical Reviews in Microbiology - March 1, 2024 Category: Microbiology Authors: Kusum Kharga Shubhang Jha Tanvi Vishwakarma Lokender Kumar Source Type: research
Current developments and prospects of the antibiotic delivery systems
Crit Rev Microbiol. 2024 Feb 29:1-40. doi: 10.1080/1040841X.2024.2321480. Online ahead of print.ABSTRACTAntibiotics have remained the cornerstone for the treatment of bacterial infections ever since their discovery in the twentieth century. The uproar over antibiotic resistance among bacteria arising from genome plasticity and biofilm development has rendered current antibiotic therapies ineffective, urging the development of innovative therapeutic approaches. The development of antibiotic resistance among bacteria has further heightened the clinical failure of antibiotic therapy, which is often linked to its low bioavaila...
Source: Critical Reviews in Microbiology - March 1, 2024 Category: Microbiology Authors: Kusum Kharga Shubhang Jha Tanvi Vishwakarma Lokender Kumar Source Type: research
Current developments and prospects of the antibiotic delivery systems
Crit Rev Microbiol. 2024 Feb 29:1-40. doi: 10.1080/1040841X.2024.2321480. Online ahead of print.ABSTRACTAntibiotics have remained the cornerstone for the treatment of bacterial infections ever since their discovery in the twentieth century. The uproar over antibiotic resistance among bacteria arising from genome plasticity and biofilm development has rendered current antibiotic therapies ineffective, urging the development of innovative therapeutic approaches. The development of antibiotic resistance among bacteria has further heightened the clinical failure of antibiotic therapy, which is often linked to its low bioavaila...
Source: Critical Reviews in Microbiology - March 1, 2024 Category: Microbiology Authors: Kusum Kharga Shubhang Jha Tanvi Vishwakarma Lokender Kumar Source Type: research
Current developments and prospects of the antibiotic delivery systems
Crit Rev Microbiol. 2024 Feb 29:1-40. doi: 10.1080/1040841X.2024.2321480. Online ahead of print.ABSTRACTAntibiotics have remained the cornerstone for the treatment of bacterial infections ever since their discovery in the twentieth century. The uproar over antibiotic resistance among bacteria arising from genome plasticity and biofilm development has rendered current antibiotic therapies ineffective, urging the development of innovative therapeutic approaches. The development of antibiotic resistance among bacteria has further heightened the clinical failure of antibiotic therapy, which is often linked to its low bioavaila...
Source: Critical Reviews in Microbiology - March 1, 2024 Category: Microbiology Authors: Kusum Kharga Shubhang Jha Tanvi Vishwakarma Lokender Kumar Source Type: research
