Telemedicine in Behavioral Neurology–Neuropsychiatry: Opportunities and Challenges Catalyzed by COVID-19
Coronavirus 2019 (COVID-19) has profoundly impacted the well-being of society and the practice of medicine across health care systems worldwide. As with many other subspecialties, the clinical paradigm in behavioral neurology and neuropsychiatry (BN–NP) was transformed abruptly, transitioning to real-time telemedicine for the assessment and management of the vast majorities of patient populations served by our subspecialty. In this commentary, we outline themes from the BN–NP perspective that reflect the emerging lessons we learned using telemedicine during the COVID-19 pandemic. Positive developments include the abili...
Source: Cognitive and Behavioral Neurology - September 1, 2020 Category: Neurology Tags: Commentary Source Type: research
Relationship Between Cognitive Functions and Insulin-degrading Enzyme in Individuals With Prediabetes
Background:
Individuals with diabetes can develop cognitive impairment due to dysfunction of glucose metabolism; however, it remains unclear whether cognition becomes altered in the prediabetic stage. Substantial evidence links cognitive impairment in diabetes to aberrant serum insulin-degrading enzyme (s[IDE]) levels. This relationship remains to be investigated in individuals with prediabetes.
Objective:
To investigate the relationship between cognitive function and s[IDE] levels in individuals with prediabetes.
Method:
The study group consisted of 47 individuals who had been diagnosed with prediabetes and 41 hea...
Source: Cognitive and Behavioral Neurology - September 1, 2020 Category: Neurology Tags: Original Studies Source Type: research
Mild Cognitive Impairment in Retired Professional Football Players With a History of Mild Traumatic Brain Injury: A Pilot Investigation
Conclusion:
Retired athletes with MCI and a history of mild TBI demonstrated similar neuropsychological profiles as nonathlete controls despite lower scores on measures of confrontation naming and speeded visual attention. These findings suggest that a history of multiple mild TBIs does not significantly alter the overall neuropsychological profile of individuals with MCI; confirmation of this will require longitudinal research with larger sample sizes. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - September 1, 2020 Category: Neurology Tags: Original Studies Source Type: research
Investigations of Memory Monitoring in Individuals With Subjective Cognitive Decline and Amnestic Mild Cognitive Impairment
Background:
Subjective cognitive decline (SCD) has been called the prodromal stage of amnestic mild cognitive impairment (aMCI); however, further investigation is needed to confirm this observation.
Objective:
To define the relationship between SCD and aMCI.
Method:
In this case-control study, we used the feeling-of-knowing in episodic memory (FOK–EM) test to measure the memory-monitoring function of 40 adults with aMCI, 60 with SCD, and 55 healthy controls.
Results:
The recognition rates of FOK–EM (53.53% ± 7.82%; 55.12% ± 6.08%) and judgment accuracy of the aMCI and SCD groups (γ values 0.21 ± 0.11; 0....
Source: Cognitive and Behavioral Neurology - September 1, 2020 Category: Neurology Tags: Original Studies Source Type: research
An Efficient Bedside Measure Yields Prognostic Implications for Language Recovery in Acute Stroke Patients
Conclusion:
The predictive value of this picture description task and correlations with existing language assessments substantiate the clinical importance of a reliable yet rapid bedside measure for acute stroke patients that can be administered by a variety of health care professionals. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - September 1, 2020 Category: Neurology Tags: Original Studies Source Type: research
White Matter Hyperintensities Contribute to Language Deficits in Primary Progressive Aphasia
Conclusion:
Visual ratings of global brain health were associated with language deficits in PPA independent of cortical atrophy and age. While WMH are not unique to PPA, measuring WMH in conjunction with cortical atrophy may elucidate more accurate brain structure–behavior relationships in PPA than cortical atrophy measures alone. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - September 1, 2020 Category: Neurology Tags: Original Studies Source Type: research
The Relationship Between Air Pollution and Cognitive Functions in Children and Adolescents: A Systematic Review
Air pollution has a negative impact on one’s health and on the central nervous system. We decided to assess studies that evaluated the relationship between air pollution and cognitive functions in children and adolescents by reviewing studies that had been published between January 2009 and May 2019. We searched three major databases for original works (26 studies) and for studies using brain imaging methods based on MRI (six studies). Adverse effects of air pollutants on selected cognitive or psychomotor functions were found in all of the studies. Exposure to nitrogen dioxide, for example, was linked to impaired working...
Source: Cognitive and Behavioral Neurology - September 1, 2020 Category: Neurology Tags: Review Source Type: research
Franz Joseph Gall: Naturalist of the Mind, Visionary of the Brain
No abstract available (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - June 1, 2020 Category: Neurology Tags: Book Review Source Type: research
Transcranial Magnetic Stimulation as Treatment for Mal de Debarquement Syndrome: Case Report and Literature Review
This manuscript presents the case of an adult, male patient with mal de debarquement syndrome (MdDS); results from his experimental treatment with repetitive transcranial magnetic stimulation (rTMS) are also provided. Additionally, we included a review of literature related to the neurophysiology of MdDS and its treatment with rTMS. A 41-year-old man had been experiencing symptoms of MdDS, which initially emerged following a car ride, for 11 to 12 years. Pharmacologic approaches had failed to provide symptom relief; thus, we investigated an intervention using low-frequency (1 Hz) rTMS unilaterally for 2 consecutive weeks. ...
Source: Cognitive and Behavioral Neurology - June 1, 2020 Category: Neurology Tags: Case Report Source Type: research
Feeling and Looking Down: Impact of Depressive Symptoms on the Allocation of Vertical Attention
Conclusion:
Depressive symptoms may be associated with a relative lowering of the vertical attentional bias, and this lowering may be related to increased activation of portions of the default network. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - June 1, 2020 Category: Neurology Tags: Original Studies Source Type: research
The Montreal Cognitive Assessment in Veteran Postacute Care: Implications of Cut Scores
Background:
The Montreal Cognitive Assessment (MoCA) is often used for cognitive screening across health care settings, especially in rehabilitation centers, where assessment and treatment of cognitive function is considered key for successful multidisciplinary treatment. Although the original MoCA validation study suggested a cut score of (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - June 1, 2020 Category: Neurology Tags: Original Studies Source Type: research
Clinical Features of Late-onset Semantic Dementia
Background:
Semantic dementia (SD) is characterized by progressive semantic anomia extending to a multimodal loss of semantic knowledge. Although often considered an early-onset dementia, SD also occurs in later life, when it may be misdiagnosed as Alzheimer disease (AD).
Objective:
To evaluate late-onset SD in comparison to early-onset SD and to AD.
Methods:
We identified 74 individuals with SD and then compared those with late-onset SD (≥65 years of age) to those with early-onset SD ( (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - June 1, 2020 Category: Neurology Tags: Original Studies Source Type: research
Cognitive Fatigability is Independent of Subjective Cognitive Fatigue and Mood in Multiple Sclerosis
Background:
Sustained cognitive testing is used to detect cognitive fatigability and is often considered a substitute for subjective cognitive fatigue (CF). However, the relationship between cognitive fatigability and subjective CF in people with multiple sclerosis (PwMS) remains undetermined.
Objective:
To explore potential associations between fatigability induced by sustained cognitive testing and subjective CF in PwMS.
Methods:
We gave 120 PwMS and 60 demographically matched, healthy individuals the Beck Depression Inventory—FastScreen (BDI–FS) to measure mood and the Modified Fatigue Impact Scale to measur...
Source: Cognitive and Behavioral Neurology - June 1, 2020 Category: Neurology Tags: Original Studies Source Type: research
Neurocognitive Impairment in Bipolar Disorder and Associated Factors: Using Population-based Norms and a Strict Criterion for Impairment Definition
Conclusions:
Clinically introducing population norms and a stringent cognitive impairment criterion can facilitate more accurate measures of cognitive impairment in individuals with bipolar disorder. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - June 1, 2020 Category: Neurology Tags: Original Studies Source Type: research
A Scope of the Social Brain in Multiple Sclerosis: Insights From Neuroimaging Studies
Multiple sclerosis (MS) is the most common inflammatory neurologic disease in young adults. Its pathological mechanisms include demyelination, neurodegeneration, and synaptopathy. Cognitive deficits occur in up to 65% of individuals with MS and affect both nonsocial (eg, information processing speed, memory, and executive functions) and social (ie, emotion recognition, theory of mind, and empathy) cognitive domains. In the last 3 decades, there has been a growing interest in social cognition and its relationship with neuropsychological, sociodemographic, and disease characteristics in individuals with MS. Uncovering the ne...
Source: Cognitive and Behavioral Neurology - June 1, 2020 Category: Neurology Tags: Reviews Source Type: research
