An fMRI Study of Differences in Brain Activity Among Elite, Expert, and Novice Archers at the Moment of Optimal Aiming
Conclusions:The more localized neural activity of elite and expert archers than novices permits greater efficiency in the complex processes subserved by these regions. The elite group’s high activity in the cerebellar dentate indicates that the cerebellum is involved in automating simultaneous movements by integrating the sensorimotor memory enabled by greater expertise in self-paced aiming tasks. A companion article comments on and generalizes our findings. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - December 1, 2014 Category: Neurology Tags: Original Study and Invited Commentary Source Type: research

Cerebellar Allocentric and Action-Intentional Spatial Neglect
We describe a patient who had these signs of neglect 7 months after a left cerebellar hemorrhage. This 61-year-old right-handed woman reported emotional lability and difficulty walking, frequently bumping into things on her left side. Neurologic examination revealed ocular dysmetria and left-side limb ataxia. Neuropsychological tests showed evidence of neglect. On a clock-drawing test, the patient accurately drew a circle but her number placement deviated to the left side. She showed the same leftward deviation when she tried to draw a circle composed of small triangles. Although her line bisection was normal, on an alloce...
Source: Cognitive and Behavioral Neurology - September 1, 2014 Category: Neurology Tags: Case Reports Source Type: research

Neuropsychological Function in a Child with 18p Deletion Syndrome: A Case Report
We report the neuropsychological profile of a 4-year-old boy with the rare 18p deletion syndrome. We used a battery of standardized tests to assess his development in intellect, language, visuomotor integration, academic readiness, socialization, and emotional and behavioral health. The results showed borderline intellectual function except for low average nonverbal reasoning skills. He had stronger receptive than expressive language skills, although both were well below his age group. He had impaired visuomotor integration and pre-academic skills such as letter identification. Emotional and behavioral findings indicated m...
Source: Cognitive and Behavioral Neurology - September 1, 2014 Category: Neurology Tags: Case Reports Source Type: research

Progressive Neurodegenerative Syndrome in a Patient with X-Linked Agammaglobulinemia Receiving Intravenous Immunoglobulin Therapy
In this report, we characterize the clinical features of this progressive neurodegenerative dementing disorder in a young man with Bruton agammaglobulinemia, through neuropsychological tests and a video sequence. The clinical course of the encephalopathy seems rather uniform: Cognition, especially frontal lobe function, is affected in the early stages, and some patients develop movement disorders. The syndrome causes severe cognitive and physical disability, and can eventually be fatal. The autoimmunity results from dysregulated immune responses, but the underlying mechanism has not yet been fully explained. (Source: Cogni...
Source: Cognitive and Behavioral Neurology - September 1, 2014 Category: Neurology Tags: Case Reports Source Type: research

Utility of the Montreal Cognitive Assessment and Mini-Mental State Examination in Predicting General Intellectual Abilities
Conclusions:Both the MoCA and MMSE provide reasonable estimates of FSIQ. Prediction improves when these measures are combined with other estimates of FSIQ. We provide 4 equations designed to help clinicians interpret these screening measures. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - September 1, 2014 Category: Neurology Tags: Original Studies Source Type: research

Movement Planning and Online Control in Multiple Sclerosis: Assessment Using a Fitts Law Reciprocal Aiming Task
Conclusions:The computerized Fitts task allows quick, easy, and sensitive measurement of subtle aspects of movement. This task should be useful in clinical and research settings for assessing MS motor symptoms, disease progression, and treatment efficacy. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - September 1, 2014 Category: Neurology Tags: Original Studies Source Type: research

Impaired Visuospatial Transformation but Intact Sequence Processing in Parkinson Disease
Conclusions:We argue that visuospatial deficits in PD result from impairments to spatial transformation routines involved in the computation of mappings between spatial locations. These routines are mediated by dopaminergic pathways linking the basal ganglia, prefrontal cortex, supplementary motor area, and parietal cortex. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - September 1, 2014 Category: Neurology Tags: Original Studies Source Type: research

Feelings Without Memory in Alzheimer Disease
Conclusions:These findings indicate that patients with AD can experience prolonged states of emotion that persist well beyond the patients’ memory for the events that originally caused the emotion. The preserved emotional life evident in patients with AD has important implications for their management and care, and highlights the need for caretakers to foster positive emotional experiences. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - September 1, 2014 Category: Neurology Tags: Original Studies Source Type: research