Non-Alzheimer's and Atypical Dementia
No abstract available (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - December 1, 2016 Category: Neurology Tags: Book Review Source Type: research
Persistent Interictal Musical Hallucination in a Patient With Mesial Temporal Sclerosis-Related Epilepsy: First Case Report and Etiopathological Hypothesis
We describe a 62-year-old woman with a long history of mesial temporal lobe epilepsy whose musical hallucination was solely interictal. We speculate on the possible link between temporal epilepsy and her hallucination. We hypothesize that, as a result of her epileptic activity-induced damage, an imbalance developed between the excitatory and inhibitory projections connecting the mesial temporal cortex to the other auditory structures. These structures may have generated hyperactivity in the lateral temporal cortex through a “release” mechanism that eventually resulted in musical hallucination. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - December 1, 2016 Category: Neurology Tags: Case Reports Source Type: research
Musicogenic Epilepsy and Treatment of Affective Disorders: Case Report and Review of Pathogenesis
Musicogenic epilepsy is a rare syndrome in which music triggers seizures. Affective network processing appears to play a key role in epileptogenesis. Many people with epilepsy suffer from comorbid affective disorders, the shared basis of which involves similar pathophysiologies, including deficiencies of serotonergic and noradrenergic function. Seizures and mood disorders may thus have reciprocal effects on one another, particularly in emotionally precipitated syndromes such as musicogenic epilepsy. I report a man with long-standing depression and anxiety who developed focal epilepsy that evolved into musicogenic seizures....
Source: Cognitive and Behavioral Neurology - December 1, 2016 Category: Neurology Tags: Case Reports Source Type: research
Incidental Learning: A Brief, Valid Measure of Memory Based on the WAIS–IV Vocabulary and Similarities Subtests
Conclusions: Our incidental learning procedures derived from subtests of the WAIS–IV Edition are an efficient and valid way of measuring memory. These tasks add minimally to testing time and capitalize on the semantic encoding that is inherent in completing the Similarities and Vocabulary subtests. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - December 1, 2016 Category: Neurology Tags: Original Studies Source Type: research
Preliminary Predictors of Initial Attendance, Symptom Burden, and Motor Subtype in a US Functional Neurological Disorders Clinic Population
Conclusions: In our FNS cohort, patients were less likely to keep an initial clinic appointment if they were referred from the emergency department than from other sources. Patients with psychogenic non-epileptic seizures were more likely to report cognitive symptoms and past psychiatric hospitalizations than patients with other FNS. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - December 1, 2016 Category: Neurology Tags: Original Studies Source Type: research
Cognition in Patients With a Clinical Diagnosis of Parkinson Disease and Scans Without Evidence of Dopaminergic Deficit (SWEDD): 2-Year Follow-Up
Conclusions: This study provides evidence that some individuals clinically diagnosed with idiopathic Parkinson disease but with SWEDD demonstrate early cognitive decline. The results also suggest that recently diagnosed patients with SWEDD may be at even greater risk for cognitive decline than patients with DaTscan-confirmed early-stage Parkinson disease. While patients with SWEDD likely represent a heterogeneous group of etiologies, our results highlight the need to monitor these patients’ cognitive function over time. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - December 1, 2016 Category: Neurology Tags: Original Studies Source Type: research
Knowns and Unknowns About Delirium in Stroke: A Review
Delirium is a transient condition characterized by sudden and fluctuating disturbances in cognitive function. The condition can be considered a sign of the brain’s vulnerability and diminished resilience to insult. Among the many clinical manifestations are cognitive, psychomotor, and sleep disturbances. Delirium is associated with longer hospital stays, worse functional outcomes, and higher mortality. Although up to 48% of patients who have had a stroke develop delirium, the condition has been studied much less in these patients than in general medicine, surgical, and intensive care patients. Coexisting neurologic defic...
Source: Cognitive and Behavioral Neurology - December 1, 2016 Category: Neurology Tags: Review Article Source Type: research
Considerations in Writing About Single-Case Experimental Design Studies
Single-case experimental design (SCED) studies are particularly useful for examining the processes and outcomes of psychological and behavioral studies. Accurate reporting of SCED studies is critical in explaining the study to the reader and allowing replication. This paper outlines important elements that authors should cover when reporting the results of a SCED study. Authors should provide details on the participant, independent and dependent variables under examination, materials and procedures, and data analysis. Particular emphasis should be placed on justifying the assumptions made and explaining how violations of t...
Source: Cognitive and Behavioral Neurology - December 1, 2016 Category: Neurology Tags: Position Paper Source Type: research
Literature, Neurology, and Neuroscience: Neurological and Psychiatric Disorders
No abstract available (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - September 1, 2016 Category: Neurology Tags: Book Review Source Type: research
Left Dorsomedial Thalamic Damage Impairs Verbal Recall More Than Recognition: A Case Report
Damage to the dorsomedial thalamus usually leads to impaired episodic memory, attention, and executive function, but the role of the dorsomedial thalamus in memory processing is still not fully understood. Clinical evidence is inconclusive about whether dorsomedial thalamic damage impairs recall or whether it impairs recognition. I report a unique patient who suffered a cardioembolic stroke in the paramedian artery territory, caused by a patent foramen ovale. He was left with a chronic ischemic lesion centered in the parvocellular and, to a lesser extent, the magnocellular portions of the left dorsomedial thalamic nucleus,...
Source: Cognitive and Behavioral Neurology - September 1, 2016 Category: Neurology Tags: Case Reports Source Type: research
A Case of Reduplicative Paramnesia for Home
We describe the patient in detail and link to a video interview of her 3 months after the onset of the delusion, eloquently describing her experience. We summarize some of the many reports and discussions of our patient’s delusion, reduplicative paramnesia, as well as other delusional misidentification syndromes. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - September 1, 2016 Category: Neurology Tags: Case Reports Source Type: research
Elevated Cystatin C Levels Are Associated with Cognitive Impairment and Progression of Parkinson Disease
Objective: We investigated the relationship between serum cystatin C (CysC) levels and cognitive dysfunction and disease progression in patients with Parkinson disease.
Background: Previous studies have reported altered CysC levels in neurodegenerative disorders, but only a few studies have explored the role of CysC and its relationship to cognitive dysfunction in Parkinson disease.
Methods: We measured serum levels of CysC, creatinine, urea, and uric acid in 142 patients with Parkinson disease and 146 healthy controls. We assessed disease progression using the Hoehn and Yahr scale, and cognitive function using the Montr...
Source: Cognitive and Behavioral Neurology - September 1, 2016 Category: Neurology Tags: Original Studies Source Type: research
Basal Ganglia Calcification in Psychiatric Inpatients: A Case-Control Study
Conclusions: Patients with BGC tend to develop psychiatric symptoms later in life than other psychiatric patients, and have higher rates of medical comorbidities. Many patients with BGC have cognitive symptoms, which can be concurrent with a mood or psychotic disorder. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - September 1, 2016 Category: Neurology Tags: Original Studies Source Type: research
Effects of Testosterone Therapy on Cognitive Function in Aging: A Systematic Review
Endogenous testosterone in the aging man has been scrutinized extensively in regard to its effects on performance in many cognitive domains, especially verbal fluency, visuospatial and visuoperceptual abilities, memory, and executive function. Studies of testosterone supplementation have sought to identify potential cognitive improvements in men with and without baseline cognitive impairment, and have had a wide range of results. The variability in outcomes is likely related, in part, to the lack of consensus on methods for testosterone measurement and supplementation and, in part, to the disparate measures of cognitive fu...
Source: Cognitive and Behavioral Neurology - September 1, 2016 Category: Neurology Tags: Topical Review Source Type: research
tDCS Effects on Verbal Fluency: A Response to Vannorsdall et al (2016)
In a prior study (Cattaneo et al, 2011. Neuroscience. 183:64–70), we demonstrated that anodal transcranial direct current stimulation (tDCS) over the left inferior frontal gyrus enhanced verbal fluency in healthy young adults. Although our data are in line with the results of other published studies, another research group recently failed to report anodal tDCS effects on verbal fluency using a paradigm similar to ours (Vannorsdall et al, 2016. Cogn Behav Neurol. 29:11–17). Here we discuss aspects of study design and interpretation of results that should be considered in replications, focusing particularly on homogeneit...
Source: Cognitive and Behavioral Neurology - September 1, 2016 Category: Neurology Tags: Commentary Source Type: research
