The Swimmers: A Novel
No abstract available (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - September 1, 2022 Category: Neurology Tags: Book Review Source Type: research
Phenotypic and Brain Imaging Findings Associated With a 10p Proximal Deletion Including the WAC Gene: Case Report and Literature Review
Microarray-based techniques are an important testing method in etiological studies of intellectual disability and autism spectrum disorder. Interstitial deletion in the p11–p12 region of chromosome 10 is rare, having been reported in just 12 cases to date. Intellectual disability associated with the WAC gene in this region is referred to as DeSanto-Shinawi syndrome. Although all individuals with p11–p12 region of chromosome 10 deletion share a common phenotype involving intellectual disability and dysmorphic features, individuals with DeSanto-Shinawi syndrome usually do not experience the cardiac and neurologic abnorma...
Source: Cognitive and Behavioral Neurology - September 1, 2022 Category: Neurology Tags: Case Reports Source Type: research
Nonparaneoplastic Anti-GAD Limbic Encephalitis: Seizure Outcome and Long-term Neuropsychological Follow-up After Immunotherapy
We present the case of a 42-year-old Greek woman with nonparaneoplastic anti-GAD LE, discussing the therapeutic management and highlighting the role of neuropsychological assessment. The patient underwent functional and structural brain studies and was investigated longitudinally over a 6-year period with a battery of neuropsychological tests that were designed to document her intellectual function and verbal and visual memory. The patient suffered from refractory temporal-impaired awareness seizures and memory impairment that was mediated by autoimmune nonparaneoplastic LE and comorbid autoimmune disorders (ie, Hashimoto ...
Source: Cognitive and Behavioral Neurology - September 1, 2022 Category: Neurology Tags: Case Reports Source Type: research
Executive Dysfunction, Social Cognition Impairment, and Gray Matter Pathology in Myotonic Dystrophy Type 2: A Pilot Study
Conclusion:
DM2 may be associated with multifocal cortical and thalamic atrophy, which is likely to underpin the range of cognitive manifestations mostly characterized by executive impairment and specifically by impaired social cognition. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - September 1, 2022 Category: Neurology Tags: Original Studies Source Type: research
The Repeatable Battery for the Assessment of Neuropsychological Status, While Useful for Measuring Cognitive Changes in Manifest Huntington Disease, May Show Limited Utility in Premanifest Disease
Conclusion:
Our results substantiate previous findings of significant impairment on the RBANS in individuals with HD. In addition, we are the first to demonstrate that, although the RBANS can identify deficits in psychomotor speed and information processing in individuals with PreHD, it does not appear to have the ability to detect impairment in any additional cognitive domains in individuals with PreHD. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - September 1, 2022 Category: Neurology Tags: Original Studies Source Type: research
Distinguishing Between Genuine and Feigned Dementia Using Event-related Potentials
Conclusion:
The P3b peak amplitude was found to be an effective physiologic measure of cognitive impairment in individuals with probable AD compared with HC simulating dementia. When combined with the TOMM Trial 2 score, the P3b peak amplitude served as a promising performance validity measure for differentiating individuals with probable AD from HC simulating dementia. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - September 1, 2022 Category: Neurology Tags: Original Studies Source Type: research
Graph Theory Analysis of Semantic Fluency in Russian–English Bilinguals
Conclusion:
The networks had similar graph theory properties in both languages. The optimal methodology for creating networks from semantic category fluency remains to be determined. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - September 1, 2022 Category: Neurology Tags: Original Studies Source Type: research
Validation of a Mobile, Sensor-based Neurobehavioral Assessment With Digital Signal Processing and Machine-learning Analytics
Conclusion:
The Miro Health Mobile Assessment Platform provides valid and reliable assessment of neurobehavioral and cognitive status, effectively distinguishes between HC and MCI, and differentiates aMCI from naMCI. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - September 1, 2022 Category: Neurology Tags: Original Studies Source Type: research
BNT–15: Revised Performance Validity Cutoffs and Proposed Clinical Classification Ranges
Conclusion:
Given its brevity ( (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - September 1, 2022 Category: Neurology Tags: Original Studies Source Type: research
The Mental Status Examination Handbook
No abstract available (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - June 1, 2022 Category: Neurology Tags: Book Review Source Type: research
White Matter, Behavioral Neurology, and the Influence of Corticocentrism
White matter in the human brain occupies roughly the same volume as gray matter but has received far less attention in behavioral neurology and related disciplines. In particular, the cerebral cortex has long dominated thinking about the organization of brain–behavior relationships. As a result, subcortical structures, including deep gray matter and, most notably, white matter, have been accorded relatively little neuroscientific study compared with the extensive work devoted to the cerebral cortex. The influence of corticocentrism can be explained by several factors, including historical precedent in neurology strongly ...
Source: Cognitive and Behavioral Neurology - June 1, 2022 Category: Neurology Tags: Commentary Source Type: research
Neurosyphilis Mimicking Behavioral Variant of Frontotemporal Dementia in a 59-Year-Old Man
We present the case of a man exhibiting a clinical phenotype of behavioral variant of frontotemporal dementia (bvFTD). The man had developed psychiatric disturbances with verbal aggressiveness over a few months, followed by cognitive and frontal behavioral disorders, fulfilling the clinical criteria for bvFTD. Atrophy and hypometabolism in frontotemporal regions were consistent with the diagnosis. However, serum-screening exams for syphilis infection were positive, and CSF analysis, despite a negative Venereal Disease Research Laboratory Test, suggested the diagnosis of neurosyphilis. After specific antibiotic therapy, the...
Source: Cognitive and Behavioral Neurology - June 1, 2022 Category: Neurology Tags: Case Report Source Type: research
Changes in Cognitive Functioning After Surgical Resection of Language-related, Eloquent-area, High-grade Gliomas Under Awake Craniotomy
Background:
Dominant-hemisphere tumors, especially gliomas, as infiltrative tumors, frequently affect cognitive functioning. Establishing a balance between extensive resection, which is proven to result in longer survival, and less extensive resection, in order to maintain more cognitive abilities, is challenging.
Objective:
To evaluate changes in cognitive functioning before and after surgical resection of language-related, eloquent-area, high-grade gliomas under awake craniotomy.
Method:
We provided individuals with newly diagnosed high-grade gliomas of the language-related eloquent areas with the same ...
Source: Cognitive and Behavioral Neurology - June 1, 2022 Category: Neurology Tags: Original Studies Source Type: research
Delirium as a Presenting Symptom of COVID–19
Conclusion:
Our results are largely consistent with prior studies and suggest that delirium is a common, early occurring, and lethal manifestation of COVID–19 in older adults presenting to the ED, in most cases causing acute on chronic neurocognitive dysfunction strongly influenced by inflammatory and hypoxic–ischemic mechanisms. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - June 1, 2022 Category: Neurology Tags: Original Studies Source Type: research
Disentangling Reversal-learning Impairments in Frontotemporal Dementia and Alzheimer Disease
Conclusion:
Taken together, these results and the reversal-learning paradigm used in this study may inform the development and screening of behavioral, neurostimulatory, or pharmacologic interventions aiming to address behavioral symptoms related to stimulus-reinforcement learning and response inhibition impairments in individuals with FTD. (Source: Cognitive and Behavioral Neurology)
Source: Cognitive and Behavioral Neurology - June 1, 2022 Category: Neurology Tags: Original Studies Source Type: research
