British Royalty and Aristocracy: Their skin maladies Part I. Winston Churchill: Wartime skin graft donor
Following the 1898 Battle of Omdurman in Sudan, Winston Churchill, then a second lieutenant in the British army, donated a skin graft to Richard Molyneux, a wounded fellow officer. This contribution tells the story of Churchill's skin graft donation within the context of the development of skin grafting as a viable treatment for serious wounds and burns. (Source: Clinics in Dermatology)
Source: Clinics in Dermatology - July 27, 2022 Category: Dermatology Authors: Devinder Singh, Nick J. Levell, Lawrence Charles Parish, Leonard J. Hoenig Source Type: research

British Royalty and Aristocracy: Their Skin Maladies Part I: Winston Churchill: Wartime Skin Graft Donor
Following the 1898 Battle of Omdurman, Sudan, Winston Churchill, then a Second Lieutenant in the British army, donated a skin graft to Richard Molyneux, a wounded fellow officer. This contribution tells the story of Churchill's skin graft donation within the context of the development of skin grafting as a viable treatment for serious wounds and burns. (Source: Clinics in Dermatology)
Source: Clinics in Dermatology - July 27, 2022 Category: Dermatology Authors: Devinder Singh, Nick Levell, Lawrence Charles Parish, Leonard J. Hoenig Source Type: research

Localized Lymphomatoid Papulosis: Unilesional Lymphomatoid Papulosis, Regional Lymphomatoid Papulosis, And Persistent Agminated Lymphomatoid Papulosis
Lymphomatoid papulosis (LYP), the most common primary cutaneous CD30-positive lymphoproliferative disorder, is heralded by multiple papular and nodular lesions at anatomically discontiguous cutaneous sites. The histologic patterns are protean. A very uncommon form of LYP is one that is anatomically confined. Cases of unilesional lymphomatoid papulosis, regional lymphomatoid papulosis and persistent agmination of lymphomatoid papulosis were encountered in the routine and consultative practices of Weill Cornell Medicine, Division of Dermatopathology. (Source: Clinics in Dermatology)
Source: Clinics in Dermatology - July 27, 2022 Category: Dermatology Authors: Cynthia M. Magro, Joshua H. Mo, Gladys Telang Source Type: research

Leukocytoclastic Vasculitis in Association with Linear Epidermal Basement Membrane Zone Immunoglobulin Deposition: Linear Vasculitis
Leukocytoclastic vasculitis has a distinctive clinical and light microscopic presentation; however, the etiologic basis of leukocytoclastic vasculitis is varied. The majority of cases are attributable to immune complex deposition within a vessel wall and represent an Arthus type III immune complex reaction. The prototypic immunoreactant profile is characterized by granular deposits of components of complement activation in concert with immunoglobulin within the cutaneous vasculature. We encountered nine patients with protean skin rashes including those clinically consistent with vesiculobullous eruptions that showed a leuk...
Source: Clinics in Dermatology - July 27, 2022 Category: Dermatology Authors: Cynthia M. Magro, Joshua H. Mo, Mary Jo Kearns Source Type: research

Birt-Hogg-Dub é Syndrome: Another mTOR Phenomenon
Birt-Hogg-Dub é syndrome is an uncommon autosomal dominant systemic disorder with cutaneous findings notable for fibrofolliculomas or trichodiscomas on the scalp, face, neck, and trunk. These cutaneous signs are associated with bilateral renal cell carcinoma, benign renal cysts, pulmonary cysts, and spontaneous pneumothorax. Given its autosomal dominant inheritance pattern, the successful diagnosis of BHDS may elucidate a diagnosis in family members. BHDS results from a mutation in the FLCN gene encoding the folliculin protein, a transcriptional regulator of the mammalian target of rapamycin (mTOR) signali ng pathway. (So...
Source: Clinics in Dermatology - July 27, 2022 Category: Dermatology Authors: Rohan R. Shah, W. Clark Lambert, Robert A. Schwartz Source Type: research

History of Leprosy in India: An overview of historic and modern contributions
Traditionally, India holds the unenviable position of the origin of leprosy. The disease is thought to have spread, via trade and war, to China, Egypt, and the Middle East, and later to Europe and the Americas. From antiquity to modernity, Indian society treated leprosy singularly for custom and law, a response shaped by both scientific knowledge and cultural attitudes. Over the past centuries, tireless research by eminent physicians and scientists working in India. like Carter, Rogers, Muir, Dharmendra, Khanolkar, and Bapat, amongst others, have led to a better understanding of clinical, bacteriologic, pathologic, and imm...
Source: Clinics in Dermatology - July 27, 2022 Category: Dermatology Authors: Abheek Sil, Anupam Das Source Type: research

Subacute cutaneous lupus erythematosus: A facultative paraneoplastic dermatosis
Subacute cutaneous lupus erythematosus (SCLE) is a photosensitive dermatosis characterized by a non-scarring papulosquamous eruption and specific antibodies in the patient's serum. Genetic and environmental factors represent the leading causes of SCLE; however, several case reports in the literature link SCLE to various types of cancer. This review aims to assess the association between SCLE and neoplastic disorders. We searched PubMed for all relevant publications on cancer-associated SCLE from 1981 to 2022. (Source: Clinics in Dermatology)
Source: Clinics in Dermatology - July 27, 2022 Category: Dermatology Authors: Andrada-Luciana Lazar Source Type: research

Side effects of gel nail polish: a systematic review
Gel nail polish (GNP) has recently gained worldwide popularity. We have conducted a comprehensive summary of the complications of GNP through a literature search using PubMed, Scopus, and Google Scholar databases to identify eligible papers. Complications were divided into mechanical and traumatic nail disorders, allergic contact dermatitis (ACD), and UV-induced lesions. A total of 12 contributions were included, identifying 88 patients, all of whom were women. Six of the reports described ACD (62 cases, 70,5%), three concerned mechanical nail damage (23 cases, 26,1%), and three reported UV-induced skin lesions (3 cases, 3...
Source: Clinics in Dermatology - July 27, 2022 Category: Dermatology Authors: Noureddine Litaiem, Massara Baklouti, Faten Zeglaoui Source Type: research

Melanotic lupus erythematosus: a review of a newly described clinical form of chronic cutaneous lupus erythematosus
Melanotic lupus erythematosus (LE), is a rare and newly described form of chronic cutaneous lupus erythematosus (CLE). In this review, we have synthesizee existing data on the epidemiologic, clinical, histologic, and immunologic features of melanotic LE. We performed a systematic review using PubMed to identify eligible publications Eight papers fulfilled the eligibility criteria and were included in the qualitative synthesis. Twenty-eight patients with a mean age of 57.7 years, were included. All patients had medium to dark skin phototypes. (Source: Clinics in Dermatology)
Source: Clinics in Dermatology - July 27, 2022 Category: Dermatology Authors: Noureddine Litaiem, Meriem Rouai, Maroua Slouma, Soumaya Rammeh, Faten Zeglaoui Source Type: research

The challenge of Morgellons disease: A patient with clinicopathologic correlation
Morgellons disease is a rare condition characterized by patient-reported multicolored fibers and other nonorganic particles or organic particles embedded in and protruding from diffuse skin ulcerations. Although the scientific community is prone to believe that Morgellons disease is a psychiatric disorder, an infectious pathogenesis associated with Borrelia burgdorferi in the setting of Lyme disease has also been proposed. The histopathology is usually considered as nonspecific. To illustrate this condition, we present the case of an adult woman with significant ulcerative skin lesions and cicatricial changes on the face, ...
Source: Clinics in Dermatology - July 26, 2022 Category: Dermatology Authors: Valentina Caputo, Emanuela Bonoldi, Antonella Citterio, Franco Rongioletti Source Type: research

The challenge of Morgellons disease: a patient with clinico-pathologic correlation
Morgellons disease is a rare condition characterized by patient reporting multicolored fibers and other non-organic or organic particles embedded in and protruding from diffuse skin ulcerations. Although the scientific community is prone to believe that Morgellons disease is a psychiatric disorder, an infectious pathogenesis associated with Borrelia burgdorferi in the setting of Lyme disease has also been proposed. The histopathology is usually considered as non-specific. To illustrate this condition, we present the case of an adult woman with significant ulcerative skin lesions and cicatricial changes on the face, trunk, ...
Source: Clinics in Dermatology - July 26, 2022 Category: Dermatology Authors: Valentina Caputo, Emanuela Bonoldi, Antonella Citterio, Franco Rongioletti Source Type: research

Cover 2 - Editorial Board with barcode
(Source: Clinics in Dermatology)
Source: Clinics in Dermatology - July 1, 2022 Category: Dermatology Source Type: research

Table of Contents
(Source: Clinics in Dermatology)
Source: Clinics in Dermatology - July 1, 2022 Category: Dermatology Source Type: research

The Dermatologist Who Studied Music under Aaron Copland: John Thorne Crissey, MD
John Crissey was a master teacher of dermatology and its history. He also enjoyed composing music. In 1958, Crissey received the thrill of a lifetime: the opportunity to study advanced musical composition under the tutelage of Aaron Copland, “the Dean of American Composers.” This contribution tells the story of that didactic experience. It also pays tribute to two remarkable men, who contributed so much to the development of their respective professions and whose music has enriched the world with its beauty. (Source: Clinics in Dermatology)
Source: Clinics in Dermatology - June 1, 2022 Category: Dermatology Authors: By Leonard J. Hoenig, Lawrence Charles Parish Tags: Correspondence Source Type: research

Teenage dating abuse, rape, and violence: The dermatologist's role
Teenage dating abuse, rape, and violence are considered major public health problems that affect the lives of millions of teenagers in the United States. Dermatologists have traditionally become involved in these cases when confronted with patients who have unexplained bruising or other skin injuries and/or sexually transmitted diseases that raise the possibility that they could be victims of sexual abuse and violence. This contribution explores the role of the dermatologist in the diagnosis and management of teen dating abuse. (Source: Clinics in Dermatology)
Source: Clinics in Dermatology - May 30, 2022 Category: Dermatology Authors: Matthew Van Leer-Greenberg, Laura C. Hudson, Leonard J. Hoenig Tags: Reflections on Dermatology: Past, Present, and Future Source Type: research