Chiral recognition mechanism studies of Tyr-Arg-Phe-Lys-NH < sub > 2 < /sub > tetrapeptide on crown ether-based chiral stationary phase
Chirality. 2023 Sep 12. doi: 10.1002/chir.23619. Online ahead of print.ABSTRACTEven though chiral recognition for crown-ether CSPs is generally understood, on a molecular level, exact mechanisms for the resolution are still unclear. Furthermore, short peptide analytes often contain multiple amino moieties capable of binding to the crown ether selector. In order to extend the understanding in chiral recognition mechanisms, polar organic mode separation of Tyr-Arg-Phe-Lys-NH2 tetrapeptide llll/dddd enantiomers on S- and R-(3,3'-diphenyl-1,1'-binaphthyl)-20-crown-6 stationary phases was studied with 50-mM perchloric acid in m...
Source: Chirality - September 13, 2023 Category: Molecular Biology Authors: Toms Upmanis Eduards Sevostjanovs Helena Ka žoka Source Type: research
Achiral 2-pyridone and 4-aminopyridine act as chiral inducers of asymmetric autocatalysis with amplification of enantiomeric excess via the formation of chiral crystals
Chirality. 2023 Aug 24. doi: 10.1002/chir.23617. Online ahead of print.ABSTRACTEnantiomorphous crystals of achiral 2-pyridone and 4-aminopyridine served as sources of chirality, to induce the asymmetric autocatalysis of 5-pyrimidyl alkanol during the asymmetric addition of diisopropylzinc to the corresponding pyrimidine-5-carbaldehyde, that is, the Soai reaction. Following a significant amplification of enantiomeric excess through asymmetric autocatalysis, highly enantioenriched 5-pyrimidyl alkanol could be synthesized with their corresponding absolute configurations to those of chiral crystals of 2-pyridone and 4-aminopyr...
Source: Chirality - August 25, 2023 Category: Molecular Biology Authors: Arimasa Matsumoto Daisuke Tateishi Tsuyoshi Nakajima Shiori Kurosaki Tomohiro Ogawa Tsuneomi Kawasaki Kenso Soai Source Type: research
Achiral 2-pyridone and 4-aminopyridine act as chiral inducers of asymmetric autocatalysis with amplification of enantiomeric excess via the formation of chiral crystals
Chirality. 2023 Aug 24. doi: 10.1002/chir.23617. Online ahead of print.ABSTRACTEnantiomorphous crystals of achiral 2-pyridone and 4-aminopyridine served as sources of chirality, to induce the asymmetric autocatalysis of 5-pyrimidyl alkanol during the asymmetric addition of diisopropylzinc to the corresponding pyrimidine-5-carbaldehyde, that is, the Soai reaction. Following a significant amplification of enantiomeric excess through asymmetric autocatalysis, highly enantioenriched 5-pyrimidyl alkanol could be synthesized with their corresponding absolute configurations to those of chiral crystals of 2-pyridone and 4-aminopyr...
Source: Chirality - August 25, 2023 Category: Molecular Biology Authors: Arimasa Matsumoto Daisuke Tateishi Tsuyoshi Nakajima Shiori Kurosaki Tomohiro Ogawa Tsuneomi Kawasaki Kenso Soai Source Type: research
Achiral 2-pyridone and 4-aminopyridine act as chiral inducers of asymmetric autocatalysis with amplification of enantiomeric excess via the formation of chiral crystals
Chirality. 2023 Aug 24. doi: 10.1002/chir.23617. Online ahead of print.ABSTRACTEnantiomorphous crystals of achiral 2-pyridone and 4-aminopyridine served as sources of chirality, to induce the asymmetric autocatalysis of 5-pyrimidyl alkanol during the asymmetric addition of diisopropylzinc to the corresponding pyrimidine-5-carbaldehyde, that is, the Soai reaction. Following a significant amplification of enantiomeric excess through asymmetric autocatalysis, highly enantioenriched 5-pyrimidyl alkanol could be synthesized with their corresponding absolute configurations to those of chiral crystals of 2-pyridone and 4-aminopyr...
Source: Chirality - August 25, 2023 Category: Molecular Biology Authors: Arimasa Matsumoto Daisuke Tateishi Tsuyoshi Nakajima Shiori Kurosaki Tomohiro Ogawa Tsuneomi Kawasaki Kenso Soai Source Type: research
Achiral 2-pyridone and 4-aminopyridine act as chiral inducers of asymmetric autocatalysis with amplification of enantiomeric excess via the formation of chiral crystals
Chirality. 2023 Aug 24. doi: 10.1002/chir.23617. Online ahead of print.ABSTRACTEnantiomorphous crystals of achiral 2-pyridone and 4-aminopyridine served as sources of chirality, to induce the asymmetric autocatalysis of 5-pyrimidyl alkanol during the asymmetric addition of diisopropylzinc to the corresponding pyrimidine-5-carbaldehyde, that is, the Soai reaction. Following a significant amplification of enantiomeric excess through asymmetric autocatalysis, highly enantioenriched 5-pyrimidyl alkanol could be synthesized with their corresponding absolute configurations to those of chiral crystals of 2-pyridone and 4-aminopyr...
Source: Chirality - August 25, 2023 Category: Molecular Biology Authors: Arimasa Matsumoto Daisuke Tateishi Tsuyoshi Nakajima Shiori Kurosaki Tomohiro Ogawa Tsuneomi Kawasaki Kenso Soai Source Type: research
Achiral 2-pyridone and 4-aminopyridine act as chiral inducers of asymmetric autocatalysis with amplification of enantiomeric excess via the formation of chiral crystals
Chirality. 2023 Aug 24. doi: 10.1002/chir.23617. Online ahead of print.ABSTRACTEnantiomorphous crystals of achiral 2-pyridone and 4-aminopyridine served as sources of chirality, to induce the asymmetric autocatalysis of 5-pyrimidyl alkanol during the asymmetric addition of diisopropylzinc to the corresponding pyrimidine-5-carbaldehyde, that is, the Soai reaction. Following a significant amplification of enantiomeric excess through asymmetric autocatalysis, highly enantioenriched 5-pyrimidyl alkanol could be synthesized with their corresponding absolute configurations to those of chiral crystals of 2-pyridone and 4-aminopyr...
Source: Chirality - August 25, 2023 Category: Molecular Biology Authors: Arimasa Matsumoto Daisuke Tateishi Tsuyoshi Nakajima Shiori Kurosaki Tomohiro Ogawa Tsuneomi Kawasaki Kenso Soai Source Type: research
Achiral 2-pyridone and 4-aminopyridine act as chiral inducers of asymmetric autocatalysis with amplification of enantiomeric excess via the formation of chiral crystals
Chirality. 2023 Aug 24. doi: 10.1002/chir.23617. Online ahead of print.ABSTRACTEnantiomorphous crystals of achiral 2-pyridone and 4-aminopyridine served as sources of chirality, to induce the asymmetric autocatalysis of 5-pyrimidyl alkanol during the asymmetric addition of diisopropylzinc to the corresponding pyrimidine-5-carbaldehyde, that is, the Soai reaction. Following a significant amplification of enantiomeric excess through asymmetric autocatalysis, highly enantioenriched 5-pyrimidyl alkanol could be synthesized with their corresponding absolute configurations to those of chiral crystals of 2-pyridone and 4-aminopyr...
Source: Chirality - August 25, 2023 Category: Molecular Biology Authors: Arimasa Matsumoto Daisuke Tateishi Tsuyoshi Nakajima Shiori Kurosaki Tomohiro Ogawa Tsuneomi Kawasaki Kenso Soai Source Type: research
Achiral 2-pyridone and 4-aminopyridine act as chiral inducers of asymmetric autocatalysis with amplification of enantiomeric excess via the formation of chiral crystals
Chirality. 2023 Aug 24. doi: 10.1002/chir.23617. Online ahead of print.ABSTRACTEnantiomorphous crystals of achiral 2-pyridone and 4-aminopyridine served as sources of chirality, to induce the asymmetric autocatalysis of 5-pyrimidyl alkanol during the asymmetric addition of diisopropylzinc to the corresponding pyrimidine-5-carbaldehyde, that is, the Soai reaction. Following a significant amplification of enantiomeric excess through asymmetric autocatalysis, highly enantioenriched 5-pyrimidyl alkanol could be synthesized with their corresponding absolute configurations to those of chiral crystals of 2-pyridone and 4-aminopyr...
Source: Chirality - August 25, 2023 Category: Molecular Biology Authors: Arimasa Matsumoto Daisuke Tateishi Tsuyoshi Nakajima Shiori Kurosaki Tomohiro Ogawa Tsuneomi Kawasaki Kenso Soai Source Type: research
Achiral 2-pyridone and 4-aminopyridine act as chiral inducers of asymmetric autocatalysis with amplification of enantiomeric excess via the formation of chiral crystals
Chirality. 2023 Aug 24. doi: 10.1002/chir.23617. Online ahead of print.ABSTRACTEnantiomorphous crystals of achiral 2-pyridone and 4-aminopyridine served as sources of chirality, to induce the asymmetric autocatalysis of 5-pyrimidyl alkanol during the asymmetric addition of diisopropylzinc to the corresponding pyrimidine-5-carbaldehyde, that is, the Soai reaction. Following a significant amplification of enantiomeric excess through asymmetric autocatalysis, highly enantioenriched 5-pyrimidyl alkanol could be synthesized with their corresponding absolute configurations to those of chiral crystals of 2-pyridone and 4-aminopyr...
Source: Chirality - August 25, 2023 Category: Molecular Biology Authors: Arimasa Matsumoto Daisuke Tateishi Tsuyoshi Nakajima Shiori Kurosaki Tomohiro Ogawa Tsuneomi Kawasaki Kenso Soai Source Type: research
Achiral 2-pyridone and 4-aminopyridine act as chiral inducers of asymmetric autocatalysis with amplification of enantiomeric excess via the formation of chiral crystals
Chirality. 2023 Aug 24. doi: 10.1002/chir.23617. Online ahead of print.ABSTRACTEnantiomorphous crystals of achiral 2-pyridone and 4-aminopyridine served as sources of chirality, to induce the asymmetric autocatalysis of 5-pyrimidyl alkanol during the asymmetric addition of diisopropylzinc to the corresponding pyrimidine-5-carbaldehyde, that is, the Soai reaction. Following a significant amplification of enantiomeric excess through asymmetric autocatalysis, highly enantioenriched 5-pyrimidyl alkanol could be synthesized with their corresponding absolute configurations to those of chiral crystals of 2-pyridone and 4-aminopyr...
Source: Chirality - August 25, 2023 Category: Molecular Biology Authors: Arimasa Matsumoto Daisuke Tateishi Tsuyoshi Nakajima Shiori Kurosaki Tomohiro Ogawa Tsuneomi Kawasaki Kenso Soai Source Type: research
Achiral 2-pyridone and 4-aminopyridine act as chiral inducers of asymmetric autocatalysis with amplification of enantiomeric excess via the formation of chiral crystals
Chirality. 2023 Aug 24. doi: 10.1002/chir.23617. Online ahead of print.ABSTRACTEnantiomorphous crystals of achiral 2-pyridone and 4-aminopyridine served as sources of chirality, to induce the asymmetric autocatalysis of 5-pyrimidyl alkanol during the asymmetric addition of diisopropylzinc to the corresponding pyrimidine-5-carbaldehyde, that is, the Soai reaction. Following a significant amplification of enantiomeric excess through asymmetric autocatalysis, highly enantioenriched 5-pyrimidyl alkanol could be synthesized with their corresponding absolute configurations to those of chiral crystals of 2-pyridone and 4-aminopyr...
Source: Chirality - August 25, 2023 Category: Molecular Biology Authors: Arimasa Matsumoto Daisuke Tateishi Tsuyoshi Nakajima Shiori Kurosaki Tomohiro Ogawa Tsuneomi Kawasaki Kenso Soai Source Type: research
Achiral 2-pyridone and 4-aminopyridine act as chiral inducers of asymmetric autocatalysis with amplification of enantiomeric excess via the formation of chiral crystals
Chirality. 2023 Aug 24. doi: 10.1002/chir.23617. Online ahead of print.ABSTRACTEnantiomorphous crystals of achiral 2-pyridone and 4-aminopyridine served as sources of chirality, to induce the asymmetric autocatalysis of 5-pyrimidyl alkanol during the asymmetric addition of diisopropylzinc to the corresponding pyrimidine-5-carbaldehyde, that is, the Soai reaction. Following a significant amplification of enantiomeric excess through asymmetric autocatalysis, highly enantioenriched 5-pyrimidyl alkanol could be synthesized with their corresponding absolute configurations to those of chiral crystals of 2-pyridone and 4-aminopyr...
Source: Chirality - August 25, 2023 Category: Molecular Biology Authors: Arimasa Matsumoto Daisuke Tateishi Tsuyoshi Nakajima Shiori Kurosaki Tomohiro Ogawa Tsuneomi Kawasaki Kenso Soai Source Type: research
Achiral 2-pyridone and 4-aminopyridine act as chiral inducers of asymmetric autocatalysis with amplification of enantiomeric excess via the formation of chiral crystals
Chirality. 2023 Aug 24. doi: 10.1002/chir.23617. Online ahead of print.ABSTRACTEnantiomorphous crystals of achiral 2-pyridone and 4-aminopyridine served as sources of chirality, to induce the asymmetric autocatalysis of 5-pyrimidyl alkanol during the asymmetric addition of diisopropylzinc to the corresponding pyrimidine-5-carbaldehyde, that is, the Soai reaction. Following a significant amplification of enantiomeric excess through asymmetric autocatalysis, highly enantioenriched 5-pyrimidyl alkanol could be synthesized with their corresponding absolute configurations to those of chiral crystals of 2-pyridone and 4-aminopyr...
Source: Chirality - August 25, 2023 Category: Molecular Biology Authors: Arimasa Matsumoto Daisuke Tateishi Tsuyoshi Nakajima Shiori Kurosaki Tomohiro Ogawa Tsuneomi Kawasaki Kenso Soai Source Type: research
Achiral 2-pyridone and 4-aminopyridine act as chiral inducers of asymmetric autocatalysis with amplification of enantiomeric excess via the formation of chiral crystals
Chirality. 2023 Aug 24. doi: 10.1002/chir.23617. Online ahead of print.ABSTRACTEnantiomorphous crystals of achiral 2-pyridone and 4-aminopyridine served as sources of chirality, to induce the asymmetric autocatalysis of 5-pyrimidyl alkanol during the asymmetric addition of diisopropylzinc to the corresponding pyrimidine-5-carbaldehyde, that is, the Soai reaction. Following a significant amplification of enantiomeric excess through asymmetric autocatalysis, highly enantioenriched 5-pyrimidyl alkanol could be synthesized with their corresponding absolute configurations to those of chiral crystals of 2-pyridone and 4-aminopyr...
Source: Chirality - August 25, 2023 Category: Molecular Biology Authors: Arimasa Matsumoto Daisuke Tateishi Tsuyoshi Nakajima Shiori Kurosaki Tomohiro Ogawa Tsuneomi Kawasaki Kenso Soai Source Type: research
Achiral 2-pyridone and 4-aminopyridine act as chiral inducers of asymmetric autocatalysis with amplification of enantiomeric excess via the formation of chiral crystals
Chirality. 2023 Aug 24. doi: 10.1002/chir.23617. Online ahead of print.ABSTRACTEnantiomorphous crystals of achiral 2-pyridone and 4-aminopyridine served as sources of chirality, to induce the asymmetric autocatalysis of 5-pyrimidyl alkanol during the asymmetric addition of diisopropylzinc to the corresponding pyrimidine-5-carbaldehyde, that is, the Soai reaction. Following a significant amplification of enantiomeric excess through asymmetric autocatalysis, highly enantioenriched 5-pyrimidyl alkanol could be synthesized with their corresponding absolute configurations to those of chiral crystals of 2-pyridone and 4-aminopyr...
Source: Chirality - August 25, 2023 Category: Molecular Biology Authors: Arimasa Matsumoto Daisuke Tateishi Tsuyoshi Nakajima Shiori Kurosaki Tomohiro Ogawa Tsuneomi Kawasaki Kenso Soai Source Type: research
