Venus and Mars: influence of sex on diabetes and cardiometabolic disease
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - May 10, 2016 Category: Cardiology Tags: Editorials Source Type: research

Thirteenth World Congress on Insulin Resistance, Diabetes and Cardiovascular Disease: selected highlights, Los Angeles, California, USA, 19–21 November 2015
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - February 9, 2016 Category: Cardiology Tags: Short report Source Type: research

The effect of various stages of hypothermia on the ECG
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - February 9, 2016 Category: Cardiology Tags: Correspondence Source Type: research

The inflammatory biomarker YKL-40 decreases stepwise after exercise stress test
This study aimed to compare serial measurements of serum YKL-40 before and after exercise in patients with stable CAD versus controls. Materials and methods: Eleven patients with stable CAD verified by coronary angiography (>70% stenosis) and 11 patients with a computer tomography angiography with no stenosis or calcification (calcium score=0) (controls) performed a standard clinical maximal exercise test. Serum YKL-40 was measured before exercise, immediately after exercise, and every hour for 6 h. Results: Cardiovascular risk factors were more prevalent among the CAD patients compared with the controls. CAD patients ...
Source: Cardiovascular Endocrinology - February 9, 2016 Category: Cardiology Tags: Original articles Source Type: research

‘Knowing what matters in diabetes: healthier below 7’: results of the campaign’s first 10 years (part 1): participants with known type 2 diabetes
Conclusion: The analysis of PWD participating in the ‘Knowing what matters in diabetes: healthier below 7’ campaign showed that despite huge efforts in the past, important aspects for progression and complications of T2D mellitus are still not well controlled. This includes lifestyle habits as well as pharmaceutical treatment. Although the participants in this study cannot be considered a representative sample of the German population and occasional measurements without standardization further limit firm conclusions, the BP, plasma glucose, and HbA1c results indicate that a major proportion of PWD have insufficient met...
Source: Cardiovascular Endocrinology - February 9, 2016 Category: Cardiology Tags: Original articles Source Type: research

The role of lipoxins in cardiometabolic physiology and disease
Cardiometabolic pathophysiology is increasing in prevalence as a result of the escalating obesity pandemic. The search for novel therapeutics is ongoing and the strong interrelationship between diabetes and cardiovascular disease places emphasis on the need for drugs that target both pathologies, without interlinking side effects. Impaired inflammatory resolution may be the common denominator driving metabolic syndrome, diabetes, and cardiovascular disease. An interesting therapeutic approach would therefore be to promote the inflammatory resolution to subvert cardiometabolic disease. Inflammatory resolution is regulated b...
Source: Cardiovascular Endocrinology - February 9, 2016 Category: Cardiology Tags: Reviews Source Type: research

Blood pressure guidelines: beyond simple targets
Hypertension and blood pressure guidelines have developed incrementally over the years, keeping pace, and now outstripping, the clinical trials that have fuelled their opinions and recommendations. The focus has been very much on treatment thresholds and targets, so well suited to the medical model. However, the routine approach to blood pressure reduction in individuals of high cardiovascular risk, irrespective of their pressure and without a target, seem to slipped under the radar of the guidelines. It is time to rectify this significant oversight and take a broader view of treatment paradigms other than those based simp...
Source: Cardiovascular Endocrinology - February 9, 2016 Category: Cardiology Tags: Reviews Source Type: research

Conference report: 51st European Association for the Study of Diabetes (EASD) annual meeting 2015
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - November 11, 2015 Category: Cardiology Tags: Short report Source Type: research

Atypical antipsychotics and metabolic syndrome
Atypical antipsychotics have become the gold standard and the first treatment option for mental illness in recent years. However, despite all the benefits provided by these drugs, a growing collection of case reports and clinical trials describing metabolic complications and body weight gain have been reported. Among atypical antipsychotic drugs, olanzapine and clozapine appear to have the highest tendency to disturb glucose metabolism compared with the other antipsychotic drugs available on the market. (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - November 11, 2015 Category: Cardiology Tags: Review articles Source Type: research

Inflammation in diabetes and cardiovascular disease: a new perspective on vitamin D
Epidemiological studies indicate an inverse association between vitamin D level and chronic, low-grade systemic inflammatory diseases, such as type 2 diabetes mellitus and cardiovascular disease. Vitamin D signaling may interfere with transcription factors, such as nuclear factor-kappa B, which regulate the expression of inflammatory markers at several levels. In this review, the latest advances in the anti-inflammatory effects of vitamin D from experimental, observational, and small interventional studies will be discussed. (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - November 11, 2015 Category: Cardiology Tags: Review articles Source Type: research

Screening subclinical coronary artery disease with noninvasive modalities in patients with diabetes
Diabetes mellitus is a global epidemic crisis as well as a major risk factor for coronary artery disease. Although several well-known noninvasive screening modalities including cardiac computed tomography, echocardiography, and myocardial perfusion imaging have been examined, controversies exist on the prognostic efficacy of these tests. Little is known with regard to the cost–benefit ratios and potential harms of radiation, and no standard screening algorithms have been established. In this review, we discuss the need and criteria for good testing methods and then summarize some of the latest evidence from either random...
Source: Cardiovascular Endocrinology - November 11, 2015 Category: Cardiology Tags: Review articles Source Type: research

Professor Mike Cawthorne (1941–2015)
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - November 11, 2015 Category: Cardiology Tags: Obituary Source Type: research

The men who stare at science
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - November 11, 2015 Category: Cardiology Tags: Editorials Source Type: research

EMPA-REG OUTCOME: cardiovascular outcome trials in diabetes come of age
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - November 11, 2015 Category: Cardiology Tags: Editorials Source Type: research

Cardiometabolic effects of testosterone in older men
Several long-term studies have demonstrated that low levels of total and free testosterone are associated with increased cardiovascular and all-cause mortality in older men aged over 60 years. Low levels of testosterone are most commonly manifested by erectile dysfunction, reduced sexual desire, and loss of morning erections. Increasing numbers of older men demand treatment for these bothersome problems. Recent data suggest that testosterone replacement therapy may reduce cardiovascular mortality as well as improving multiple surrogate markers for cardiovascular events. The paradox preventing the routine measurement and tr...
Source: Cardiovascular Endocrinology - August 14, 2015 Category: Cardiology Tags: Invited reviews Source Type: research