Relative frequency of cardiology vs. endocrinology visits by type 2 diabetes patients with cardiovascular disease in the USA: implications for implementing evidence-based use of glucose-lowering medications
Cardiovascular disease (CVD) is a leading cause of morbidity and mortality in type 2 diabetes (T2D) patients. Recent cardiovascular outcome trials demonstrated clear cardiovascular benefits of novel classes of glucose-lowering agents. We performed retrospective electronic health record review at two major healthcare systems in the USA to determine the relative frequencies of outpatient encounters (hence prescribing opportunities) that a patient with T2D and CVD had with a cardiologist vs. an endocrinologist over one-year period. Of 109 747 T2D patients, 42.6% had established CVD. The ratio of cardiology-to-endocrinology ...
Source: Cardiovascular Endocrinology - May 19, 2020 Category: Cardiology Tags: Short Report Source Type: research
Associations of adiponectin and leptin with brain natriuretic peptide in African Americans: the Jackson Heart Study
Conclusions
Different linear associations of adiponectin and leptin with BNP were observed. Odds of elevated adiponectin were observed with elevated BNP in multivariate-adjusted models. This paradoxical relationship of adiponectin and plasma BNP is possibly explained through adiponectin resistance. (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - May 19, 2020 Category: Cardiology Tags: Original Articles Source Type: research
Sociodemographic and metabolic risk characteristics associated with metabolic weight categories in the Women’s Health Initiative
Objective
To identify sociodemographic and metabolic correlates of weight categories in postmenopausal women.
Methods
The Women’s Health Initiative enrolled 161 808 postmenopausal women ages 50–79. We included those free of cardiovascular disease (CVD) and with CVD risk factors and biomarkers (n = 19 412). Normal weight was defined as a BMI ≥18.5 and (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - May 19, 2020 Category: Cardiology Tags: Original Articles Source Type: research
A focused review of cardiovascular guideline related recommendations for the primary care physician in the USA
Primary care physicians in the USA serve the critical role of first contact for undiagnosed or mismanaged pathologies as well as providers of continuous care in multiple communities. Their scope of practice is broad from medication reconciliation to coordinating specialty care and even performing office procedures. Primary care physicians in the USA commonly encounter patients with diabetes and associated comorbidities related to prolonged insulin resistance. Mainly these include heart failure exacerbation or major adverse cardiovascular events. The demanding roles primary care physicians serve may render these providers e...
Source: Cardiovascular Endocrinology - May 19, 2020 Category: Cardiology Tags: Review Source Type: research
Ten tips for promoting your research
Publishing the results of scientific research is more than a personal choice; it is an ethical and increasingly regulatory obligation. It is generally accepted that top-ranking journals attract wider audiences than specialist publications and scientists have long recognised that the importance of targeting so-called high impact journal in getting their work noticed. However, gaining access to top-flight journals is difficult and a broader exposure is not necessarily guaranteed. Huge competition exists for attention within the scientific literature. Traditionally, scientists have viewed promoting their own research as somew...
Source: Cardiovascular Endocrinology - February 22, 2020 Category: Cardiology Tags: Viewpoint Source Type: research
Acute hyperglycemia and contrast-induced nephropathy in patients with non-ST elevation myocardial infarction
Introduction
Acute hyperglycemia and contrast-induced nephropathy (CIN) are frequently observed in non-ST elevation myocardial infarction (NSTEMI) patients undergoing percutaneous coronary intervention (PCI), and both are associated with an increased mortality rate. We investigated the possible association between acute hyperglycemia and CIN in patients with NSTEMI undergoing PCI.
Materials and methods
We retrospectively enrolled 281(149, 53% men) NSTEMI patients undergoing PCI. For each patient, plasma glucose levels were secreened at hospital admission. Acute hyperglycemia was defined as glucose levels> 198 mg/dl....
Source: Cardiovascular Endocrinology - February 22, 2020 Category: Cardiology Tags: Original Articles Source Type: research
Comparing inpatient costs of heart failure admissions for patients with reduced and preserved ejection fraction with or without type 2 diabetes
Conclusion
Overall cost was higher for patients with DM, whether or not they were admitted with acute HF due to HFrEF or HFpEF. Cost per day alive for patients with DM continued to exceed corresponding costs for patients without DM, with HFpEF patients with DM having the highest cost. (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - February 22, 2020 Category: Cardiology Tags: Original Articles Source Type: research
A treatment-based algorithm for identification of diabetes type in the National Health and Nutrition Examination Survey
Conclusion
Applying diabetes treatment information from the National Health and Nutrition Examination Survey, as formulated in our treatment-based algorithm, may better identify type 1 and type 2 diabetes cases and thus prevent the specific biases imposed by conventional approaches which include the age of diabetes diagnosis as an initial criterion for diabetes type classification. (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - February 22, 2020 Category: Cardiology Tags: Original Articles Source Type: research
Effects of aerobic and anaerobic exercise on glucose tolerance in patients with coronary heart disease and type 2 diabetes mellitus
Objectives
In patients with coronary heart disease (CHD) and type 2 diabetes mellitus (T2DM), physical activity is strongly advised as nonpharmacological therapy. In general, a moderate aerobic exercise intensity is recommended. It was also proposed, however, that greater intensities tend to yield even greater benefits in HbA1c. Hence, the most appropriate exercise intensity seems not to be established yet. We compared the effect of moderate (aerobic) and vigorous (anaerobic) activity on postprandial plasma glucose.
Methods
In 10 consecutive patients (63 ± 12 years, BMI 28.3 ± 2.6 kg/m2, fasting plasma g...
Source: Cardiovascular Endocrinology - February 22, 2020 Category: Cardiology Tags: Original Articles Source Type: research
Exercise prescription in patients with type 2 diabetes and coronary heart disease: could less be more?
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - February 22, 2020 Category: Cardiology Tags: Commentary Source Type: research
Ventricular fibrillation associated with Graves' disease and amiodarone induced thyrotoxicosis
This case involves a 55-year-old male patient with systolic heart failure and refractory atrial fibrillation due to thyrotoxicosis, who was electrically cardioverted but then developed torsade de pointes and ventricular fibrillation. Rate control was unsuccessful with digoxin, cardizem, labetalol, esmolol and amiodorone. Patient was externally cardioverted after which ECGs showed prolonged QT with frequent premature ventricular contractions. ECGs also showed ‘R-on-T' phenomenon leading to torsades and ventricular fibrillation. Atrial overdrive pacing was used to terminate the dangerous arrhythmia and the patient returned...
Source: Cardiovascular Endocrinology - November 8, 2019 Category: Cardiology Tags: Case Report Source Type: research
Left ventricular mass index and subendocardial myocardial function in children with chronic kidney disease, a transmural strain and three-dimensional echocardiographic study
This study has been conducted on 40 CKD patients (Group 1) and 40 age-matched controls, both groups were assessed by transmural echocardiography to determine the subepicardial and subendocardial global longitudinal strain (GLS) as an expression of the systolic function of each of those layers. LVH was assessed by calculation of left ventricle mass index (LVMI). Both groups underwent ambulatory blood pressure monitoring. Group 1 was assessed as regards lipid profile and insulin resistance by homeostasis model assessment of insulin resistance (HOMA-IR).
Results
HOMA-IR proved to be a more important determinant of LV hyper...
Source: Cardiovascular Endocrinology - November 8, 2019 Category: Cardiology Tags: Original Articles Source Type: research
The comparison of the relationships about the presence of branch retinal vein occlusion and endothelial functions between diabetic and non-diabetic patients
Objectives
The aim of this study was to investigate the endothelial functions in both patients with diabetics and non-diabetics with branch retinal vein occlusion by using pulse wave analysis and flow-mediated dilatation methods.
Patients and methods
This cross-sectional study included a total of 136 participants (47 diabetic patients with branch retinal vein occlusion, 43 non-diabetic patients with branch retinal vein occlusion, and 46 otherwise healthy subjects). Evaluation of endothelial functions was performed by flow-mediated dilatation and pulse wave analysis methods. Stiffness index, reflection index (RI), and ...
Source: Cardiovascular Endocrinology - November 8, 2019 Category: Cardiology Tags: Original Articles Source Type: research
Estimation of apolipoprotein A in early onset ST-segment elevation myocardial infarction
This study sought to assess the apolipoprotein A in cohort of patients diagnosed with early onset acute ST-segment elevation myocardial infarction and to corelate it with major traditional cardiovascular risk factors.
Methods
A total of 50 such patients and 40 age and sex-matched healthy controls, both aged less than 50 years with their baseline demographic, clinical characteristics and cardiovascular risk factors were studied. Apolipoprotein A was estimated for all enrollees.
Results
The mean age of cases was 43.37 ± 5.85 years. The levels of apolipoprotein A among cases were not significantly lower compared to con...
Source: Cardiovascular Endocrinology - November 8, 2019 Category: Cardiology Tags: Original Articles Source Type: research
Cardioprotective diabetes drugs: what cardiologists need to know
In patients with diabetes, where cardiovascular morbidity is highly prevalent, recent cardiovascular outcomes trials have identified therapies in the modern glucagon-like peptide 1 receptor agonist (GLP-1RA) and sodium-glucose cotransporter 2 inhibitor (SGLT2i) classes that significantly reduce cardiovascular events. A number of drugs in both classes have demonstrated reductions in the risk of the composite outcome of major adverse cardiovascular events (myocardial infarction, stroke, and cardiovascular death). In addition, SGLT2i drugs have a substantial impact on hospitalization for heart failure. Because GLP-1RA and SGL...
Source: Cardiovascular Endocrinology - November 8, 2019 Category: Cardiology Tags: Review Articles Source Type: research
