Epidemiology in diabetes mellitus and cardiovascular disease
As one of the leading causes of death in the USA, diabetes mellitus (DM) has become an epidemic over the past few decades. Despite the high prevalence of diagnosed DM, close to half of all people with DM are unaware of their disease. The risk of type 2 DM is determined by interplay of genetic and metabolic factors. Patients with type 2 DM have a higher risk of death from cardiovascular causes compared with their nondiabetic counterparts, and the mortality rate of DM associated cardiovascular disease is different among ethnicity groups and sex groups. Because of its adverse effect on people’s health, DM also imposes an ec...
Source: Cardiovascular Endocrinology - February 16, 2017 Category: Cardiology Tags: Review Articles Source Type: research
The emergence of cardiodiabetology
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - February 16, 2017 Category: Cardiology Tags: Review Articles Source Type: research
Cardiodiabetology: The convergence of diabetes and cardiovascular disease
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - February 16, 2017 Category: Cardiology Tags: Editorials Source Type: research
Editorial introduction
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - February 16, 2017 Category: Cardiology Tags: Editorials Source Type: research
Highlights of selected presentations on clinical aspects of hypertension and type 2 diabetes from the 52nd European Association for the Study of Diabetes conference in Munich September 2016.
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - November 12, 2016 Category: Cardiology Tags: Commentary: PDF Only Source Type: research
Is a reduction in brown adipose thermogenesis responsible for the change in core body temperature at menopause?
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - November 12, 2016 Category: Cardiology Tags: Commentary Source Type: research
Core body temperature is lower in postmenopausal women than premenopausal women: potential implications for energy metabolism and midlife weight gain
Objective: Weight gain during the menopausal transition is common. Although studies have suggested that weight gain is more likely related to aging than menopause, there is a reduction in resting energy expenditure with surgical or natural menopause that is independent of age and changes in body composition. The underlying mechanisms could include a reduction in core body temperature.
Methods: Data were obtained from two related studies. Sample size was 23 men and 25 women (12 premenopausal, 13 postmenopausal). In the Clinical Research Unit, core temperature was measured every minute for 24 h using an ingested temperatu...
Source: Cardiovascular Endocrinology - November 12, 2016 Category: Cardiology Tags: Short Report Source Type: research
New diagnostics for hypertension in diabetes and the role of chronotherapy: a new perspective
Globally, diabetes has become one of the major causes of premature morbidity and mortality, and this is mainly attributable to the increased risk of cardiovascular (CV) disease. CV risk stratification is based on well-established risk factors including hypertension, diabetes, dyslipidaemia, smoking, age and sex. However, current assessment models are imperfect. Improved risk stratification may be achieved by the use of home and ambulatory blood pressure (BP) monitoring. Identification of new CV risk factors, which add prognostic information, may also improve risk stratification. Pulse wave velocity and central BP have been...
Source: Cardiovascular Endocrinology - November 12, 2016 Category: Cardiology Tags: Review Articles Source Type: research
Hypertension in type 2 diabetes: impact of glucose-lowering medications
Hypertension often co-exists with hyperglycaemia to elevate the risk of vascular disease. The importance of treating hypertension in type 2 diabetes is well appreciated, the benefits of good glycaemic control and effective treatment of hypertension being additive. Treating hyperglyaemia on the one hand and hypertension on the other are usually considered separate strategies of a multifactorial approach to risk reduction requiring specific antihypertensive and glucose-lowering drugs. It is well appreciated that antihypertensive medications can have effects (prodiabetic, neutral, protective against diabetes, according to dru...
Source: Cardiovascular Endocrinology - November 12, 2016 Category: Cardiology Tags: Review Articles Source Type: research
Early vascular ageing as a new model to understand hypertension and arterial disease
Hypertension is a major cardiovascular risk factor and can be treated. The cardiovascular risk associated with hypertension, however, cannot be fully reversed by treatment with blood pressure-lowering drugs. One reason could be that not all risk factors are addressed at the same time, but another reason could well be that structural changes and remodelling of the arterial wall are not diminished nor normalized. One component that has attracted considerable research efforts in recent years is arterial stiffness, primarily involving the arteria media (elastin, collagen), but also the arterial intima and adventitia. Arterial ...
Source: Cardiovascular Endocrinology - November 12, 2016 Category: Cardiology Tags: Review Articles Source Type: research
Diabetes and hypertension: too many guidelines, not enough data
The early diagnosis, appropriate management, and pharmacological treatment of hypertension in those with diabetes mellitus are key in preventing and reducing the significant risk of cardiovascular disease-related morbidity and mortality in this patient population. Despite the universal recognition of the importance of hypertension management in those with diabetes mellitus, there still remains controversy on the appropriate blood pressure at which to initiate pharmacologic therapy and, once initiated, what blood pressure goal to achieve. This paper will review current blood pressure recommendations published in recent majo...
Source: Cardiovascular Endocrinology - November 12, 2016 Category: Cardiology Tags: Review Articles Source Type: research
Blood pressure targets in type 2 diabetes: a general perspective
Blood pressure targets in patients with type 2 diabetes are currently being debated. This review summarizes the current treatment recommendations provided in American and European guidelines, and findings from systematic reviews and meta-analyses published during the last decade. We critically assess the basis for the recommendations provided in relation to the evidence presented in reviews. When reviews differ in their results, we discuss the reasons for such differences. The results from recent studies in patients without diabetes and their potential implications for recommendations in patients with diabetes are commente...
Source: Cardiovascular Endocrinology - November 12, 2016 Category: Cardiology Tags: Review Articles Source Type: research
Hypertension, diabetes and blood pressure targets: ongoing challenges
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - November 12, 2016 Category: Cardiology Tags: Editorials Source Type: research
Introduction to a special issue: hypertension in type 2 diabetes
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - November 12, 2016 Category: Cardiology Tags: Editorials Source Type: research
Editorial introductions
No abstract available (Source: Cardiovascular Endocrinology)
Source: Cardiovascular Endocrinology - November 12, 2016 Category: Cardiology Tags: Editorial introductions Source Type: research
