Inflammation in diabetes and cardiovascular disease: a new perspective on vitamin D

Epidemiological studies indicate an inverse association between vitamin D level and chronic, low-grade systemic inflammatory diseases, such as type 2 diabetes mellitus and cardiovascular disease. Vitamin D signaling may interfere with transcription factors, such as nuclear factor-kappa B, which regulate the expression of inflammatory markers at several levels. In this review, the latest advances in the anti-inflammatory effects of vitamin D from experimental, observational, and small interventional studies will be discussed.
Source: Cardiovascular Endocrinology - Category: Cardiology Tags: Review articles Source Type: research