Target volumes comparison between postoperative simulation magnetic resonance imaging and preoperative diagnostic magnetic resonance imaging for prone breast radiotherapy after breast ‐conserving surgery
ConclusionsDespite using DIR technology, the spatial correspondence of target volumes between MRIpre and MRIpost was suboptimal. Therefore, relying solely on preoperative diagnostic MRI with DIR for postoperative LC delineation is not recommended. (Source: Cancer Medicine)
Source: Cancer Medicine - January 22, 2024 Category: Cancer & Oncology Authors: Ying Jin,
Changhui Zhao,
Lizhen Wang,
Ya Su,
Dongping Shang,
Fengxiang Li,
Jinzhi Wang,
Xijun Liu,
Jianbin Li,
Wei Wang Tags: RESEARCH ARTICLE Source Type: research
A systematic literature review of the human papillomavirus prevalence in locally and regionally advanced and recurrent/metastatic head and neck cancers through the last decade: The “ALARM” study
ConclusionOver the last decade, at least one quarter of LA/RM HNC and half of OPC cases studied in IS and NIS were HPV+. This alarming burden is consistent with a potential implication of HPV in the pathogenesis of at least a subgroup of HNC, underscoring the relevance of HPV testing and prophylaxis to HNC prevention and management. (Source: Cancer Medicine)
Source: Cancer Medicine - January 22, 2024 Category: Cancer & Oncology Authors: Sofia Agelaki,
Ioannis Boukovinas,
Ilias Athanasiadis,
Georgios Trimis,
Ioannis Dimitriadis,
Lazaros Poughias,
Edith Morais,
Ugne Sabale,
Goran Bencina,
Charalampos Athanasopoulos Tags: REVIEW Source Type: research
Retinoblastoma treatment in a Brazilian population. Presentation and long ‐term results
ConclusionsTreatment of retinoblastoma with conservative systemic-based chemotherapy was associated with an excellent survival rate (92%). Albeit the low overall globe salvage rate, in BIL patients, approximately half the eyes were conserved, and a satisfactory functional visual result was achieved The evaluated protocol is an important treatment option, especially in developing countries. (Source: Cancer Medicine)
Source: Cancer Medicine - January 20, 2024 Category: Cancer & Oncology Authors: Maria Teresa Brizzi Chizzotti Bonanomi,
Maria Tereza A. de Almeida,
Marianna A. Hollaender,
Roberta Chizzotti Bonanomi,
Mario Luiz Ribeiro Monteiro Tags: RESEARCH ARTICLE Source Type: research
Issue Information
(Source: Cancer Medicine)
Source: Cancer Medicine - January 19, 2024 Category: Cancer & Oncology Tags: ISSUE INFORMATION Source Type: research
Identifying determinants of adherence to adjuvant endocrine therapy following breast cancer: A systematic review of reviews
ConclusionsThe evidence-base on ET adherence determinants is extensive. Future empirical studies should focus on less well-researched areas and settings. The determinants themselves are numerous and complex in indicating that adherence support should be multifaceted, addressing multiple determinants. (Source: Cancer Medicine)
Source: Cancer Medicine - January 19, 2024 Category: Cancer & Oncology Authors: Adam Todd,
Catherine Waldron,
Lucy McGeagh,
Ruth Norris,
Iakov Bolnykh,
Sarah Jane Stewart,
Joanna Slodkowska ‐Barabasz,
Zoe Moon,
Caitriona Cahir,
Sue Thompson,
Victoria Harmer,
Mary Wells,
Eila Watson,
Linda Sharp,
the SWEET Research Tea Tags: RESEARCH ARTICLE Source Type: research
Neurocognitive and psychosocial outcomes in survivors of childhood leukemia with Down syndrome
ConclusionChildren with Down syndrome (DS) are at increased risk for developing acute leukemia compared to the general population but are systematically excluded from neurocognitive outcome studies among leukemia survivors. This study demonstrated the feasibility of evaluating neurocognitive late effects in leukemia survivors with DS using novel measures appropriate for populations with intellectual developmental disorder. (Source: Cancer Medicine)
Source: Cancer Medicine - January 19, 2024 Category: Cancer & Oncology Authors: Kellen Gandy,
Lacey Hall,
Kevin R. Krull,
Anna J. Esbensen,
Jeffrey Rubnitz,
Lisa M. Jacola Tags: RESEARCH ARTICLE Source Type: research
Tumor therapy by targeting extracellular hydroxyapatite using novel drugs: A paradigm shift
ConclusionDissolution of TME-HAP using our novel NSPS has the potential to provide a new treatment paradigm to enhance the management of cancer patients with poor prognosis. (Source: Cancer Medicine)
Source: Cancer Medicine - January 19, 2024 Category: Cancer & Oncology Authors: Mohammed N. Tantawy,
J. Oliver McIntyre,
Fiona Yull,
M. Wade Calcutt,
Dmitry S. Koktysh,
Andrew J. Wilson,
Zhongliang Zu,
Jeff Nyman,
Julie Rhoades,
Todd E. Peterson,
Daniel Colvin,
Lisa J. McCawley,
Jerri. M. Rook,
Barbara Fingleton,
Marta Tags: RESEARCH ARTICLE Source Type: research
Gut microbiota, microbiota ‐derived metabolites, and graft‐versus‐host disease
AbstractAllogeneic hematopoietic stem cell transplantation is one of the most effective treatment strategies for leukemia, lymphoma, and other hematologic malignancies. However, graft-versus-host disease (GVHD) can significantly reduce the survival rate and quality of life of patients after transplantation, and is therefore the greatest obstacle to transplantation. The recent development of new technologies, including high-throughput sequencing, metabolomics, and others, has facilitated great progress in understanding the complex interactions between gut microbiota, microbiota-derived metabolites, and the host. Of these in...
Source: Cancer Medicine - January 19, 2024 Category: Cancer & Oncology Authors: XiaoYan Yue,
Hongyu Zhou,
ShuFen Wang,
Xu Chen,
HaoWen Xiao Tags: REVIEW Source Type: research
Correction to “Impacts of pre‐existing diabetes mellitus on colorectal cancer in a mice model”
(Source: Cancer Medicine)
Source: Cancer Medicine - January 18, 2024 Category: Cancer & Oncology Tags: CORRECTION Source Type: research
Clinicopathological comparison between PTCL ‐TBX21 and PTCL‐GATA3 in Japanese patients
ConclusionThe classification of PTCL-NOS into PTCL-TBX21 and PTCL-GATA3 is useful for predicting the prognosis of Japanese patients and stratifying the administration of tumor immune checkpoint inhibitors in clinical practice. (Source: Cancer Medicine)
Source: Cancer Medicine - January 18, 2024 Category: Cancer & Oncology Authors: Yasumasa Shimasaki,
Hiroaki Miyoshi,
Keisuke Kawamoto,
Noriaki Yoshida,
Tatsuzo Mishina,
Kazutaka Nakashima,
Teppei Imamoto,
Takeshi Sugio,
Eriko Yanagida,
Takeharu Kato,
Kyohei Yamada,
Mai Takeuchi,
Takaharu Suzuki,
Mayuko Moritsubo,
Takuya Tags: RESEARCH ARTICLE Source Type: research
Disparities in care of older adults of color with cancer: A narrative review
Older adults of color with cancer face healthcare disparities related to both their race/ethnicity and age. Many interconnected factors contribute to these disparities including clinical, age-related physiologic, and treatment-related factors, as well as the social determinants of health related to healthcare access, socioeconomic concerns, systemic racism, mistrust, and the neighborhood or built environment where a person lives. To allow for early identification of these factors and personalized management for older patients of color with cancer, we advocate for widespread implementation of an enhanced geriatric assessmen...
Source: Cancer Medicine - January 18, 2024 Category: Cancer & Oncology Authors: Efrat Dotan,
Shannon M. Lynch,
Joanne C. Ryan,
Edith P. Mitchell Tags: REVIEW Source Type: research
Racial differences in treatment and survival among older patients with multiple myeloma
ConclusionsThe increasing racial disparity in treatment utilization over time is concerning. Efforts are needed to eliminate the barriers of receiving treatment. (Source: Cancer Medicine)
Source: Cancer Medicine - January 18, 2024 Category: Cancer & Oncology Authors: Rong Wang,
Natalia Neparidze,
Xiaomei Ma,
Graham A. Colditz,
Su ‐Hsin Chang,
Shi‐Yi Wang Tags: RESEARCH ARTICLE Source Type: research
Opportunistic lung cancer screening with low ‐dose computed tomography in National Cancer Center of China: The first 14 years' experience
ConclusionsIn our study, using LDCT for lung cancer screening proved significant for high-risk individuals. For non-high-risk populations, LDCT screening could be considered for nonsmoking women with exposure to SHS. (Source: Cancer Medicine)
Source: Cancer Medicine - January 18, 2024 Category: Cancer & Oncology Authors: Wei Tang,
Li Liu,
Yao Huang,
Shijun Zhao,
Jianwei Wang,
Min Liang,
Yujing Jin,
Lina Zhou,
Ying Liu,
Yanyan Tang,
Zhijian Xu,
Kai Zhang,
Fengwei Tan,
Nan Bi,
Zhijie Wang,
Fei Wang,
Ni Li,
Ning Wu Tags: RESEARCH ARTICLE Source Type: research
The augmentation of cytotoxic immune cell functionality through physical exertion bolsters the potency of chemotherapy in models of mammary carcinoma
ConclusionsPhysical training improves the effectiveness of doxorubicin in treating breast cancer by activating cytotoxic immune cells, releasing tumor suppressor factors, and initiating mt-apoptosis, all while mitigating the adverse effects of chemotherapy. (Source: Cancer Medicine)
Source: Cancer Medicine - January 18, 2024 Category: Cancer & Oncology Authors: Bingqing Qin,
Zhongshi He,
Lixia Xie,
Shenglan Feng,
Junjie Ye,
Jianjun Gui,
Xiaodong Sun,
Ming Sang Tags: RESEARCH ARTICLE Source Type: research
Machine learning ‐based model constructed from ultrasound radiomics and clinical features for predicting HER2 status in breast cancer patients with indeterminate (2+) immunohistochemical results
ConclusionsMachine learning models grounded on radiomics efficiently predicted IHC HER2 2+ status in breast cancer patients, suggesting potential enhancements in clinical decision-making for treatment and management. (Source: Cancer Medicine)
Source: Cancer Medicine - January 18, 2024 Category: Cancer & Oncology Authors: Meiying Yan,
Jincao Yao,
Xiao Zhang,
Dong Xu,
Chen Yang Tags: RESEARCH ARTICLE Source Type: research
