Efficacy and safety of atezolizumab plus bevacizumab in patients with portal hypertension for unresectable hepatocellular carcinoma
ConclusionsNo significant differences in efficacy and safety were observed with PH. Prophylactic treatment for varices before the start of Atezo + Beva would allow treatment to continue relatively safely. (Source: Cancer Medicine)
Source: Cancer Medicine - March 13, 2024 Category: Cancer & Oncology Authors: Takahiro Kinami,
Shinsuke Uchikawa,
Tomokazu Kawaoka,
Shintaro Yamasaki,
Masanari Kosaka,
Yusuke Johira,
Shigeki Yano,
Kei Amioka,
Kensuke Naruto,
Kenji Yamaoka,
Yasutoshi Fujii,
Hatsue Fujino,
Takashi Nakahara,
Atsushi Ono,
Eisuke Murakami, Tags: RESEARCH ARTICLE Source Type: research
Anatomic versus non ‐anatomic liver resection for hepatocellular carcinoma—A European multicentre cohort study in cirrhotic and non‐cirrhotic patients
ConclusionNo significant differences on RFS and OS rates could be observed. Post-operative complications were significantly less frequent in the ALR group while liver specific complications were comparable between both groups. Subgroup analysis showed no significant influence of cirrhosis on the post-operative outcome of these patients. (Source: Cancer Medicine)
Source: Cancer Medicine - March 13, 2024 Category: Cancer & Oncology Authors: Jasmin Zeindler,
Gabriel Fridolin Hess,
Maximilian von Heesen,
Noa Aegerter,
Cornelia Reber,
Andreas Michael Schmitt,
Simone Muenst,
Martin Bolli,
Savas Deniz Soysal,
Otto Kollmar Tags: RESEARCH ARTICLE Source Type: research
Significance of the cribriform morphology area ratio for biochemical recurrence in Gleason score 4 + 4 prostate cancer patients following robot‐assisted radical prostatectomy
ConclusionsAn increased % cribriform value was associated with BCR in patients with GS 4 + 4 prostate cancer following RARP. (Source: Cancer Medicine)
Source: Cancer Medicine - March 13, 2024 Category: Cancer & Oncology Authors: Kenji Shimodaira,
Rie Inoue,
Takeshi Hashimoto,
Naoya Satake,
Toshihide Shishido,
Kazunori Namiki,
Kazuharu Harada,
Toshitaka Nagao,
Yoshio Ohno Tags: RESEARCH ARTICLE Source Type: research
Nomogram for predicting pathologic complete response to neoadjuvant chemoradiotherapy in patients with esophageal squamous cell carcinoma
ConclusionsFemale, earlier cN stage, duration of nCRT (< 62 days), chemotherapy regimen of taxane plus platinum, pre-nCRT NLR (≥2.199), and pre-nCRT PLR (≥99.302) were significantly associated with a higher pCR in ESCC patients whose primary chemotherapy was a taxane-based regimen for nCRT. A nomogram was developed and internally validated, showi ng good accuracy and consistency. (Source: Cancer Medicine)
Source: Cancer Medicine - March 13, 2024 Category: Cancer & Oncology Authors: Guihong Liu,
Tao Chen,
Xin Zhang,
Binbin Hu,
Jiayun Yu Tags: RESEARCH ARTICLE Source Type: research
Glycemic traits and colorectal cancer survival in a cohort of South Korean patients: A Mendelian randomization analysis
ConclusionsOur results suggest that FG and HbA1c could be used to predict prognosis in CRC patients. Lifestyle and/or pharmacological interventions targeting glycemic traits could help improve survival for CRC patients. (Source: Cancer Medicine)
Source: Cancer Medicine - March 13, 2024 Category: Cancer & Oncology Authors: So Yon Jun,
Sooyoung Cho,
Min Jung Kim,
Ji Won Park,
Seung ‐Bum Ryoo,
Seung Yong Jeong,
Kyu Joo Park,
Aesun Shin Tags: RESEARCH ARTICLE Source Type: research
Clinical value of endoscopic ultrasound sound speed in differential diagnosis of pancreatic solid lesion and prognosis of pancreatic cancer
ConclusionsSS plays a vital role in distinguishing between PBL and PC. Higher SS1 and ratio1 obtained by EUS are more related to PC than PBL. In PC patients, high SS1 may predict pancreatic lesions. In the nonsurgical group of PC, low ratio1 may predict high OS. However, in the surgical group of PC, low SS1 may predict low OS. (Source: Cancer Medicine)
Source: Cancer Medicine - March 13, 2024 Category: Cancer & Oncology Authors: Jianing Qiu,
Kangrong Li,
Xiuyan Long,
Xiaoyu Yu,
Pan Gong,
Yu Long,
Xiaoyan Wang,
Li Tian Tags: RESEARCH ARTICLE Source Type: research
Global burden, risk factors, and trends of non ‐Hodgkin lymphoma: A worldwide analysis of cancer registries
ConclusionsThis study indicates a rising trend of NHL incidence over the past decade- particularly in developed countries, older males, and younger populations. Further research should investigate deeper insights into specific etiology and prognosis of NHL across subtypes, and potential contributors towards these epidemiologic trends. (Source: Cancer Medicine)
Source: Cancer Medicine - March 13, 2024 Category: Cancer & Oncology Authors: Junjie Huang,
Sze Chai Chan,
Veeleah Lok,
Lin Zhang,
Don Eliseo Lucero ‐Prisno III,
Wanghong Xu,
Zhi‐Jie Zheng,
Edmar Elcarte,
Mellissa Withers,
Martin C. S. Wong Tags: RESEARCH ARTICLE Source Type: research
Urban relatives ameliorate survival disparities for genitourinary cancer in rural patients
ConclusionsOur findings suggest rural patients who have been diagnosed with a genitourinary cancer have improved survival when having relatives in urban centers relative to rural patients without urban relatives. Further research is needed to better understand the mechanisms through which having an urban family member contributes to improved cancer outcomes for rural patients. Better characterization of this affect may help inform policies to reduce urban –rural cancer disparities. (Source: Cancer Medicine)
Source: Cancer Medicine - March 13, 2024 Category: Cancer & Oncology Authors: Mouneeb Choudry,
Kassandra Dindinger ‐Hill,
Jacob Ambrose,
Joshua Horns,
Jeffrey Vehawn,
Hailie Gill,
Nicole Z. Murray,
Trevor E. Hunt,
Christopher Martin,
Benjamin Haaland,
Jonathan Chipman,
Heidi A. Hanson,
Brock B. O'Neil Tags: RESEARCH ARTICLE Source Type: research
Brain metastases in patients with salivary duct carcinoma: A retrospective study
ConclusionThe SDC-GPA score emerged as a useful prognostication tool for patients with BM. (Source: Cancer Medicine)
Source: Cancer Medicine - March 13, 2024 Category: Cancer & Oncology Authors: Chihiro Fushimi,
Hideaki Takahashi,
Daisuke Kawakita,
Satoshi Kano,
Kiyoaki Tsukahara,
Hiroyuki Ozawa,
Kenji Okami,
Akihiro Sakai,
Keisuke Yamazaki,
Takuro Okada,
Toyoyuki Hanazawa,
Yuichiro Sato,
Yorihisa Imanishi,
Akira Shimizu,
Takashi Ma Tags: RESEARCH ARTICLE Source Type: research
Retraction: lncRNA ABHD11 ‐AS1, regulated by the EGFR pathway, contributes to the ovarian cancer tumorigenesis by epigenetically suppressing TIMP2
AbstractXiang-Yang Zeng, Xiao-Yan Jiang, Jia-Hui Yong, Hui Xie, Jing Yuan, Da Zeng, Ying-Yu Dou, Song-Shu Xiao “lncRNA ABHD11-AS1, regulated by the EGFR pathway, contributes to the ovarian cancer tumorigenesis by epigenetically suppressing TIMP2” Cancer Med. 2019; 8: 7074–7085 (https://doi.org/10.1002/cam4.2586)The above article, published online on 30 September 2019, in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal's Editor-in-Chief, Stephen Tait, and John Wiley and Sons Ltd. Following publication, concerns were raised by a third party regarding image overlap wi...
Source: Cancer Medicine - March 13, 2024 Category: Cancer & Oncology Tags: RETRACTION Source Type: research
Prediction of prognosis in oral squamous cell carcinoma using infrared microspectroscopy
ConclusionThe data suggest that FTIR spectra may be a useful early biomarker of prognosis in OSCC. (Source: Cancer Medicine)
Source: Cancer Medicine - March 12, 2024 Category: Cancer & Oncology Authors: Conor A. Whitley,
Barnaby G. Ellis,
Asterios Triantafyllou,
Philip J. Gunning,
Peter Gardner,
Steve D. Barrett,
Richard J. Shaw,
Caroline I. Smith,
Peter Weightman,
Janet M. Risk Tags: RESEARCH ARTICLE Source Type: research
Combination tumor ‐treating fields treatment for patients with metastatic non‐small cell lung cancer: A cost‐effectiveness analysis
ConclusionsIn the United States, TTFields plus SOC as second-line treatment was not a more cost-effective strategy for patients with mNSCLC. Of the analyzed regimens, TTFields plus ICI was associated with most significant health benefits. (Source: Cancer Medicine)
Source: Cancer Medicine - March 12, 2024 Category: Cancer & Oncology Authors: Kun Liu,
Youwen Zhu,
Hong Zhu,
Manting Zeng Tags: RESEARCH ARTICLE Source Type: research
Causal associations between atrial fibrillation and breast cancer: A bidirectional Mendelian randomization analysis
ConclusionsOur bidirectional MR studies revealed that there may be no causal links between atrial fibrillation and breast cancer. (Source: Cancer Medicine)
Source: Cancer Medicine - March 12, 2024 Category: Cancer & Oncology Authors: Zhaoting Gong,
Mengjin Hu,
Yuejin Yang,
Chunlin Yin Tags: RESEARCH ARTICLE Source Type: research
Comprehensive analysis indicated that NDE1 is a potential biomarker for pan ‐cancer and promotes bladder cancer progression
ConclusionHigh expression of NDE1 is present in a variety of tumours, which is linked to a bad prognosis for cancer. Knockdown of NDE1 inhibited the proliferation, invasion and metastasis of bladder cancer cells, and promoted the apoptosis. For a number of malignancies, NDE1 may be a biomarker for immunotherapy and prognosis. (Source: Cancer Medicine)
Source: Cancer Medicine - March 11, 2024 Category: Cancer & Oncology Authors: Peihan Wang,
Jinzhuo Ning,
Wu Chen,
Fan Zou,
Weimin Yu,
Ting Rao,
Fan Cheng Tags: RESEARCH ARTICLE Source Type: research
Survival of the Hmong population diagnosed with colon and rectal cancers in the United States
ConclusionsHmong individuals are nearly a decade younger at the time of diagnosis of CRC compared to the NHW individuals. However, these data do not suggest an association between Hmong ethnicity and overall survival, when compared to the NHW population. (Source: Cancer Medicine)
Source: Cancer Medicine - March 11, 2024 Category: Cancer & Oncology Authors: Margaret R. Walker,
Kha Lor,
Kajua B. Lor,
Roberto J. Vidri,
John M. Hampton,
Cinthya Maldonado,
Andrea M. Schiefelbein,
Noelle K. LoConte Tags: RESEARCH ARTICLE Source Type: research
