Dose-Dense Docetaxel-Cyclophosphamide and Epirubicin-Cisplatin(ddDCEP): Analysis of an alternative platinum-containing regimen in 116 patients with early triple negative breast cancer
Cancer Invest. 2023 Nov 1:1-18. doi: 10.1080/07357907.2023.2278048. Online ahead of print.ABSTRACTWe assessed the efficacy, tolerability, and cost-effectiveness of a novel neoadjuvant regimen comprising docetaxel-cyclophosphamide alternating with epirubicin-cisplatin (ddDCEP) administered biweekly for 16 weeks in 116 patients with early triple-negative breast cancer. This regimen achieved a high pathological complete response (ypT0/TisN0) rate of 55.2% and favorable survival outcomes (30-month event-free survival, 91.2%; overall survival, 97%). Febrile neutropenia was observed in 4.3% of patients, and 98% completed at leas...
Source: Cancer Investigation - November 1, 2023 Category: Cancer & Oncology Authors: Ashish Singh Josh Thomas Georgy Anjana Joel Divya Bala Thumaty Ajoy Oommen John Nithya Ramnath Tarun K George Parth Sharma Shalom Patole Grace Rebekah Elanthenral Sigamani Marie Therese Manipadam Anish Jacob Cherian Deepak Thomas Abraham Mazhuvanchary Jac Source Type: research
Anxiety, depression and coping strategies during chemotherapy treatment: A comparison of older and younger adults with advanced cancer in Brazil
Cancer Invest. 2023 Oct 26:1-18. doi: 10.1080/07357907.2023.2274033. Online ahead of print.ABSTRACTWe sought to examine differences in anxiety, depression and coping strategies among younger (<64 years old) and older (≥65 years old) patients. Patients were assessed at baseline (T1), mid-point (T2) and on the last day of treatment (T3) using the Hospital Anxiety and Depression Scale and the Ways of Coping. Linear mixed modeling approach was used. The study included 200 patients (gender: 70% women; diagnosis: 30% breast, 22% hematological, 18% gastrointestinal; disease stage: 60% advanced). Older patients who used an em...
Source: Cancer Investigation - October 26, 2023 Category: Cancer & Oncology Authors: Cristiane Decat Bergerot Errol J Philip Paulo Gustavo Bergerot Marianne Razavi David Lee Karen Lynn Clark Matthew Loscalzo Sumanta Kumar Pal William Dale Source Type: research
The Nature, Origin and Evolution of Life: Part II The Origin of Life
Cancer Invest. 2023 Oct 11:1-4. doi: 10.1080/07357907.2023.2270277. Online ahead of print.NO ABSTRACTPMID:37818859 | DOI:10.1080/07357907.2023.2270277 (Source: Cancer Investigation)
Source: Cancer Investigation - October 11, 2023 Category: Cancer & Oncology Authors: Gary H Lyman Christopher H Lyman Nicole M Kuderer Source Type: research
