COVID-19 Outbreak Impact on Cancer Multidisciplinary Team Meetings. A Multicenter French Experience
Cancer Invest. 2024 Feb 5:1-8. doi: 10.1080/07357907.2024.2311856. Online ahead of print.ABSTRACTMultidisciplinary team meeting (MDT) became a standard of care in cancer management. The COVID-19 epidemic induced unprecedented pressure on the health system. The impact of this health crisis on MDTs held within a regional French health structures was analyzed. A decrease in the total number of records discussed in hematological, digestive, thoracic, gynecological and genitourinary MDTs was observed following the 1st wave of the COVID-19 pandemic. This decrease was generally maintained during the 2nd and 3rd wave. MDTs activit...
Source: Cancer Investigation - February 6, 2024 Category: Cancer & Oncology Authors: Wafa Bouleftour Amandine Mondiere-Wichurski Pierre Fournel Quentin Reboul Source Type: research
Gain of Chromosome 5q Predicts a Favorable Prognosis in Localized Renal Cell Carcinoma
Cancer Invest. 2024 Feb 5:1-7. doi: 10.1080/07357907.2024.2308172. Online ahead of print.ABSTRACTApproximately 65% of renal cell carcinomas (RCC) are diagnosed at a localized stage. We investigated the chromosome 5q gain impact on disease-free survival (DFS) in RCC patients. Overall, 676 patients with stages 1-2 RCC and having cytogenetic analysis were included. Gain of 5q was observed in 108 patients, more frequently in clear cell (ccRCC) than non-clear cell tumors. Gain of 5q is likely an independent prognostic factor since the concerned patients had a decreased recurrence risk in stages 1-2 RCC, confirmed in multivariab...
Source: Cancer Investigation - February 5, 2024 Category: Cancer & Oncology Authors: Cedric Lebacle Aydin Pooli Brian Shuch Nagesh Rao Karim Chamie Nils Kroeger Izak Faiena Sandy Liu Erika L Wood Arie Belldegrun Alexandra Drakaki Allan J Pantuck Source Type: research
The Nature, Origin, and Evolution of Life: Part V Bringing It Together: Concepts, Constraints, and Closure
Cancer Invest. 2024 Feb 1:1-4. doi: 10.1080/07357907.2024.2309792. Online ahead of print.NO ABSTRACTPMID:38303557 | DOI:10.1080/07357907.2024.2309792 (Source: Cancer Investigation)
Source: Cancer Investigation - February 2, 2024 Category: Cancer & Oncology Authors: Gary H Lyman Christopher H Lyman Nicole M Kuderer Source Type: research
Comorbidity in Small Cell Lung Cancer: Prognostic Impacts of Hypertension/Coronary Artery Disease, Diabetes Mellitus, and Chronic Obstructive Pulmonary Disease
Cancer Invest. 2024 Feb 1:1-13. doi: 10.1080/07357907.2024.2310574. Online ahead of print.ABSTRACTComorbidity, the most important components of which are hypertension/coronary artery disease (HTN/CAD), diabetes mellitus (DM), and chronic obstructive pulmonary disease (COPD), is frequently encountered in small cell lung cancer (SCLC) patients. We aimed to assess the possible impacts of these major comorbidities on the prognoses of SCLC patients. A total of 378 SCLC patients were analyzed retrospectively. We did not ascertain the effect of comorbidity on survival in SCLC patients in general; and similarly, the presence of HT...
Source: Cancer Investigation - February 1, 2024 Category: Cancer & Oncology Authors: Faruk Tas Akin Ozturk Kayhan Erturk Source Type: research
Efficacy of Adjuvant First-Generation TKIs versus Chemotherapy in Patients with Completely Resected EGFR-Mutant Non-Small Cell Lung Cancer: A Meta-Analysis
CONCLUSIONS: In patients with completely resected EGFR-mutant NSCLC, adjuvant first-generation TKIs may delay disease progression but still fail to improve long-term survival compared with conventional chemotherapy.PMID:38224061 | DOI:10.1080/07357907.2024.2303311 (Source: Cancer Investigation)
Source: Cancer Investigation - January 15, 2024 Category: Cancer & Oncology Authors: Bin Shen Dongping Wu Jianjiang Liu Yang Yang Source Type: research
Human Mycobiota and Its Role in Cancer Progression, Diagnostics and Therapeutics: A Link Lesser-Known
Cancer Invest. 2024 Jan 7:1-19. doi: 10.1080/07357907.2024.2301733. Online ahead of print.ABSTRACTAlthough not as well studied as the bacterial component of the human microbiota, the commensal fungi or mycobiota play important roles in maintaining our health by augmenting our immune system. This mycobiota is also associated with various fatal diseases like opportunistic mycoses, and even cancer, with different cancers having respective type-specific mycobiota. The different fungal species which comprise these different intratumoral mycobiota play important roles in cancer progression. The aim of this review paper is to dec...
Source: Cancer Investigation - January 8, 2024 Category: Cancer & Oncology Authors: Souvik Roy Dhrisaj Ray Ishani Laha Lopamudra Choudhury Source Type: research
THE NATURE, ORIGIN, AND EVOLUTION OF LIFE: Part IV Cellular Differentiation and the Emergence of Multicellular Life
Cancer Invest. 2024 Jan 4:1-5. doi: 10.1080/07357907.2024.2302201. Online ahead of print.NO ABSTRACTPMID:38175037 | DOI:10.1080/07357907.2024.2302201 (Source: Cancer Investigation)
Source: Cancer Investigation - January 4, 2024 Category: Cancer & Oncology Authors: Gary H Lyman Christopher H Lyman Nicole M Kuderer Source Type: research
Impact of the multidisciplinary cancer team on the diagnostic and therapeutic care pathway of early breast cancer patients and perception of team members: the experience of a cancer centre in Italy
Cancer Invest. 2023 Dec 27:1-12. doi: 10.1080/07357907.2023.2300442. Online ahead of print.ABSTRACTLiterature on the role of multidisciplinary team (MDT) in cancer is still controversial. We aimed to investigate MDT impact on a panel of indicators in breast cancer care in a single-center retrospective study performed in a Cancer Reference Center in Italy. We analysed the diagnostic and therapeutic care pathway (DTCP) of 266 early breast cancer patients managed by our MDT during 2019-2020.Process indicators reflecting the change of the diagnostic and therapeutic care pathways occurred after the MDT discussion were computed....
Source: Cancer Investigation - December 27, 2023 Category: Cancer & Oncology Authors: Aml Capobianco G Gallucci L Lapadula G Dinardo G La Torre N Sisti L G Sisti Source Type: research
