Assessment of Swallowing Function in Patients with Head and Neck Squamous Cell Carcinoma in High vs. Low Dose Cisplatin
Cancer Invest. 2023 Nov 14:1-13. doi: 10.1080/07357907.2023.2283452. Online ahead of print.ABSTRACTCisplatin-based therapies are standard-of-care for advanced-stage head and neck squamous cell carcinoma (HNSCC). Treatment regimens include 3 weeks of high-dose bolus cisplatin or 6-7 weeks of low-dose weekly cisplatin, both with concurrent radiation. The effects of cisplatin dosage on swallowing function could be further studied. A 237-patient cohort treated for HNSCC at a single center were studied retrospectively. Gastrostomy tube dependence was the primary endpoint. Secondary endpoints included weight changes, esophageal ...
Source: Cancer Investigation - November 14, 2023 Category: Cancer & Oncology Authors: Amber Veldman Annika van Oosbree Madisyn Braun Aarabhi Gurumoorthy William C Spanos Steven Powell Source Type: research
Recurrence patterns and clinical management after a positive sentinel node biopsy in melanoma patients
Conclusions Multimodal strategies are recommended to achieve better results when managing stage III melanoma patients after a positive SNB.PMID:37962565 | DOI:10.1080/07357907.2023.2283459 (Source: Cancer Investigation)
Source: Cancer Investigation - November 14, 2023 Category: Cancer & Oncology Authors: Jacqueline N de Menezes Dante A S M Arra Matheus M L ôbo Clovis A L Pinto Jo ão P S N Lima Milton J B Silva Jo ão P DupratNeto Eduardo Bertolli Source Type: research
Significance of the pretreatment neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in predicting the response to neoadjuvant chemotherapy and survival rates in extremity osteosarcoma: a multicentre prospective study
ConclusionOur study showed that neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios at the baseline can predict the survival of patients with high grade osteosarcoma.PMID:37963292 | DOI:10.1080/07357907.2023.2283456 (Source: Cancer Investigation)
Source: Cancer Investigation - November 14, 2023 Category: Cancer & Oncology Authors: Amir Mohammad Arefpour Maryam Garousi Ahmad Foroughi Saeed Hosseini Mohadeseh Shahin Seyed Alireza Javadinia Source Type: research
THE NATURE, ORIGIN, AND EVOLUTION OF LIFE: Part III The Emergence of Complex Life
Cancer Invest. 2023 Nov 7:1-6. doi: 10.1080/07357907.2023.2281715. Online ahead of print.NO ABSTRACTPMID:37933804 | DOI:10.1080/07357907.2023.2281715 (Source: Cancer Investigation)
Source: Cancer Investigation - November 7, 2023 Category: Cancer & Oncology Authors: Gary H Lyman Christopher H Lyman Nicole M Kuderer Source Type: research
Dose-Dense Docetaxel-Cyclophosphamide and Epirubicin-Cisplatin(ddDCEP): Analysis of an alternative platinum-containing regimen in 116 patients with early triple negative breast cancer
Cancer Invest. 2023 Nov 1:1-18. doi: 10.1080/07357907.2023.2278048. Online ahead of print.ABSTRACTWe assessed the efficacy, tolerability, and cost-effectiveness of a novel neoadjuvant regimen comprising docetaxel-cyclophosphamide alternating with epirubicin-cisplatin (ddDCEP) administered biweekly for 16 weeks in 116 patients with early triple-negative breast cancer. This regimen achieved a high pathological complete response (ypT0/TisN0) rate of 55.2% and favorable survival outcomes (30-month event-free survival, 91.2%; overall survival, 97%). Febrile neutropenia was observed in 4.3% of patients, and 98% completed at leas...
Source: Cancer Investigation - November 1, 2023 Category: Cancer & Oncology Authors: Ashish Singh Josh Thomas Georgy Anjana Joel Divya Bala Thumaty Ajoy Oommen John Nithya Ramnath Tarun K George Parth Sharma Shalom Patole Grace Rebekah Elanthenral Sigamani Marie Therese Manipadam Anish Jacob Cherian Deepak Thomas Abraham Mazhuvanchary Jac Source Type: research
Anxiety, depression and coping strategies during chemotherapy treatment: A comparison of older and younger adults with advanced cancer in Brazil
Cancer Invest. 2023 Oct 26:1-18. doi: 10.1080/07357907.2023.2274033. Online ahead of print.ABSTRACTWe sought to examine differences in anxiety, depression and coping strategies among younger (<64 years old) and older (≥65 years old) patients. Patients were assessed at baseline (T1), mid-point (T2) and on the last day of treatment (T3) using the Hospital Anxiety and Depression Scale and the Ways of Coping. Linear mixed modeling approach was used. The study included 200 patients (gender: 70% women; diagnosis: 30% breast, 22% hematological, 18% gastrointestinal; disease stage: 60% advanced). Older patients who used an em...
Source: Cancer Investigation - October 26, 2023 Category: Cancer & Oncology Authors: Cristiane Decat Bergerot Errol J Philip Paulo Gustavo Bergerot Marianne Razavi David Lee Karen Lynn Clark Matthew Loscalzo Sumanta Kumar Pal William Dale Source Type: research
