Immune Cell Infiltration Types as Biomarkers for the Recurrence Diagnosis and Prognosis of Bladder Cancer
This study aimed to investigate the role of infiltrating immune cell types in diagnosing and predicting bladder cancer recurrence. This study mainly applied some algorithms, including Estimate the Proportion of Immune and Cancer Cells (EPIC), support vector machine-recursive feature elimination (SVM-RFE), random forest out-of-bag (RF-OOB) and least absolute shrinkage and selection operator (LASSO)-Cox regression analysis. We found six immune infiltrating cell types significantly associated with recurrence prognosis and two independent clinical prognostic factors. Infiltrating immune cell types (IICTs) based on the prognost...
Source: Cancer Investigation - February 23, 2024 Category: Cancer & Oncology Authors: Hongwei Xu Dapeng Sun Dahong Zhou Shiheng Sun Source Type: research
NGS-based Tissue-Blood TMB Comparison and Blood-TMB Monitoring in Stage-III Non-Small Cell Lung Cancer Treated with Concurrent Chemoradiotherapy
This study suggests that in patients with LA-NSCLC, b-TMB is a reliable biomarker, and its dynamic monitoring can help distinguish patients who might benefit most from the consolidated immunotherapy.PMID:38390854 | DOI:10.1080/07357907.2024.2316297 (Source: Cancer Investigation)
Source: Cancer Investigation - February 23, 2024 Category: Cancer & Oncology Authors: Luxi Ye Xiao Chu Jianjiao Ni Li Chu Xi Yang Zhengfei Zhu Source Type: research
Immune Cell Infiltration Types as Biomarkers for the Recurrence Diagnosis and Prognosis of Bladder Cancer
This study aimed to investigate the role of infiltrating immune cell types in diagnosing and predicting bladder cancer recurrence. This study mainly applied some algorithms, including Estimate the Proportion of Immune and Cancer Cells (EPIC), support vector machine-recursive feature elimination (SVM-RFE), random forest out-of-bag (RF-OOB) and least absolute shrinkage and selection operator (LASSO)-Cox regression analysis. We found six immune infiltrating cell types significantly associated with recurrence prognosis and two independent clinical prognostic factors. Infiltrating immune cell types (IICTs) based on the prognost...
Source: Cancer Investigation - February 23, 2024 Category: Cancer & Oncology Authors: Hongwei Xu Dapeng Sun Dahong Zhou Shiheng Sun Source Type: research
NGS-based Tissue-Blood TMB Comparison and Blood-TMB Monitoring in Stage-III Non-Small Cell Lung Cancer Treated with Concurrent Chemoradiotherapy
This study suggests that in patients with LA-NSCLC, b-TMB is a reliable biomarker, and its dynamic monitoring can help distinguish patients who might benefit most from the consolidated immunotherapy.PMID:38390854 | DOI:10.1080/07357907.2024.2316297 (Source: Cancer Investigation)
Source: Cancer Investigation - February 23, 2024 Category: Cancer & Oncology Authors: Luxi Ye Xiao Chu Jianjiao Ni Li Chu Xi Yang Zhengfei Zhu Source Type: research
Immune Cell Infiltration Types as Biomarkers for the Recurrence Diagnosis and Prognosis of Bladder Cancer
This study aimed to investigate the role of infiltrating immune cell types in diagnosing and predicting bladder cancer recurrence. This study mainly applied some algorithms, including Estimate the Proportion of Immune and Cancer Cells (EPIC), support vector machine-recursive feature elimination (SVM-RFE), random forest out-of-bag (RF-OOB) and least absolute shrinkage and selection operator (LASSO)-Cox regression analysis. We found six immune infiltrating cell types significantly associated with recurrence prognosis and two independent clinical prognostic factors. Infiltrating immune cell types (IICTs) based on the prognost...
Source: Cancer Investigation - February 23, 2024 Category: Cancer & Oncology Authors: Hongwei Xu Dapeng Sun Dahong Zhou Shiheng Sun Source Type: research
NGS-based Tissue-Blood TMB Comparison and Blood-TMB Monitoring in Stage-III Non-Small Cell Lung Cancer Treated with Concurrent Chemoradiotherapy
This study suggests that in patients with LA-NSCLC, b-TMB is a reliable biomarker, and its dynamic monitoring can help distinguish patients who might benefit most from the consolidated immunotherapy.PMID:38390854 | DOI:10.1080/07357907.2024.2316297 (Source: Cancer Investigation)
Source: Cancer Investigation - February 23, 2024 Category: Cancer & Oncology Authors: Luxi Ye Xiao Chu Jianjiao Ni Li Chu Xi Yang Zhengfei Zhu Source Type: research
Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Concurrent Use of Crocin During Chemoradiation for Esophageal Squamous Cell Carcinoma
Cancer Invest. 2024 Feb 22:1-10. doi: 10.1080/07357907.2024.2319754. Online ahead of print.ABSTRACTCrocin is the major active carotenoid of saffron (Crocus sativus L.). Its pluripotent effects have led to a growing body of literature investigating its antitumor properties as well as its diverse potentials for mood stabilization, normal tissue protection, and inflammation reduction; However, there is a gap in clinical trials testing this substance in cancer patients. In this randomized, double-blind, placebo-controlled clinical trial, patients with newly diagnosed esophageal squamous cell carcinoma were randomly assigned to...
Source: Cancer Investigation - February 22, 2024 Category: Cancer & Oncology Authors: Nima Ebrahimi Seyed Alireza Javadinia Roham Salek Azar Fanipakdel Samaneh Sepahi Mansoureh Dehghani Niloufar Valizadeh Seyed Ahmad Mohajeri Source Type: research
Microvessel Density (MVD) in Patients with Osteosarcoma: A Systematic Review and Meta-Analysis
Cancer Invest. 2024 Jan;42(1):104-114. doi: 10.1080/07357907.2024.2311266. Epub 2024 Feb 12.ABSTRACTA meta-analysis was designed and conducted to estimate the effect of tumoral microvessel density (MVD) on the survival of patients with osteosarcoma. There was no difference between high and low MVD regarding the overall (OS) and disease-free (DFS) survival. Low MVD tumors displayed a lower DFS at the third year of follow-up. Although primary metastases did not affect the mean MVD measurements, tumors with a good chemotherapy response had a higher MVD value. Although no significant differences between tumoral MVD, OS and DFS...
Source: Cancer Investigation - February 12, 2024 Category: Cancer & Oncology Authors: Konstantinos Perivoliotis Panagiotis Ntellas Katerina Dadouli Athina A Samara Sotirios Sotiriou Maria Ioannou Konstantinos Tepetes Source Type: research
Microvessel Density (MVD) in Patients with Osteosarcoma: A Systematic Review and Meta-Analysis
Cancer Invest. 2024 Feb 12:1-11. doi: 10.1080/07357907.2024.2311266. Online ahead of print.ABSTRACTA meta-analysis was designed and conducted to estimate the effect of tumoral microvessel density (MVD) on the survival of patients with osteosarcoma. There was no difference between high and low MVD regarding the overall (OS) and disease-free (DFS) survival. Low MVD tumors displayed a lower DFS at the third year of follow-up. Although primary metastases did not affect the mean MVD measurements, tumors with a good chemotherapy response had a higher MVD value. Although no significant differences between tumoral MVD, OS and DFS ...
Source: Cancer Investigation - February 12, 2024 Category: Cancer & Oncology Authors: Konstantinos Perivoliotis Panagiotis Ntellas Katerina Dadouli Athina A Samara Sotirios Sotiriou Maria Ioannou Konstantinos Tepetes Source Type: research
