Antimicrobial Resistance (AMR)
Br J Biomed Sci. 2023 Jun 28;80:11387. doi: 10.3389/bjbs.2023.11387. eCollection 2023.ABSTRACTAntimicrobial resistance (AMR) has now emerged as a chronic public health problem globally, with the forecast of 10 million deaths per year globally by 2050. AMR occurs when viruses, bacteria, fungi and parasites do not respond to antimicrobial treatments in humans and animals, thus allowing the survival of the microorganism within the host. The prominent cause contributing to the current crisis remains to be the overuse and misuse of antimicrobials, particularly the inappropriate usage of antibiotics, increasing the global burden...
Source: British Journal of Biomedical Science - July 14, 2023 Category: Laboratory Medicine Authors: Ka Wah Kelly Tang Beverley C Millar John E Moore Source Type: research

Innovation, Automation and Informatics Improves Quality in Lerdsin Hospital, Thailand
Br J Biomed Sci. 2023 Jun 19;80:11532. doi: 10.3389/bjbs.2023.11532. eCollection 2023.ABSTRACTThis paper describes a planned, continuous improvement journey, of a laboratory that has installed a system with a single sample touch from blood draw to result. To achieve this, physical connectivity of systems from phlebotomy through pre-analytical to the analytical phase were paired with informatics connectivity from the patient's national identity card to the hospital and laboratory informatics management systems (LIMS) and associated middleware. This allowed accurate time stamps to track turnaround time (TAT). TAT metrics wer...
Source: British Journal of Biomedical Science - July 5, 2023 Category: Laboratory Medicine Authors: Adchada Karnchanaphiboonwong Patcharawadee Sringam Kawinna Niwattakul Teerayut Krommuang Alistair Gammie Source Type: research

Prognostic Role of CD68 < sup > + < /sup > and CD163 < sup > + < /sup > Tumour-Associated Macrophages and PD-L1 Expression in Oral Squamous Cell Carcinoma: A Meta-Analysis
Conclusion: In conclusion, our findings indicate CD163+ can provide prognostic utility in OSCC. However, our data suggests CD68+ TAMs were not associated with any prognostic relevance in OSCC patients, whereas PD-L1 expression may prove to be a differential prognostic marker dependent on tumour location and stage of progression.PMID:37397243 | PMC:PMC10310926 | DOI:10.3389/bjbs.2023.11065 (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - July 3, 2023 Category: Laboratory Medicine Authors: Mohammed Haseeb Chohan Matthew Perry Paul Laurance-Young Vehid M Salih Andrew D Foey Source Type: research