Modern Medical Microbiology: The Fundamentals.
Authors: Rogers DJ PMID: 29447597 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 17, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Collins and Lyne's Microbiological Methods.
Authors: Clarke SC PMID: 29447598 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 17, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Transfusion Science Educational CD-ROM.
Authors: Hill B PMID: 29447599 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 17, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Molecular Hematology.
Authors: Blann AD PMID: 29447602 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 17, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Hematopathology: Genomic Mechanisms of Neoplastic Diseases.
Authors: Blann AD PMID: 29447603 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 17, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Microbiology. An Evolving Science.
Authors: Dempsey M PMID: 29447604 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 17, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Clostridium difficile: methods and protocols.
Authors: Hard S PMID: 29447605 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 17, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Medical Genetics.
Authors: Pinel T PMID: 29447606 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 17, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Healthcare Biotechnology. A Practical Guide.
Authors: Theaker J PMID: 29447607 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 17, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Clinical Biochemistry.
Authors: Lloyd G PMID: 29447608 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 17, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Diagnostic and prognostic value of serum nitric oxide, tumor necrosis factor- α, basic fibroblast growth factor and copper as angiogenic markers in premenopausal breast cancer patients: a case-control study.
This study compares the diagnostic and prognostic values of the angiogenic serum factors nitric oxide (NO), tumour necrosis factor-α (TNFα), basic fibroblast growth factor (bFGF) and copper with those of serum CA15-3 as the standard tumour marker in breast cancer patients. Microvessel density was estimated in CD31-immunostained sections from breast cancer patients. Before surgery, NO, TNFα, bFGF, copper and CA 15-3 were measured in serum samples from 30 premenopausal breast cancer patients in comparison with 15 healthy controls. The diagnostic values of the assayed parameters were compared using receiver ...
Source: British Journal of Biomedical Science - February 17, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Molecular and comparative analyses of the fulllength cytolethal distending toxin (cdt) gene operon and its adjacent genetic loci from urease-positive thermophilic Campylobacter (UPTC) organisms.
Authors: Nakanishi S, Tazumi A, Moore JE, Millar BC, Matsuda M Abstract Molecular and comparative analyses of the full-length cytolethal distending toxin (cdt) gene operon and its adjacent genetic loci (2.7-9.4 kilo base pairs in length) are carried out with 12 urease-positive thermophilic Campylobacter (UPTC) isolates using several polymerase chain reaction (PCR) primer pairs. Three putative open reading frames (ORFs) for cdtA, cdtB and cdtC, two putative promoters and a hypothetically intrinsic ρ-independent transcription terminator were identified in all the operons of the 12 UPTC isolates examined. Although...
Source: British Journal of Biomedical Science - February 17, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Book Reviews.
Authors: Gibbs GJ, Pitt SJ PMID: 29447611 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 17, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

High frequency of metronidazole and clarithromycin-resistant Helicobacter pylori in formalin-fixed, paraffin-embedded gastric biopsies.
Authors: Pourakbari B, Mahmoudi S, Parhiz J, Sadeghi RH, Monajemzadeh M, Mamishi S Abstract BACKGROUND: Clarithromycin and metronidazole resistance of Helicobacter pylori is increasing worldwide and has resulted in a loss in the effectiveness of therapeutic regimens. We aimed to evaluate common mutations of resistance genes to clarithromycin (A2143G, A2142G and A2142C) and metronidazole (rdxA and frxA) in H. pylori strains in formalin-fixed, paraffin-embedded gastric biopsies. METHODS: A total of 110 tissue blocks from children suspected of H. pylori infection were included. After DNA extraction, UreC PCR was p...
Source: British Journal of Biomedical Science - February 17, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Book Reviews.
Authors: Foster JR, Cook J, Mernagh D PMID: 29436274 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 16, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Interleukin (IL)-1 β, IL-6 and IL-8 in nasal secretions: a common role for innate immunity in viral bronchial infection in infants?
Interleukin (IL)-1β, IL-6 and IL-8 in nasal secretions: a common role for innate immunity in viral bronchial infection in infants? Br J Biomed Sci. 2006 Jan;63(4):173-175 Authors: Bermejo-Martin JF, Bernardo D, Dominguez-Gil M, Alonso A, Garcia-Arevalo MC, Pino M, De Lejarazu O, Eiros JM, Ardura J, León AJ, Garrote JA, Resino S, Blanco-Quirós A, Muñoz-Fernández A, Arranz E PMID: 29436295 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 16, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

A new softening agent for use on formalinfixed, paraffin wax-embedded tissue.
Authors: Difford J, Orchard GE PMID: 29436296 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 16, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Biomedical Science in Brief.
Authors: Roberts EL, Davies RA PMID: 29436297 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 16, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Structure and immunological function of oxidised albumin in lung cancer: its potential role as a biomarker of elevated oxidative stress.
Authors: Rasheed Z, Ahmad R, Ali R PMID: 29436298 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 16, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Meningococcal vaccination of crew members is warranted.
Authors: Bröker M, Rao D PMID: 29436299 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 16, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Peroxidase activity and nuclear density analysis (PANDA) in the diagnosis of haematological malignancy.
Authors: Gibbs GJ PMID: 29429395 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 14, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Book Reviews.
Authors: Overfield J, Webb SJ, Wilkinson M, Edirisinghe S PMID: 29429398 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 14, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Book Reviews.
Authors: Dawson M, Hardy S, Blann AD PMID: 29429399 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 14, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Book Reviews.
Authors: Clarke SC, Foster JR, Cook DJ, Knight R, Overfield JA, McLellan DS, Moore GW, Munro RI, Overfield JA, Pitt SJ, Hardy SP PMID: 29429404 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 14, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Book Reviews.
Authors: Whiteside C, Kay I PMID: 29429405 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 14, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Sperm toxicity testing: UK best practice guideline from the Association of Biomedical Andrologists.
Authors: Long S, Woodward B, Tomlinson M Abstract In order to ensure the quality and integrity of diagnostic semen analysis results, materials used should be tested to ensure that they do not interfere with sperm function. As a toxicity test, complex sperm function testing may be considered controversial, since the fertilizing capacity of single sperm can never be assured. In preference, sperm motility offers a unique means of assessing the toxicity of reagents and materials before they are used in routine practice. Motility is the semen parameter most likely to be influenced by the external environment. Indeed, it...
Source: British Journal of Biomedical Science - February 11, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Serum S100 calcium binding protein A4 (S100A4, metatasin) as a diagnostic and prognostic biomarker in epithelial ovarian cancer.
Authors: Lv Y, Niu Z, Guo X, Yuan F, Liu Y PMID: 29421955 [PubMed - as supplied by publisher] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 11, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Extraction of genomic DNA from Pseudomonas aeruginosa: a comparison of three methods.
Authors: Clarke L, Cherie Millar B, Moore JE PMID: 29424283 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 11, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Sequence analysis of partial regions of the 5.8S rRNA internal transcribed region 2 and 28S rRNA of Isospora belli.
Authors: Cherie Millar B, Lowery CJ, Xu J, Dooley JSG, Moore JE PMID: 29424286 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 11, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Lectins as targeting agents - the in vitro binding of lectins to lesions in the eye and mouth.
Authors: Banchonglikitkul C, Smart JD, Gibbs RV, Cook DJ PMID: 29424293 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 11, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Lipoprotein (a) in an immigrant Indian population sample in Australia.
Authors: Devanapalli B, Lee S, Mahajan D, Bermingham M PMID: 29424294 [PubMed] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - February 11, 2018 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Assessment of the comparability of CLSI, EUCAST and Stokes antimicrobial susceptibility profiles for Escherichia coli uropathogenic isolates.
CONCLUSIONS: Our data indicate that the discrepancies generated through using different AST methods and different interpretive guidelines may result in confusion and inaccuracy when prescribing treatment for urinary tract infection. PMID: 29210602 [PubMed - as supplied by publisher] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - December 8, 2017 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Serum sMICA as biomarker in detection of non-small-cell lung carcinoma.
Authors: Xing S, Zhu Y, Sun Y PMID: 29182468 [PubMed - as supplied by publisher] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - November 29, 2017 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Evaluation of antioxidant status of female diabetic patientsin Nnamdi Azikiwe University Teaching Hospital, Anambra State, Nigeria.
This study aims to evaluate the level of antioxidant status in type2 diabetes mellitus (DM) female participants visiting the out-patient diabetic clinic of Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, Anambra State, Nigeria. A total of 86 participants aged 51±10 years were recruited for this study. The test group consists of 43 already confirmed type 2 diabetes mellitus females, while the control group consists of43 apparently healthy females. The test subjects were further subgrouped into good and poor glycaemic control groups, using a cut-off of
Source: British Journal of Biomedical Science - November 3, 2017 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

British Journal of Biomedical Science in 2017: What have we learned?
Authors: Blann A Abstract In 2017 the British Journal of Biomedical Science published 35 articles in the various disciplines that comprise biomedical science. These were 6 reviews, 22 original articles, 6 'In Brief' short reports and one guideline. Of these, the majority were in clinical chemistry (one review, six data papers), microbiology (one review, four data papers), cellular pathology (four data papers) and virology (one review, two data papers). There were two data papers in transfusion science, whilst haematology, cytopathology and immunology were each represented by one review and one data paper. Reflectin...
Source: British Journal of Biomedical Science - October 20, 2017 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

The relationship between red cell distribution width and the risk of Henoch-Sch önlein purpura nephritis.
The relationship between red cell distribution width and the risk of Henoch-Schönlein purpura nephritis. Br J Biomed Sci. 2017 Oct 09;:1-6 Authors: Zhu X, Zhang M, Lan F, Wei H, He Q, Li S, Qin X Abstract INTRODUCTION: Red blood cell distribution width (RDW) is elevated in various inflammatory diseases, but its clinical significance in Henoch-Schönlein purpura nephritis (HSPN) in unknown. The aim of this study was to determine the value of RDW as a risk factor or marker for HSPN in children. METHODS: This was a case-control study of 105 Henoch-Schönlein purpura (HSP) patients, 120 HS...
Source: British Journal of Biomedical Science - October 12, 2017 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Fibro-Mark: a panel of laboratory parameters for predicting significant fibrosis in chronic hepatitis C patients.
Authors: Attallah AM, Omran D, Omran MM, Albannan MS, Zayed RA, Saif S, Farid A, Hassany M, Yosry A Abstract BACKGROUND: Fibrosis markers are useful for the prediction of cirrhosis but clinical scores such as King's score, AST-Platelet ratio index (APRI), Biotechnology research center (BRC), Fibrosis routine test (FRT), Fibro-α score and Fibro-quotient (FibroQ) have limited accuracy for diagnosing significant fibrosis. We hypothesised that new markers (reflecting the balance between hepatic fibrogenesis and fibrolysis) together with other indirect fibrosis markers would together construct a more sensitive and...
Source: British Journal of Biomedical Science - September 27, 2017 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Antibacterial and antifungal activity of chitosan coated iron oxide nanoparticles.
Authors: Nehra P, Chauhan RP, Garg N, Verma K Abstract BACKGROUND AND AIM: The emergence of resistance against antimicrobial agents has led to the development of more efficient agents and new techniques for treatment of various microbial infections. The aim of the present study is to determine the antibacterial and antifungal activity of bare and chitosan coated Fe3O4 nanoparticles (NPs) against five organisms, Escherichia coli (E. coli), Bacillus subtilis (B. subtilis), Candida albicans (C. albicans), Aspergillus niger (A. niger) and Fusarium solani (F. solani). METHODS: Fe3O4 NPs were synthesised by coprecipi...
Source: British Journal of Biomedical Science - September 27, 2017 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

p53 and miR-34b/c genetic variation and their impact on ulcerative colitis susceptibility.
Authors: Hosseinpour Z, Salehi Z, Talesh Sasani S, Aminian K PMID: 28934017 [PubMed - as supplied by publisher] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - September 23, 2017 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

miR-146b measurement in FNA to distinguish papillary thyroid cancer from benign thyroid masses.
Authors: Yang F, Zhang H, Leng X, Hao F, Wang L PMID: 28937915 [PubMed - as supplied by publisher] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - September 23, 2017 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Elevated levels of serum MiR-152 and miR-24 in uterine sarcoma: potential for inducing autophagy via SIRT1 and deacetylated LC3.
Authors: Tong X, Wang X, Wang C, Li L Abstract BACKGROUND: MiRNAs may be associated with the risk of uterine sarcoma and related molecular mechanism remains unclear. METHODS: A total of 101 patients with uterine sarcoma (cases) and 54 healthy subjects (controls) were enrolled. The levels of serum miR-152, miR-205, miR-222, miR-24, miR-150 and sirtuin 1 (SIRT1, an NAD +-dependent class III histone deacetylase) were measured by qRT-PCR. HeLa cells were transfected with the mimics of miR-152 and miR-24. The autophagic rates, and the levels of SIRT1 and acetylation of microtubule-associated protein 1A/1B-light...
Source: British Journal of Biomedical Science - September 22, 2017 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Erratum.
Authors: PMID: 28853986 [PubMed - as supplied by publisher] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - August 31, 2017 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Erratum.
Authors: PMID: 28812430 [PubMed - as supplied by publisher] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - August 18, 2017 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

New embedding and staining systems PrestoCHILL and Presto stainer for application in the advancement of Mohs micrographic surgery.
Authors: Orchard GE, Shams M, d'Amico C, Wojcik K, Ismail F, Mohammad M, Salih R, Shams F, Mallipeddi R Abstract BACKGROUND: Mohs micrographic surgery (MMS) involves evaluation of frozen tissue sections to determine complete circumferential and deep tissue margin clearance of skin tumours. PrestoCHILL and Presto stainer devices are two new innovative tools which bring benefits of automation, speed and efficiency to the preparation of frozen section analysis in MMS. The devices were assessed at Viapath's Tissue Science Mohs laboratory at Guy's Cancer Centre. MATERIAL AND METHODS: A total of 279 samples from 10 a...
Source: British Journal of Biomedical Science - August 10, 2017 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Serum miR-210 and miR-155 expression levels as novel biomarkers for rheumatoid arthritis diagnosis.
Authors: Abdul-Maksoud RS, Sediq AM, Kattaia A, Elsayed W, Ezzeldin N, Abdel Galil SM, Ibrahem RA Abstract BACKGROUND: MicroRNAs play a crucial role in the regulation of immune response. We hypothesised roles for serum miR-210 and miR-155 in the diagnosis of rheumatoid arthritis (RA) and relationships with the clinical and laboratory variables including erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), rheumatoid factor (RF), anti-cyclic citrullinated peptide (CCP) antibodies, tumour necrosis factor-alpha (TNF-α) and interleukin-1β (IL-1β). METHODS: MiR-210 and miR-155 levels were ...
Source: British Journal of Biomedical Science - August 9, 2017 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Serum microRNA-302b: the novel biomarker for diagnosis of acute myocardial infarction.
Authors: Yang S, Fu C, Xu R, Xun Z, Zhao X, Fang R PMID: 28752786 [PubMed - as supplied by publisher] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - July 30, 2017 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Role of miR-29 as marker of risk of acute rejection after heart transplant.
Authors: Guo S, Guo X, Wang S, Nie Q, Ni G, Wang C Abstract BACKGROUND: Circulating miRNAs are potential biomarkers of the pathogenesis of certain diseases and in monitoring therapeutic responses. We hypothesized that serum miR-29 can determine risk of acute cardiac allograft rejection. METHODS: Peripheral vein blood was collected from 50 healthy volunteers and 506 patients during post-transplant surveillance. Serum cardiac troponin I (cTnI) and miR-29 was detected by ELISA and qRT-PCR assay respectively. Rejection risk was defined as International Society of Heart and Lung Transplant score from leukocyte infil...
Source: British Journal of Biomedical Science - July 28, 2017 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

Relative resistance index (RRI) - a scoring system for antibiotic resistance in Pseudomonas aeruginosa.
Authors: Ewing J, McCaughan J, Moore J, Fairley D, Sutherland B, Reid A, Downey D Abstract BACKGROUND: There is a need to measure antibiotic resistance of Pseudomonas aeruginosa (PA) in cystic fibrosis (CF), either qualitatively or quantitatively, to inform patient management. The aim of this study was to develop a simple method by which resistance can be quantified by calculating a relative resistance index (RRI), and to assess correlation of RRIs with clinical variables. METHODS: In our model, RRIs were calculated based on resistance to aztreonam, ceftazidime, ciprofloxacin, colistin, meropenem, tazocin, temi...
Source: British Journal of Biomedical Science - July 28, 2017 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

A dual-label time-resolved fluorescence immunoassay for the simultaneous determination of cystatin C and β2-microglobulin in urine.
CONCLUSION: The present dual-label TRFIA has high sensitivity, specificity and accuracy in clinical sample analysis. This method can be used for the early diagnosis and follow-up surveillance of the contrast-induced nephropathy. PMID: 28730872 [PubMed - as supplied by publisher] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - July 22, 2017 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

RHD-specific microRNA for regulation of the DEL blood group: integration of computational and experimental approaches.
CONCLUSION: This is the first attempt to determine whether miR-98 is involved in RHD expression using computational and experimental approaches. Further investigations are necessary to fully characterize the miRNA genetics in DEL blood group regulation. PMID: 28730912 [PubMed - as supplied by publisher] (Source: British Journal of Biomedical Science)
Source: British Journal of Biomedical Science - July 22, 2017 Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research