Diagnostic Techniques in Autoimmune Blistering Diseases
Br J Biomed Sci. 2023 Nov 24;80:11809. doi: 10.3389/bjbs.2023.11809. eCollection 2023.ABSTRACTAutoimmune blistering diseases (AIBD) comprise a heterogeneous group of uncommon disorders of the skin and mucous membranes, characterised by antibodies targeting structural proteins within epithelial tissue and the underlying basement membrane. There can be significant overlap in clinical presentation of these diseases and accurate diagnosis relies on the detection and characterisation of relevant autoantibodies. Immunofluorescence provides the gold-standard diagnostic tool for these diseases, identifying both tissue-bound autoan...
Source: British Journal of Biomedical Science - December 11, 2023 Category: Laboratory Medicine Authors: John B Mee Source Type: research