PharmaNews
Breast Care 2021;16:94 –95 (Source: Breast Care)
Source: Breast Care - February 16, 2021 Category: Cancer & Oncology Source Type: research
Safety and Clinical Evaluation of Dual Inhibition with Pertuzumab and Trastuzumab Biosimilar SB3 in HER2-Positive Breast Cancer Patients
Conclusion: In this series of HER2-positive breast cancer patients, the combination of SB3 plus pertuzumab was consistent with the known safety and efficacy profile of trastuzumab and pertuzumab combination.Breast Care (Source: Breast Care)
Source: Breast Care - February 10, 2021 Category: Cancer & Oncology Source Type: research
Is Reduction Mammoplasty Cost-Effective? A Cost-Utility Analysis of Surgical Treatment for Macromastia in Germany
Conclusions: These results show that reduction mammoplasty is a treatment that not only improves a patient ’s quality of life but also saves money in the longer term in comparison with expensive and ineffective conservative treatment for macromastia.Breast Care (Source: Breast Care)
Source: Breast Care - February 3, 2021 Category: Cancer & Oncology Source Type: research
Resistance Exercise for Breast Cancer Patients? Evidence from the Last Decade
Conclusion: Upon evaluation of randomized controlled trials (RCTs) from the past decade, RT was found to be feasible and safe. Furthermore, there is evidence on the impact of RT on muscle strength, CRF and QoL amongst other factors. Studies implementing mixes of aerobic and strength exercises are rather common, but RCTs of RT-only protocols remain scarce. Different strength training protocols at distinct stages of breast cancer treatment have been conducted, but with the complexity of treatments and the variety of training styles, a large field of study remains.Key Messages: Although the overall data on RT for breast cance...
Source: Breast Care - January 28, 2021 Category: Cancer & Oncology Source Type: research
Expert Discussion: Highlights from the San Antonio Breast Cancer Symposium, San Antonio, December 8 –11, 2020
Breast Care (Source: Breast Care)
Source: Breast Care - January 26, 2021 Category: Cancer & Oncology Source Type: research
Patient Preferences: Results of a German Adaptive Choice-Based Conjoint Analysis (Market Research Study Sponsored by Eli Lilly and Company) in Patients on Palliative Treatment for Advanced Breast Cancer
Conclusion: Using ACBC analysis, it appears that QoL, OS, and PFS are most important to postmenopausal patients with aBC in relation to cancer treatment. Side effects seem to be less important if OS or PFS are prolonged and the QoL is maintained. Thus, QoL, OS, and PFS should be considered equally when making treatment decisions in aBC.Breast Care (Source: Breast Care)
Source: Breast Care - January 25, 2021 Category: Cancer & Oncology Source Type: research
Low-Dose Methotrexate Use in Idiopathic Granulomatous Mastitis: An Alternative Treatment Method
Conclusion: Low-dose MTX and prednisone treatment for IGM patients, who did not respond to steroids alone, should be considered as an alternative treatment method instead of surgical intervention.Breast Care (Source: Breast Care)
Source: Breast Care - January 22, 2021 Category: Cancer & Oncology Source Type: research
Carboplatin-Cyclophosphamide or Paclitaxel without or with Bevacizumab as First-Line Treatment for Metastatic Triple-Negative Breast Cancer (BOOG 2013-01)
Conclusions:CC and CC+B are safe first-line regimens for mTNBC and the side effects are consistent with those known for each individual agent. pVEGFR-2 concentration did not predict a bevacizumab PFS benefit.Breast Care (Source: Breast Care)
Source: Breast Care - January 22, 2021 Category: Cancer & Oncology Source Type: research
Incorporating Genomic and Genetic Testing into the Treatment of Metastatic Luminal Breast Cancer
Background: Treatment of patients with luminal metastatic breast cancer (MBC) has become even more complex over the last few years as molecular profiling has begun to alter disease management. It is well accepted that MBC is not curable but is treatable. Today we are able to prolong progression-free survival and partly overall survival with targeted and more individual treatment strategies adjusted according to the molecular subtype.Summary: Genetic and genomic testing has become therapeutically relevant in luminal MBC and is therefore an integral component within the treatment spectrum. By now, germline testing ofBRCA1 an...
Source: Breast Care - January 20, 2021 Category: Cancer & Oncology Source Type: research
Assessment of MRI-Detected Breast Lesions: A Benign Correlate on Second-Look Ultrasound Can Safely Exclude Malignancy
Discussion: SLUS is a safe diagnostic tool for the management of MRI-detected lesions and can spare patients from undergoing invasive procedures.Breast Care (Source: Breast Care)
Source: Breast Care - January 18, 2021 Category: Cancer & Oncology Source Type: research
Adherence to Newly Implemented Tamoxifen Therapy for Breast Cancer Patients in Rural Western Ethiopia
Conclusions: Endocrine therapy for BC patients seems feasible in rural Western Ethiopia, although non-adherence due to financial hardship and a less developed health care infrastructure remains a major challenge. We postulate that the implementation of breast nurses could reduce patient and health system barriers and improve initiation of and adherence to endocrine treatment.Breast Care (Source: Breast Care)
Source: Breast Care - January 15, 2021 Category: Cancer & Oncology Source Type: research
False Negativity of Targeted Axillary Dissection in Breast Cancer
Conclusion: Although still in its early days, the FNR of TAD can be low, at least in patients with relatively little axillary involvement and when the marked node is the SLN. All reported methods of lymph node marking seem reliable.Breast Care (Source: Breast Care)
Source: Breast Care - January 11, 2021 Category: Cancer & Oncology Source Type: research
Prevalence, Clinical Significance and Risk Factors for Developing Scar Pain and Sensibility Disorders in Breast Cancer Patients after Breast-Conserving Therapy and Mastectomy
Conclusion: This study demonstrated a high satisfaction with scarring after breast surgery and a low level of scar pain. A lack of postoperative information, as well as a low level of actually performed scar care after surgery were observed. Increased focus should be on improved information on postoperative scare care.Breast Care (Source: Breast Care)
Source: Breast Care - December 30, 2020 Category: Cancer & Oncology Source Type: research
Nipple-Sparing Mastectomy and Breast Reconstruction: Does Incision Matter?
Breast Care (Source: Breast Care)
Source: Breast Care - December 30, 2020 Category: Cancer & Oncology Source Type: research
Erratum
Breast Care (Source: Breast Care)
Source: Breast Care - December 28, 2020 Category: Cancer & Oncology Source Type: research
