Which Patients Need Chemotherapy? From Pathological Risk Factors to Gene Signatures and Evaluation of Endocrine Response
Background: Chemotherapy, used either before or after surgery, has significantly improved survival in early breast cancer. Accurate risk assessment is essential to avoid both overtreatment and undertreatment. This review provides an overview of the evolution of chemotherapy as well as risk factors for tailored systemic therapies in early breast cancer - from pathologic risk factors to gene expression signatures to endocrine response assessment.
Summary: Chemotherapy has improved dramatically in recent decades from its beginnings with conventionally dosed cyclophsphamide plus methotexate plus 5-fluorouracil to dose-dense a...
Source: Breast Care - April 25, 2023 Category: Cancer & Oncology Source Type: research
A second ductoscopy procedure in patients with recurrent and persistent pathological nipple discharge
Conclusion: A second ductoscopy procedure can be considered in the diagnostic work-up of patients suffering from persistent or recurrent PND after an unsuccessful first ductoscopic attempt to avoid unnecessary surgery in about 59% of the cases. (Source: Breast Care)
Source: Breast Care - April 25, 2023 Category: Cancer & Oncology Source Type: research
Tamoxifen treatment for Pubertal Gynecomastia: When to start and how long to continue
Conclusion: Tamoxifen treatment in pubertal gynecomastia was found to be effective and safe. One of the current indications for tamoxifen treatment is having a disc size ≥4 cm and the recommended treatment duration is 4-6 months. However, this study suggests that treatment should be continued for at least 6 months to achieve t he optimal effect. In addition, we recommend that the disc diameter threshold for starting tamoxifen needs to be ≥ 3 cm. (Source: Breast Care)
Source: Breast Care - April 20, 2023 Category: Cancer & Oncology Source Type: research
PharmaNews
Breast Care 2023;18:155 –156 (Source: Breast Care)
Source: Breast Care - April 11, 2023 Category: Cancer & Oncology Source Type: research
Trastuzumab-Deruxtecan: Neue Ära bei HER2-low mBC
Breast Care 2023;18:153 –154 (Source: Breast Care)
Source: Breast Care - April 11, 2023 Category: Cancer & Oncology Source Type: research
Mammakarzinom: Phesgo im h äuslichen Umfeld
Breast Care 2023;18:150 –152 (Source: Breast Care)
Source: Breast Care - April 11, 2023 Category: Cancer & Oncology Source Type: research
St. Gallen/Vienna 2023: Optimization of Treatment for Patients with Primary Breast Cancer – A Brief Summary of the Consensus Discussion
This report by editors ofBREAST CARE summarizes the results of the 2023 international panel votes with respect to locoregional and systemic treatment as a brief news update but does not intend to replace the official St. Gallen Consensus publication that not just reports but also interprets the panel votes and will follow shortly in a major oncological journal. The next (19th) St. Gallen International Breast Cancer Conference will again take place in Vienna (save the date: March 12 –15, 2025). (Source: Breast Care)
Source: Breast Care - April 7, 2023 Category: Cancer & Oncology Source Type: research
St. Gallen/Vienna 2023: Optimization of Treatment for Patients with Primary Breast Cancer - a Brief Summary of the Consensus Discussion
This report by editors of BREAST CARE summarizes the results of the 2023 international panel votes with respect to locoregional and syste mic treatment as a brief news update, but does not intend to replace the official St.Gallen Consensus publication that not just reports but also interprets the panel votes and will follow shortly in a major oncological journal. The next (19th) St.Gallen International Breast Cancer Conference will ag ain take place in Vienna (Save the date: March 12–15, 2025). (Source: Breast Care)
Source: Breast Care - April 7, 2023 Category: Cancer & Oncology Source Type: research
The Role of Social Media and Breast Cancer: How does it impact patients?
Discussion
It is clear that social media has a role to play in healthcare, whether by providing meaningful social connections, delivery of information or psychological support.
Healthcare professionals perhaps should consider the importance of social media in their practice. (Source: Breast Care)
Source: Breast Care - March 30, 2023 Category: Cancer & Oncology Source Type: research
Menopausal Hormone Therapy and the Breast: A Review of Clinical Studies
This article is based on a selective literature search for relevant studies regarding HRT use and the risk of breast cancer in the general population or BRCA carriers, the risk of breast cancer recurrence, or the risk of breast cancer in situ.Summary: HRT can lead to little or no increase in breast cancer risk. The risk depends on the duration and composition of the HRT and decreases after stopping the treatment. Data assessing the oncological safety of HRT after breast cancer are inconsistent. According to current knowledge, HRT is fundamentally contraindicated after breast cancer but can be individually considered after ...
Source: Breast Care - March 17, 2023 Category: Cancer & Oncology Source Type: research
