Morphometric analysis of medial temporal lobe subregions in Alzheimer's disease using high-resolution MRI
Brain Struct Funct. 2023 Jul 24. doi: 10.1007/s00429-023-02683-2. Online ahead of print.ABSTRACTThe spread pattern of progressive degeneration seen in Alzheimer's disease (AD) to small-scale medial temporal lobe subregions is critical for early diagnosis. In this context, it was aimed to examine the morphometric changes of the hippocampal subfields, amygdala nuclei, entorhinal cortex (ERC), and parahippocampal cortex (PHC) using MRI. MRI data of patients diagnosed with 20 Alzheimer's disease dementia (ADD), 30 amnestic mild cognitive impairment (aMCI), and 30 subjective cognitive impairment (SCI) without demographic differ...
Source: Brain Structure and Function - July 24, 2023 Category: Neuroscience Authors: Emre Hari Elif Kurt Cigdem Ulasoglu-Yildiz Ali Bayram Ba şar Bilgic Tamer Demiralp Hakan Gurvit Source Type: research

Morphometric analysis of medial temporal lobe subregions in Alzheimer's disease using high-resolution MRI
Brain Struct Funct. 2023 Jul 24. doi: 10.1007/s00429-023-02683-2. Online ahead of print.ABSTRACTThe spread pattern of progressive degeneration seen in Alzheimer's disease (AD) to small-scale medial temporal lobe subregions is critical for early diagnosis. In this context, it was aimed to examine the morphometric changes of the hippocampal subfields, amygdala nuclei, entorhinal cortex (ERC), and parahippocampal cortex (PHC) using MRI. MRI data of patients diagnosed with 20 Alzheimer's disease dementia (ADD), 30 amnestic mild cognitive impairment (aMCI), and 30 subjective cognitive impairment (SCI) without demographic differ...
Source: Brain Structure and Function - July 24, 2023 Category: Neuroscience Authors: Emre Hari Elif Kurt Cigdem Ulasoglu-Yildiz Ali Bayram Ba şar Bilgic Tamer Demiralp Hakan Gurvit Source Type: research

Morphometric analysis of medial temporal lobe subregions in Alzheimer's disease using high-resolution MRI
Brain Struct Funct. 2023 Jul 24. doi: 10.1007/s00429-023-02683-2. Online ahead of print.ABSTRACTThe spread pattern of progressive degeneration seen in Alzheimer's disease (AD) to small-scale medial temporal lobe subregions is critical for early diagnosis. In this context, it was aimed to examine the morphometric changes of the hippocampal subfields, amygdala nuclei, entorhinal cortex (ERC), and parahippocampal cortex (PHC) using MRI. MRI data of patients diagnosed with 20 Alzheimer's disease dementia (ADD), 30 amnestic mild cognitive impairment (aMCI), and 30 subjective cognitive impairment (SCI) without demographic differ...
Source: Brain Structure and Function - July 24, 2023 Category: Neuroscience Authors: Emre Hari Elif Kurt Cigdem Ulasoglu-Yildiz Ali Bayram Ba şar Bilgic Tamer Demiralp Hakan Gurvit Source Type: research

Application of fluorescence micro-optical sectioning tomography in the cerebrovasculature and applicable vascular labeling methods
This article begins with the background of fMOST technology including a widespread 3D imaging methods comparison and the basic technical principal illustration, followed by the application of fMOST in cerebrovascular research and relevant vascular labeling techniques applicable to different scenarios.PMID:37481741 | DOI:10.1007/s00429-023-02684-1 (Source: Brain Structure and Function)
Source: Brain Structure and Function - July 23, 2023 Category: Neuroscience Authors: Yang Wu Zidong Yang Mingyuan Liu Yan Han Source Type: research

Distribution and synaptic organization of substance P-like immunoreactive neurons in the mouse retina
Brain Struct Funct. 2023 Jul 23. doi: 10.1007/s00429-023-02688-x. Online ahead of print.ABSTRACTSubstance P (SP), a neuroprotective peptidergic neurotransmitter, is known to have immunoreactivity (IR) localized to amacrine and/or ganglion cells in a variety of species' retinas, but it has not yet been studied in the mouse retina. Thus, we investigated the distribution and synaptic organization of SP-IR by confocal and electron microscopy immunocytochemistry in the mouse retina. SP-IR was distributed in the inner nuclear layer (INL), inner plexiform layer (IPL), and ganglion cell layer (GCL). Most of the SP-IR somas belonge...
Source: Brain Structure and Function - July 23, 2023 Category: Neuroscience Authors: Fenglan Wang Wenhui Zhong Qingwen Yang Wenna Zhao Xiaoqing Liu Bilin Rao Xin Lin Jun Zhang Source Type: research

The role of middle frontal gyrus in working memory retrieval by the effect of target detection tasks: a simultaneous EEG-fMRI study
In conclusion, our work deepens the understanding of the neural mechanisms by which visual target detection affects WM retrieval.PMID:37477712 | DOI:10.1007/s00429-023-02687-y (Source: Brain Structure and Function)
Source: Brain Structure and Function - July 21, 2023 Category: Neuroscience Authors: Ping Xu Min Wang Tingting Zhang Junjun Zhang Zhenlan Jin Ling Li Source Type: research

Neurotransmitter and receptor systems in the subthalamic nucleus
Brain Struct Funct. 2023 Jul 21. doi: 10.1007/s00429-023-02678-z. Online ahead of print.ABSTRACTThe Subthalamic Nucleus (STh) is a lens-shaped subcortical structure located ventrally to the thalamus, that despite being embryologically derived from the diencephalon, is functionally implicated in the basal ganglia circuits. Because of this strict structural and functional relationship with the circuits of the basal ganglia, the STh is a current target for deep brain stimulation, a neurosurgical procedure employed to alleviate symptoms in movement disorders, such as Parkinson's disease and dystonia. However, despite the great...
Source: Brain Structure and Function - July 21, 2023 Category: Neuroscience Authors: Aron Emmi Marta Campagnolo Elena Stocco Miryam Carecchio Veronica Macchi Angelo Antonini Raffaele De Caro Andrea Porzionato Source Type: research

The role of middle frontal gyrus in working memory retrieval by the effect of target detection tasks: a simultaneous EEG-fMRI study
In conclusion, our work deepens the understanding of the neural mechanisms by which visual target detection affects WM retrieval.PMID:37477712 | DOI:10.1007/s00429-023-02687-y (Source: Brain Structure and Function)
Source: Brain Structure and Function - July 21, 2023 Category: Neuroscience Authors: Ping Xu Min Wang Tingting Zhang Junjun Zhang Zhenlan Jin Ling Li Source Type: research

Neurotransmitter and receptor systems in the subthalamic nucleus
Brain Struct Funct. 2023 Jul 21. doi: 10.1007/s00429-023-02678-z. Online ahead of print.ABSTRACTThe Subthalamic Nucleus (STh) is a lens-shaped subcortical structure located ventrally to the thalamus, that despite being embryologically derived from the diencephalon, is functionally implicated in the basal ganglia circuits. Because of this strict structural and functional relationship with the circuits of the basal ganglia, the STh is a current target for deep brain stimulation, a neurosurgical procedure employed to alleviate symptoms in movement disorders, such as Parkinson's disease and dystonia. However, despite the great...
Source: Brain Structure and Function - July 21, 2023 Category: Neuroscience Authors: Aron Emmi Marta Campagnolo Elena Stocco Miryam Carecchio Veronica Macchi Angelo Antonini Raffaele De Caro Andrea Porzionato Source Type: research

The role of middle frontal gyrus in working memory retrieval by the effect of target detection tasks: a simultaneous EEG-fMRI study
In conclusion, our work deepens the understanding of the neural mechanisms by which visual target detection affects WM retrieval.PMID:37477712 | DOI:10.1007/s00429-023-02687-y (Source: Brain Structure and Function)
Source: Brain Structure and Function - July 21, 2023 Category: Neuroscience Authors: Ping Xu Min Wang Tingting Zhang Junjun Zhang Zhenlan Jin Ling Li Source Type: research

Changes in functional brain activity patterns associated with computer programming learning in novices
CONCLUSION: Computer programming learning among novices induces functional neuroplasticity within the right inferior frontal gyrus but not the left inferior gyrus (Broca's area).PMID:37474776 | DOI:10.1007/s00429-023-02674-3 (Source: Brain Structure and Function)
Source: Brain Structure and Function - July 20, 2023 Category: Neuroscience Authors: Kenji Hishikawa Kenji Yoshinaga Hiroki Togo Takeshi Hongo Takashi Hanakawa Source Type: research

White and gray matter correlates of theory of mind in autism: a voxel-based morphometry study
In this study, we investigated white matter volume (WMV) and gray matter volume (GMV) differences between matching autistic and nonautistic samples, and how these structural features relate to age and ToM skills, indexed by the Reading the Mind in the Eyes (RMIE) measure. The results showed widespread GMV and WMV differences between the two groups in regions crucial for social processes. The autistic group did not express the typically observed negative GMV and positive WMV correlations with age at the same level as the nonautistic group, pointing to abnormalities in developmental structural changes. In addition, we found ...
Source: Brain Structure and Function - July 15, 2023 Category: Neuroscience Authors: Firat Soylu Kaitlyn May Rajesh Kana Source Type: research

White and gray matter correlates of theory of mind in autism: a voxel-based morphometry study
In this study, we investigated white matter volume (WMV) and gray matter volume (GMV) differences between matching autistic and nonautistic samples, and how these structural features relate to age and ToM skills, indexed by the Reading the Mind in the Eyes (RMIE) measure. The results showed widespread GMV and WMV differences between the two groups in regions crucial for social processes. The autistic group did not express the typically observed negative GMV and positive WMV correlations with age at the same level as the nonautistic group, pointing to abnormalities in developmental structural changes. In addition, we found ...
Source: Brain Structure and Function - July 15, 2023 Category: Neuroscience Authors: Firat Soylu Kaitlyn May Rajesh Kana Source Type: research

White and gray matter correlates of theory of mind in autism: a voxel-based morphometry study
In this study, we investigated white matter volume (WMV) and gray matter volume (GMV) differences between matching autistic and nonautistic samples, and how these structural features relate to age and ToM skills, indexed by the Reading the Mind in the Eyes (RMIE) measure. The results showed widespread GMV and WMV differences between the two groups in regions crucial for social processes. The autistic group did not express the typically observed negative GMV and positive WMV correlations with age at the same level as the nonautistic group, pointing to abnormalities in developmental structural changes. In addition, we found ...
Source: Brain Structure and Function - July 15, 2023 Category: Neuroscience Authors: Firat Soylu Kaitlyn May Rajesh Kana Source Type: research

White and gray matter correlates of theory of mind in autism: a voxel-based morphometry study
In this study, we investigated white matter volume (WMV) and gray matter volume (GMV) differences between matching autistic and nonautistic samples, and how these structural features relate to age and ToM skills, indexed by the Reading the Mind in the Eyes (RMIE) measure. The results showed widespread GMV and WMV differences between the two groups in regions crucial for social processes. The autistic group did not express the typically observed negative GMV and positive WMV correlations with age at the same level as the nonautistic group, pointing to abnormalities in developmental structural changes. In addition, we found ...
Source: Brain Structure and Function - July 15, 2023 Category: Neuroscience Authors: Firat Soylu Kaitlyn May Rajesh Kana Source Type: research