Neonatal olfactory bulbectomy causes dendritic spine retraction in dorsal hippocampal CA3 neurons in female rats and spatial learning deficits in male rats
The objective of the present study was to evaluate learning and memory capacity and dendritic spine density in dorsal hippocampal CA3 neurons. Seven-day-old male and female Wistar rats were subjected to nOBX by suction, we included an intact group as a control (CON) and a sham-operated group (SHAM), too. Spatial learning and memory were measured at 56 days of age using a Morris water maze. A different cohort of experimental groups was used to measure dendritic spine density by Golgi-Cox impregnation. Male rats with nOBX showed a pronounced spatial learning deficit than female rats. Also, there was a significant decrease in...
Source: Brain Structure and Function - November 9, 2023 Category: Neuroscience Authors: H éctor De La Luz Torres Paola Rojas P érez Adriana Berenice Silva G ómez Source Type: research

Altered functional brain networks in coronary heart disease: independent component analysis and graph theoretical analysis
This study aimed to explore the association of CHD with functional connectivity and topological properties of brain networks. A total of 27 patients with CHD and 44 healthy controls (HCs) participated in this study and underwent a resting-state functional magnetic resonance imaging (rs-fMRI) scan. Intra- and internetwork functional connectivity alterations were explored using independent component analysis in CHD patients. Furthermore, graph theoretical analysis was adopted to assess abnormalities in small-world properties and network efficiency metrics of brain networks. Compared to HCs, CHD patients exhibited increased f...
Source: Brain Structure and Function - November 9, 2023 Category: Neuroscience Authors: Simin Lin Puyeh Wu Shaoyin Duan Qianni Du Shujia Guo Zhishang Chen Naiming Wu Xiaoyan Chen Ting Xie Yi Han Hengyu Zhao Source Type: research

Neonatal olfactory bulbectomy causes dendritic spine retraction in dorsal hippocampal CA3 neurons in female rats and spatial learning deficits in male rats
The objective of the present study was to evaluate learning and memory capacity and dendritic spine density in dorsal hippocampal CA3 neurons. Seven-day-old male and female Wistar rats were subjected to nOBX by suction, we included an intact group as a control (CON) and a sham-operated group (SHAM), too. Spatial learning and memory were measured at 56 days of age using a Morris water maze. A different cohort of experimental groups was used to measure dendritic spine density by Golgi-Cox impregnation. Male rats with nOBX showed a pronounced spatial learning deficit than female rats. Also, there was a significant decrease in...
Source: Brain Structure and Function - November 9, 2023 Category: Neuroscience Authors: H éctor De La Luz Torres Paola Rojas P érez Adriana Berenice Silva G ómez Source Type: research

ProbaStem, a pipeline towards the first high-resolution probabilistic atlas of the whole human brainstem
Brain Struct Funct. 2023 Nov 4. doi: 10.1007/s00429-023-02726-8. Online ahead of print.ABSTRACTThe brainstem plays an essential role in many vital functions, such as autonomic control, consciousness and sleep, motricity, somatic afferent function, and cognition. Its involvement in several neurological diseases and the definition of brainstem targets for deep brain stimulation (DBS) explain the need for brainstem atlases describing its structural organization and connectivity from several modalities, from histology to ultrahigh field ex vivo MRI. Nonetheless, these atlases are often limited to a subpart of the brainstem or ...
Source: Brain Structure and Function - November 4, 2023 Category: Neuroscience Authors: Mohammad Seyyed Mohammadi Alexia Planty-Bonjour Fabrice Poupon Ivy Uszynski Cyril Poupon Christophe Destrieux Fr édéric Andersson Source Type: research

ProbaStem, a pipeline towards the first high-resolution probabilistic atlas of the whole human brainstem
Brain Struct Funct. 2023 Nov 4. doi: 10.1007/s00429-023-02726-8. Online ahead of print.ABSTRACTThe brainstem plays an essential role in many vital functions, such as autonomic control, consciousness and sleep, motricity, somatic afferent function, and cognition. Its involvement in several neurological diseases and the definition of brainstem targets for deep brain stimulation (DBS) explain the need for brainstem atlases describing its structural organization and connectivity from several modalities, from histology to ultrahigh field ex vivo MRI. Nonetheless, these atlases are often limited to a subpart of the brainstem or ...
Source: Brain Structure and Function - November 4, 2023 Category: Neuroscience Authors: Mohammad Seyyed Mohammadi Alexia Planty-Bonjour Fabrice Poupon Ivy Uszynski Cyril Poupon Christophe Destrieux Fr édéric Andersson Source Type: research

ProbaStem, a pipeline towards the first high-resolution probabilistic atlas of the whole human brainstem
Brain Struct Funct. 2023 Nov 4. doi: 10.1007/s00429-023-02726-8. Online ahead of print.ABSTRACTThe brainstem plays an essential role in many vital functions, such as autonomic control, consciousness and sleep, motricity, somatic afferent function, and cognition. Its involvement in several neurological diseases and the definition of brainstem targets for deep brain stimulation (DBS) explain the need for brainstem atlases describing its structural organization and connectivity from several modalities, from histology to ultrahigh field ex vivo MRI. Nonetheless, these atlases are often limited to a subpart of the brainstem or ...
Source: Brain Structure and Function - November 4, 2023 Category: Neuroscience Authors: Mohammad Seyyed Mohammadi Alexia Planty-Bonjour Fabrice Poupon Ivy Uszynski Cyril Poupon Christophe Destrieux Fr édéric Andersson Source Type: research

ProbaStem, a pipeline towards the first high-resolution probabilistic atlas of the whole human brainstem
Brain Struct Funct. 2023 Nov 4. doi: 10.1007/s00429-023-02726-8. Online ahead of print.ABSTRACTThe brainstem plays an essential role in many vital functions, such as autonomic control, consciousness and sleep, motricity, somatic afferent function, and cognition. Its involvement in several neurological diseases and the definition of brainstem targets for deep brain stimulation (DBS) explain the need for brainstem atlases describing its structural organization and connectivity from several modalities, from histology to ultrahigh field ex vivo MRI. Nonetheless, these atlases are often limited to a subpart of the brainstem or ...
Source: Brain Structure and Function - November 4, 2023 Category: Neuroscience Authors: Mohammad Seyyed Mohammadi Alexia Planty-Bonjour Fabrice Poupon Ivy Uszynski Cyril Poupon Christophe Destrieux Fr édéric Andersson Source Type: research

Anatomical analyses of collateral prefrontal cortex projections to the basolateral amygdala and the nucleus accumbens core in rats
In conclusion, our data suggested that prefrontal control over the BLA and the NAcc is not entirely independent. The functional importance of the collateral projections awaits further examination.PMID:37910300 | DOI:10.1007/s00429-023-02722-y (Source: Brain Structure and Function)
Source: Brain Structure and Function - November 1, 2023 Category: Neuroscience Authors: Cheng-Wei Shih Chun-Hui Chang Source Type: research

Anatomical analyses of collateral prefrontal cortex projections to the basolateral amygdala and the nucleus accumbens core in rats
In conclusion, our data suggested that prefrontal control over the BLA and the NAcc is not entirely independent. The functional importance of the collateral projections awaits further examination.PMID:37910300 | DOI:10.1007/s00429-023-02722-y (Source: Brain Structure and Function)
Source: Brain Structure and Function - November 1, 2023 Category: Neuroscience Authors: Cheng-Wei Shih Chun-Hui Chang Source Type: research

A map of white matter tracts in a lesser ape, the lar gibbon
Brain Struct Funct. 2023 Oct 31. doi: 10.1007/s00429-023-02709-9. Online ahead of print.ABSTRACTThe recent development of methods for constructing directly comparable white matter atlases in primate brains from diffusion MRI allows us to probe specializations unique to humans, great apes, and other primate taxa. Here, we constructed the first white matter atlas of a lesser ape using an ex vivo diffusion-weighted scan of a brain from a young adult (5.5 years) male lar gibbon. We find that white matter architecture of the gibbon temporal lobe suggests specializations that are reminiscent of those previously reported for grea...
Source: Brain Structure and Function - October 31, 2023 Category: Neuroscience Authors: Katherine L Bryant Paul R Manger Mads F Bertelsen Alexandre A Khrapitchev J érôme Sallet R Austin Benn Rogier B Mars Source Type: research

A map of white matter tracts in a lesser ape, the lar gibbon
Brain Struct Funct. 2023 Oct 31. doi: 10.1007/s00429-023-02709-9. Online ahead of print.ABSTRACTThe recent development of methods for constructing directly comparable white matter atlases in primate brains from diffusion MRI allows us to probe specializations unique to humans, great apes, and other primate taxa. Here, we constructed the first white matter atlas of a lesser ape using an ex vivo diffusion-weighted scan of a brain from a young adult (5.5 years) male lar gibbon. We find that white matter architecture of the gibbon temporal lobe suggests specializations that are reminiscent of those previously reported for grea...
Source: Brain Structure and Function - October 31, 2023 Category: Neuroscience Authors: Katherine L Bryant Paul R Manger Mads F Bertelsen Alexandre A Khrapitchev J érôme Sallet R Austin Benn Rogier B Mars Source Type: research

Inter-brain neural mechanism and influencing factors underlying different cooperative behaviors: a hyperscanning study
Brain Struct Funct. 2023 Oct 30. doi: 10.1007/s00429-023-02700-4. Online ahead of print.ABSTRACTCooperative behavior is a vital social interaction which plays a vital role in improving human survival and reproduction. However, few empirical studies have examined the differences between cooperative behaviors and the underlying neural substrates. In the present study, the brain activity of familiar dyads of the same sex was measured using functional near-infrared spectroscopy during three cooperative tasks (cooperative button-press, tangram, and Jenga tasks). We also measured the dyads' empathic abilities and personality tra...
Source: Brain Structure and Function - October 30, 2023 Category: Neuroscience Authors: Qingming Liu Huimin Cui Bincan Huang Yingying Huang Huimeng Sun Xinyi Ru Mingming Zhang Wei Chen Source Type: research

Inter-brain neural mechanism and influencing factors underlying different cooperative behaviors: a hyperscanning study
Brain Struct Funct. 2023 Oct 30. doi: 10.1007/s00429-023-02700-4. Online ahead of print.ABSTRACTCooperative behavior is a vital social interaction which plays a vital role in improving human survival and reproduction. However, few empirical studies have examined the differences between cooperative behaviors and the underlying neural substrates. In the present study, the brain activity of familiar dyads of the same sex was measured using functional near-infrared spectroscopy during three cooperative tasks (cooperative button-press, tangram, and Jenga tasks). We also measured the dyads' empathic abilities and personality tra...
Source: Brain Structure and Function - October 30, 2023 Category: Neuroscience Authors: Qingming Liu Huimin Cui Bincan Huang Yingying Huang Huimeng Sun Xinyi Ru Mingming Zhang Wei Chen Source Type: research

Evolutionary scaling and cognitive correlates of primate frontal cortex microstructure
Brain Struct Funct. 2023 Oct 27. doi: 10.1007/s00429-023-02719-7. Online ahead of print.ABSTRACTInvestigating evolutionary changes in frontal cortex microstructure is crucial to understanding how modifications of neuron and axon distributions contribute to phylogenetic variation in cognition. In the present study, we characterized microstructural components of dorsolateral prefrontal cortex, orbitofrontal cortex, and primary motor cortex from 14 primate species using measurements of neuropil fraction and immunohistochemical markers for fast-spiking inhibitory interneurons, large pyramidal projection neuron subtypes, seroto...
Source: Brain Structure and Function - October 27, 2023 Category: Neuroscience Authors: Cheryl D Stimpson Jeroen B Smaers Mary Ann Raghanti Kimberley A Phillips Bob Jacobs William D Hopkins Patrick R Hof Chet C Sherwood Source Type: research

Evolutionary scaling and cognitive correlates of primate frontal cortex microstructure
Brain Struct Funct. 2023 Oct 27. doi: 10.1007/s00429-023-02719-7. Online ahead of print.ABSTRACTInvestigating evolutionary changes in frontal cortex microstructure is crucial to understanding how modifications of neuron and axon distributions contribute to phylogenetic variation in cognition. In the present study, we characterized microstructural components of dorsolateral prefrontal cortex, orbitofrontal cortex, and primary motor cortex from 14 primate species using measurements of neuropil fraction and immunohistochemical markers for fast-spiking inhibitory interneurons, large pyramidal projection neuron subtypes, seroto...
Source: Brain Structure and Function - October 27, 2023 Category: Neuroscience Authors: Cheryl D Stimpson Jeroen B Smaers Mary Ann Raghanti Kimberley A Phillips Bob Jacobs William D Hopkins Patrick R Hof Chet C Sherwood Source Type: research